The upstream muscle-specific enhancer of the rat muscle creatine kinase gene is composed of multiple elements.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

1977 • 2,070 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

1986 • 1,150 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster

1986 • 587 citations

Multiple sequence motifs are involved in SV40 enhancer function.

1986 • 511 citations

Fine Structure Genetic Analysis of a β-Globin Promoter

1986 • 479 citations

A lymphocyte-specific enhancer in the mouse immunoglobulin κ gene

1984 • 410 citations

Cooperativity of the glucocorticoid receptor and the CACCC-box binding factor

1988 • 370 citations

Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors

1987 • 356 citations

Diversity of Alpha-Fetoprotein Gene Expression in Mice Is Generated by a Combination of Separate Enhancer Elements

1987 • 315 citations

Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virus.

1987 • 306 citations

The SV40 enhancer can be dissected into multiple segments, each with a different cell type specificity.

1987 • 265 citations

Myogenic lineage determination and differentiation: Evidence for a regulatory gene pathway

1988 • 253 citations

Cellular and molecular biology of muscle development

1990 • 248 citations

A muscle-specific enhancer is located at the 3' end of the myosin light-chain 1/3 gene locus.

1988 • 212 citations

Cell-type specific protein binding to the enhancer of simian virus 40 in nuclear extracts

1986 • 209 citations

Duplicated CArG Box Domains Have Positive and Mutually Dependent Regulatory Roles in Expression of the Human α-Cardiac Actin Gene

1987 • 192 citations

Identification of the major component of the estrogen-induced protein of rat uterus as the BB isozyme of creatine kinase.

1981 • 189 citations

12 Creatine Kinase (Adenosine 5′-Triphosphate-Creatine Phosphotransferase)

1973 • 188 citations

Changes in the mRNA population of chick myoblasts during myogenesis in vitro

1977 • 155 citations

Coordinate accumulation of contractile protein mRNAs during myoblast differentiation

1979 • 153 citations

Expression and regulation of chicken actin genes introduced into mouse myogenic and nonmyogenic cells.

1984 • 114 citations

Two nuclear factors compete for the skeletal muscle actin promoter.

1987 • 102 citations

Identification of a Myocyte Nuclear Factor That Binds to the Muscle-Specific Enhancer of the Mouse Muscle Creatine Kinase Gene

1989 • 101 citations

Cytoplasmic creatine kinase isoenzymes quantitated in tissue specimens obtained at surgery.

1983 • 94 citations

Factors that interact with the rat albumin promoter are present both in hepatocytes and other cell types.

1987 • 86 citations

Identification of Upstream and Intragenic Regulatory Elements That Confer Cell-Type-Restricted and Differentiation-Specific Expression on the Muscle Creatine Kinase Gene

1988 • 86 citations

Distinct tissue specific mitochondrial creatine kinases from chicken brain and striated muscle with a conserved CK framework

1988 • 80 citations

Transcriptional control of the mouse prealbumin (transthyretin) gene: both promoter sequences and a distinct enhancer are cell specific.

1986 • 80 citations

Activation of a preexisting cellular factor as a basis for adenovirus E1A-mediated transcription control.

1988 • 74 citations

The Muscle Creatine Kinase Gene Is Regulated by Multiple Upstream Elements, Including a Muscle-Specific Enhancer

1988 • 74 citations

Nuclear factors binding specific sequences within the immunoglobulin enhancer interact differentially with other enhancer elements.

1986 • 73 citations

Transcriptional Regulation of the Muscle Creatine Kinase Gene and Regulated Expression in Transfected Mouse Myoblasts

1986 • 67 citations

Monovalent antibodies against MM-creatine kinase remove the M line from myofibrils.

1978 • 64 citations

A simple and rapid method for sequencing DNA

1985 • 61 citations

cDNA cloning and mapping of the human creatine kinase M gene to 19q13.

1987 • 61 citations

Subcellular localization of creatine kinase in Torpedo electrocytes: association with acetylcholine receptor-rich membranes.

1985 • 55 citations

Identification of a novel TA-rich DNA binding protein that recognizes a TATA sequence within the brain creatine kinase promoter

1988 • 50 citations

The promoter of the chicken cardiac myosin light chain 2 gene shows cell-specific expression in transfected primary cultures of chicken muscle

1988 • 45 citations

Regulation of Creatine Kinase Induction in Differentiating Mouse Myoblasts

1985 • 44 citations

Binding In Vitro of Multiple Cellular Proteins to Immunoglobulin Heavy-Chain Enhancer DNA

1986 • 43 citations

The Cell-Specific Enhancer of the Mouse Transthyretin (Prealbumin) Gene Binds a Common Factor at One Site and a Liver-Specific Factor(s) at Two Other Sites

1988 • 42 citations

Multiple 5′-Flanking Regions of the Human α-Skeletal Actin Gene Synergistically Modulate Muscle-Specific Expression

1987 • 42 citations

Multiple Positive and Negative 5′ Regulatory Elements Control the Cell-Type-Specific Expression of the Embryonic Skeletal Myosin Heavy-Chain Gene

1987 • 38 citations

Differential Patterns of Transcript Accumulation during Human Myogenesis

1987 • 35 citations

Complex Protein Binding within the Mouse Immunoglobulin Heavy-Chain Enhancer

1987 • 32 citations

Identification of Two Factors Required for Transcription of the Ovalbumin Gene

1986 • 24 citations

DNA-Binding Site for Two Skeletal Actin Promoter Factors Is Important for Expression in Muscle Cells

1988 • 21 citations

Identification of a 43-kDa polypeptide associated with acetylcholine receptor-enriched membranes as MM creatine kinase.

1985 • 19 citations