Inhibition of Myogenic bHLH and MEF2 Transcription Factors by the bHLH Protein Twist

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

1990 • 2,273 citations

MyoD or Myf-5 is required for the formation of skeletal muscle

1993 • 1,663 citations

Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene

1993 • 1,314 citations

The MyoD family and myogenesis: Redundancy, networks, and thresholds

1993 • 1,062 citations

Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development

1992 • 973 citations

Myogenin gene disruption results in perinatal lethality because of severe muscle defect

1993 • 912 citations

Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

1991 • 874 citations

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

1995 • 817 citations

Early stages of chick somite development

1995 • 781 citations

Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death

1992 • 700 citations

bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out.

1994 • 686 citations

Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

1989 • 662 citations

A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes.

1989 • 605 citations

twist is required in head mesenchyme for cranial neural tube morphogenesis.

1995 • 595 citations

Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis

1994 • 553 citations

twist and snail as positive and negative regulators during Drosophila mesoderm development.

1991 • 550 citations

Early expression of the myogenic regulatory gene, myf-5, in precursor cells of skeletal muscle in the mouse embryo

1991 • 548 citations

Requirement of MADS Domain Transcription Factor D-MEF2 for Muscle Formation in Drosophila

1995 • 502 citations

Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors.

1992 • 491 citations

Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins.

1992 • 480 citations

Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos.

1988 • 471 citations

Drosophila MEF2, a transcription factor that is essential for myogenesis.

1995 • 426 citations

HLH proteins, fly neurogenesis, and vertebrate myogenesis

1993 • 420 citations

Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis

1995 • 386 citations

Regulation of Muscle Differentiation by the MEF2 Family of MADS Box Transcription Factors

1995 • 348 citations

A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crest

1989 • 339 citations

MATERNAL-ZYGOTIC GENE INTERACTIONS DURING FORMATION OF THE DORSOVENTRAL PATTERN IN DROSOPHILA EMBRYOS

1983 • 338 citations

The prospero gene encodes a divergent homeodomain protein that controls neuronal identity in Drosophila.

1991 • 334 citations

Identification of a myocyte nuclear factor that binds to the muscle-specific enhancer of the mouse muscle creatine kinase gene.

1989 • 326 citations

Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen

1993 • 322 citations

Inactivation of the myogenic bHLH gene MRF4 results in up-regulation of myogenin and rib anomalies.

1995 • 308 citations

MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation.

1990 • 294 citations

Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors.

1993 • 267 citations

Myogenin induces the myocyte-specific enhancer binding factor MEF-2 independently of other muscle-specific gene products.

1991 • 264 citations

The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and the Drosophila twist genes

1991 • 259 citations

Dermo-1: A Novel Twist-Related bHLH Protein Expressed in the Developing Dermis

1995 • 253 citations

Cells with persistent twist expression are the embryonic precursors of adult muscles in Drosophila

1991 • 242 citations

The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer.

1988 • 236 citations

D-MEF2: a MADS box transcription factor expressed in differentiating mesoderm and muscle cell lineages during Drosophila embryogenesis.

1994 • 225 citations

Activation of the Myogenic Lineage by MEF2A, a Factor that Induces and Cooperates with MyoD

1994 • 223 citations

Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome

1995 • 220 citations

Sequential activation of three myogenic regulatory genes during somite morphogenesis in quail embryos

1992 • 210 citations

A Series of Mutations in the D-MEF2 Transcription Factor Reveal Multiple Functions in Larval and Adult Myogenesis in Drosophila

1995 • 209 citations

Paraxis: A Basic Helix-Loop-Helix Protein Expressed in Paraxial Mesoderm and Developing Somites

1995 • 203 citations

Expression of M‐twist during postimplantation development of the mouse

1995 • 173 citations

Inactivation of Myf-6 and Myf-5 genes in mice leads to alterations in skeletal muscle development.

1995 • 172 citations

D-mef2: a Drosophila mesoderm-specific MADS box-containing gene with a biphasic expression profile during embryogenesis.

1994 • 171 citations

M-twist Is an Inhibitor of Muscle Differentiation

1994 • 169 citations

A New Myocyte-Specific Enhancer-Binding Factor That Recognizes a Conserved Element Associated with Multiple Muscle-Specific Genes

1989 • 154 citations

Myogenin and MEF2 Function Synergistically To Activate the MRF4 Promoter during Myogenesis

1995 • 151 citations

Multiple regulatory elements contribute differentially to muscle creatine kinase enhancer activity in skeletal and cardiac muscle.

1993 • 143 citations

Somite subdomains, muscle cell origins, and the four muscle regulatory factor proteins.

1994 • 117 citations

Drosophila MEF2 is regulated by twist and is expressed in both the primordia and differentiated cells of the embryonic somatic, visceral and heart musculature

1995 • 113 citations

The Upstream Muscle-Specific Enhancer of the Rat Muscle Creatine Kinase Gene Is Composed of Multiple Elements

1989 • 109 citations

Brain and muscle creatine kinase genes contain common TA-rich recognition protein-binding regulatory elements.

1990 • 83 citations

Dorso-ventral and rostro-caudal sequential expression of M-twist in the postimplantation murine embryo

1995 • 77 citations

Homeodomain protein MHox and MADS protein myocyte enhancer-binding factor-2 converge on a common element in the muscle creatine kinase enhancer

1994 • 76 citations

The Muscle Creatine Kinase Gene Is Regulated by Multiple Upstream Elements, Including a Muscle-Specific Enhancer

1988 • 74 citations

The role of positive and negative signals in somite patterning

1996 • 67 citations

Myogenin Induces the Myocyte-Specific Enhancer Binding Factor MEF-2 Independently of Other Muscle-Specific Gene Products

1991 • 67 citations

Cloning and characterization of a basic helix-loop-helix protein expressed in early mesoderm and the developing somites.

1994 • 54 citations

The upstream muscle-specific enhancer of the rat muscle creatine kinase gene is composed of multiple elements.

1989 • 43 citations

Activation of Xenopus MyoD Transcription by Members of the MEF2 Protein Family

1994 • 40 citations

Muscle Development: Making Drosophila muscle

1995 • 19 citations