Ovarian steroids influence cell proliferation in the dentate gyrus of the adult female rat in a dose‐ and time‐dependent manner

Comparative distribution of estrogen receptor-? and -? mRNA in the rat central nervous system

1997 • 2,244 citations

Learning enhances adult neurogenesis in the hippocampal formation

1999 • 2,134 citations

Neurogenesis in the adult is involved in the formation of trace memories

2001 • 2,014 citations

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

1997 • 1,814 citations

Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus

2001 • 1,554 citations

Atlas of estradiol‐concentrating cells in the central nervous system of the female rat

1973 • 1,506 citations

Neurogenesis in the Dentate Gyrus of the Adult Tree Shrew Is Regulated by Psychosocial Stress and NMDA Receptor Activation

1997 • 1,468 citations

Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress

1998 • 1,386 citations

Roles of estradiol and progesterone in regulation of hippocampal dendritic spine density during the estrous cycle in the rat

1993 • 1,066 citations

Estrogen Stimulates a Transient Increase in the Number of New Neurons in the Dentate Gyrus of the Adult Female Rat

1999 • 958 citations

Neurogenesis may relate to some but not all types of hippocampal‐dependent learning

2002 • 854 citations

Immunolocalization of Estrogen Receptor β in the Mouse Brain: Comparison with Estrogen Receptor α

2003 • 818 citations

Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population

1989 • 746 citations

Glial fibrillary acidic protein (GFAP): the major protein of glial intermediate filaments in differentiated astrocytes

1985 • 714 citations

Rapid extension of axons into the CA3 region by adult-generated granule cells

1999 • 597 citations

Serotonin-Induced Increases in Adult Cell Proliferation and Neurogenesis are Mediated Through Different and Common 5-HT Receptor Subtypes in the Dentate Gyrus and the Subventricular Zone

2003 • 506 citations

Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites

2000 • 475 citations

The existence of a typical oestrous cycle in the guinea‐pig—with a study of its histological and physiological changes

1917 • 473 citations

Distribution of estrogen receptor β immunoreactivity in the rat central nervous system

2001 • 469 citations

Neural Gonadal Steroid Actions

1981 • 451 citations

Estradiol Enhances Learning and Memory in a Spatial Memory Task and Effects Levels of Monoaminergic Neurotransmitters

1998 • 441 citations

Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites

2000 • 409 citations

Long-term treatment with estrogen and progesterone enhances acquisition of a spatial memory task by ovariectomized aged rats☆

2000 • 404 citations

Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation: effects on stress hormone levels and adult hippocampal neurogenesis

2002 • 355 citations

A Daily Signal for the LH Surge in the Rat

1975 • 331 citations

Distribution and hormone regulation of estrogen receptor immunoreactive cells in the hippocampus of male and female rats

1997 • 322 citations

17β-Estradiol Reduces Stroke Injury in Estrogen-Deficient Female Animals

1999 • 303 citations

Memory retention is modulated by acute estradiol and progesterone replacement.

2001 • 303 citations

Estradiol facilitates performance as working memory load increases

1999 • 303 citations

Disruption of estrogen receptor β gene impairs spatial learning in female mice

2002 • 249 citations

Estrogen-induced changes in place and response learning in young adult female rats.

2002 • 241 citations

Estrogen is More Than just a “Sex Hormone”: Novel Sites for Estrogen Action in the Hippocampus and Cerebral Cortex

2000 • 238 citations

Estrogen Improves Working But Not Reference Memory and Prevents Amnestic Effects of Scopolamine on a Radial-Arm Maze

1999 • 227 citations

Differential colocalization of estrogen receptor β (ERβ) with oxytocin and vasopressin in the paraventricular and supraoptic nuclei of the female rat brain: An immunocytochemical study

1998 • 220 citations

Estrogen Receptor Messenger RNA Expression in Rat Hypothalamus as a Function of Genetic Sex and Estrogen Dose*

1991 • 211 citations

Autoradiographic localization of estradiol-binding neurons in the rat hippocampal formation and entorhinal cortex

1988 • 205 citations

Estrogen replacement improves spatial reference memory and increases hippocampal synaptophysin in aged female mice

2002 • 204 citations

Coexpression of ERβ with ERα and Progestin Receptor Proteins in the Female Rat Forebrain: Effects of Estradiol Treatment

2001 • 204 citations

Effects of estrogen in the CNS

1999 • 191 citations

Sex differences in cell proliferation, cell death and defensive behavior following acute predator odor stress in adult rats

2003 • 188 citations

Estradiol initially enhances but subsequently suppresses (via adrenal steroids) granule cell proliferation in the dentate gyrus of adult female rats

2003 • 181 citations

Estrogen Improves Performance of Reinforced T-Maze Alternation and Prevents the Amnestic Effects of Scopolamine Administered Systemically or Intrahippocampally

1998 • 180 citations

Evidence for novel estrogen binding sites in the rat hippocampus

2000 • 171 citations

Low levels of estradiol facilitate, whereas high levels of estradiol impair, working memory performance on the radial arm maze.

2002 • 167 citations

Extinction of the Estrogen-Induced Daily Signal for LH Release in the Rat: A Role for the Proestrous Surge of Progesterone

1976 • 153 citations

Low levels of estradiol facilitate, whereas high levels of estradiol impair, working memory performance on the radial arm maze.

2002 • 150 citations

Immunocytochemical localization of nuclear estrogen receptors and progestin receptors within the rat dorsal raphe nucleus

1998 • 148 citations

Ovarian Hormone Replacement to Aged Ovariectomized Female Rats Benefits Acquisition of the Morris Water Maze

2002 • 143 citations

MODIFICATION BY PROGESTERONE OF OESTRADIOL-INDUCED CELL PROLIFERATION, RNA SYNTHESIS AND OESTRADIOL DISTRIBUTION IN THE RAT UTERUS

1972 • 140 citations

Exercise increases blood flow to locomotor, vestibular, cardiorespiratory and visual regions of the brain in miniature swine

2001 • 139 citations

Spatial memory retention is enhanced by acute and continuous estradiol replacement

2004 • 137 citations

Gonadal Steroids, Learning, and Memory

2002 • 130 citations

Acute Stress Persistently Enhances Estrogen Levels in the Female Rat

1999 • 128 citations

Progesterone: Inhibition of rodent sexual behavior

1977 • 126 citations

Seizure-related opening of the blood-brain barrier induced by soman: possible correlation with the acute neuropathology observed in poisoned rats.

1990 • 126 citations

An antagonist of estrogen receptors blocks the induction of adult neurogenesis by insulin‐like growth factor‐I in the dentate gyrus of adult female rat

2003 • 125 citations

Expression of intracellular progesterone receptors in rat brain during different reproductive states, and involvement in maternal behavior

1999 • 118 citations

Hippocampal lesions disrupt maternal, not sexual, behavior in the albino rat.

1967 • 118 citations

Progesterone in Conjunction With Estradiol Has Neuroprotective Effects in an Animal Model of Neurodegeneration

1999 • 116 citations

Effects of Ovariectomy and Estrogen Treatment on Learning and Hippocampal Neurotransmitters in Mice

2002 • 110 citations

The neuronal response to injury as visualized by immunostaining of class III β-tubulin in the rat

1989 • 110 citations

Quantitative analysis of ERα and GAD colocalization in the hippocampus of the adult female rat

2001 • 109 citations

Mitotic cycles in estrogen-treated mice: A radioautographic study

1966 • 107 citations

Estrogen receptor immunoreactivity within subregions of the rat forebrain: neuronal distribution and association with perikarya containing choline acetyltransferase

1999 • 100 citations

Regional, Laminar, and Cellular Distribution of Immunoreactivity for ER and ERss in the Cerebral Cortex of Hormonally Intact, Adult Male and Female Rats

2002 • 99 citations

Effects of oestrogens on cell proliferation and cell cycle kinetics. A hypothesis on the cell cycle effects of antioestrogens

1983 • 96 citations

Distribution of estrogen receptor beta mRNA-containing cells in ovariectomized and estrogen-treated female rat brain

2003 • 91 citations

Estradiol enhances brain glucose uptake in ovariectomized rats

1995 • 90 citations

Neurogenesis in adult canary telencephalon is independent of gonadal hormone levels

1993 • 89 citations

Estradiol Down-Regulation of the Rat Uterine Estrogen Receptor

1991 • 83 citations

Effects of estradiol replacement in ovariectomized rats on conditioned avoidance responses and other behaviors

1991 • 77 citations

Gene expression for estrogen and progesterone receptor mRNAS in rat brain and possible relations to sexually dimorphic functions

1991 • 71 citations

Selective Estrogen Receptor Modulators Regulate Phasic Activation of Hippocampal CA1 Pyramidal Cells by Estrogen

2002 • 66 citations

High levels of estradiol impair spatial performance in the Morris water maze and increase ‘depressive-like’ behaviors in the female meadow vole

2002 • 57 citations

Estrogen-induced cyclin D1 and D3 gene expressions during mouse uterine cell proliferation in vivo: Differential induction mechanism of cyclin D1 and D3

1997 • 57 citations

17 beta-Estradiol overcomes a G1 block induced by HMG-CoA reductase inhibitors and fosters cell cycle progression without inducing ERK-1 and -2 MAP kinases activation.

1996 • 56 citations

Estrogen and Progesterone Receptors in the Endometrium

1997 • 56 citations

Immunocytochemical localization of nuclear estrogen receptors and progestin receptors within the rat dorsal raphe nucleus

1998 • 45 citations

Electrophysiological study of the limbic system in the rat at onset of puberty

1968 • 43 citations

Opposing Effects of Estrogen and Progestins on LDL Oxidation and Vascular Wall Cytotoxicity: Implications for Atherogenesis

1999 • 42 citations

Estrogen treatment alleviates NMDA-antagonist induced hippocampal LTP blockade and cognitive deficits in ovariectomized mice

2002 • 38 citations

Short-Term Effects of Physiological and Pharmacological Doses of Estradiol on Estrogen Receptor and Uterine Growth

1991 • 35 citations

Comparative distribution of estrogen receptor α and β immunoreactivities in the forebrain and the midbrain of the female guinea pig

2004 • 33 citations

Chronic stress exposure influences local cerebral blood flow in the rat hippocampus

1999 • 33 citations

Long-term glucocorticoid treatments decrease local cerebral blood flow in the rat hippocampus, in association with histological damage

1997 • 33 citations

Effects of progesterone derivatives, dihydroprogesterone and tetrahydroprogesterone, on the subependymal layer of the adult rat

2003 • 29 citations

Tissue Differences in Estrogen Receptor Dynamics: Nuclear Retention, Rate of Replenishment, and Transient Receptor Loss Vary in Hypothalamus, Pituitary, and Uterus of C57BL/6J Mice*

1987 • 26 citations

Blood-brain barrier permeability: Regional alterations after acute and chronic administration of ethinyl estradiol

1990 • 22 citations

Dose-dependent effects of 17-ß-estradiol on pituitary thyrotropin content and secretion in vitro

1997 • 21 citations

Differential effects of estradiol and its analogs on cyclin D1 and CDK4 expression in estrogen receptor positive MCF-7 and estrogen receptor-transfected MCF-10AEwt5 cells.

1998 • 18 citations

Differential Effects of Amygdaloid and Hippocampal Lesions on Female Puberty

1974 • 16 citations

Inhibition of Prolactin Secretion Delays Extinction of Circadian LH Surges in Ovariectomized Rats Bearing Estradiol Implants

1983 • 16 citations

Influence of Orchidectomy and Ovariectomy on the Blood-Brain Barrier Permeability During Bicuculline-Induced Seizures

1998 • 12 citations

Proliferative Effects of Estradiol, Progesterone, and Two CB Congeners and Their Metabolites on Gray Seal (Halichoerus grypus) Uterine Myocytes in Vitro

2003 • 8 citations

Inhibitory Effect of Progesterone on Sexual Receptivity in Female Rats: A Temporal Relationship to Estrogen Administration

1996 • 7 citations

A possible mechanism of the puberty-delaying effect of hippocampal lesions in female rats.

1977 • 4 citations

Time course of anterior pituitary estrogen receptor after low 17β-estradiol doses in ovariectomized rats

1985 • 2 citations