Polycombing the Genome: PcG, trxG, and Chromatin Silencing

Spreading of transcriptional represser SIR3 from telomeric heterochromatin

1996 • 523 citations

Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.

1996 • 460 citations

Genetic modification of heterochromatic association and nuclear organization in Drosophila

1996 • 306 citations

Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression.

1996 • 270 citations

Cosuppression in Drosophila: Gene Silencing of Alcohol dehydrogenase by white-Adh Transgenes Is Polycomb Dependent

1997 • 245 citations

Co-localization of Polycomb protein and GAGA factor on regulatory elements responsible for the maintenance of homeotic gene expression

1997 • 235 citations

PcG complexes and chromatin silencing

1997 • 218 citations

Chromatin Insulator Elements Block the Silencing of a Target Gene by the Drosophila Polycomb Response Element (PRE) but Allow trans Interactions Between PREs on Different Chromosomes

1997 • 205 citations

Drosophila Polycomb-group regulated chromatin inhibits the accessibility of a trans-activator to its target DNA.

1995 • 187 citations

Marking of active genes on mitotic chromosomes

1997 • 170 citations

Murine Polycomb- and trithorax-group genes regulate homeotic pathways and beyond.

1997 • 163 citations

Conversion of Dorsal from an activator to a repressor by the global corepressor Groucho

1997 • 157 citations

Transcriptional silencing by the Polycomb protein in Drosophila embryos.

1995 • 143 citations

Murine Polycomb- and trithorax-group genes regulate homeotic pathways and beyond

1997 • 140 citations

Deconstructing the nucleus: global architecture from local interactions

1997 • 109 citations

A silencer is required for maintenance of transcriptional repression throughoutDrosophiladevelopment

1997 • 106 citations

Probes of chromatin accessibility in the Drosophila bithorax complex respond differently to Polycomb-mediated repression.

1996 • 102 citations