Low levels of estradiol facilitate, whereas high levels of estradiol impair, working memory performance on the radial arm maze.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (68)
Comparative distribution of estrogen receptor-? and -? mRNA in the rat central nervous system
1997 • 2,244 citations
Hippocampus, space, and memory
1979 • 2,033 citations
Estrogen Actions in the Central Nervous System1
1999 • 1,381 citations
D1 Dopamine Receptors in Prefrontal Cortex: Involvement in Working Memory
1991 • 1,365 citations
Functional differentiation in the hippocampus
1998 • 1,301 citations
Plasma Concentration of LH, FSH, Prolactin, Progesterone and Estradiol-17β Throughout the 4-Day Estrous Cycle of the Rat
1974 • 1,296 citations
On the role of the hippocampus in learning and memory in the rat
1993 • 1,116 citations
Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons
1990 • 1,080 citations
Roles of estradiol and progesterone in regulation of hippocampal dendritic spine density during the estrous cycle in the rat
1993 • 1,066 citations
A triple dissociation of memory systems: Hippocampus, amygdala, and dorsal striatum.
2013 • 1,059 citations
Differential effects of fornix and caudate nucleus lesions on two radial maze tasks: evidence for multiple memory systems
1989 • 1,000 citations
Estrogen Stimulates a Transient Increase in the Number of New Neurons in the Dentate Gyrus of the Adult Female Rat
1999 • 958 citations
Spatial memory and hippocampal function
1979 • 940 citations
Spatial learning impairment parallels the magnitude of dorsal hippocampal lesions, but is hardly present following ventral lesions
1993 • 877 citations
Regional and cellular fractionation of working memory
1996 • 821 citations
Gender Differences in Dopaminergic Function in Striatum and Nucleus Accumbens
1999 • 689 citations
Variations in the Hypothalamic-Pituitary-Adrenal Response to Stress during the Estrous Cycle in the Rat
1991 • 664 citations
A behavioural analysis of spatial localization following electrolytic, kainate- or colchicine-induced damage to the hippocampal formation in the rat
1983 • 590 citations
Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats
1994 • 487 citations
D1Receptor Modulation of Hippocampal–Prefrontal Cortical Circuits Integrating Spatial Memory with Executive Functions in the Rat
1998 • 482 citations
Estradiol Enhances Learning and Memory in a Spatial Memory Task and Effects Levels of Monoaminergic Neurotransmitters
1998 • 441 citations
The nature of the effect of female gonadal hormone replacement therapy on cognitive function in post-menopausal women: a meta-analysis
2000 • 434 citations
LTP varies across the estrous cycle: enhanced synaptic plasticity in proestrus rats
1995 • 430 citations
Spatial and nonspatial learning across the rat estrous cycle.
1997 • 392 citations
Estrogen-Mediated Structural and Functional Synaptic Plasticity in the Female Rat Hippocampus
1998 • 384 citations
Estrogen Enhances Performance of Female Rats during Acquisition of a Radial Arm Maze
1997 • 355 citations
Estradiol facilitates performance as working memory load increases
1999 • 303 citations
Estrogen effects on cognition in menopausal women
1997 • 292 citations
Dose-dependent effects of the dopamine D1 receptor agonists A77636 or SKF81297 on spatial working memory in aged monkeys.
1997 • 292 citations
Estrus-associated decrements in a water maze task are limited to acquisition
1995 • 282 citations
A Beneficial Effect of Estrogen on Working Memory in Postmenopausal Women Taking Hormone Replacement Therapy
2000 • 247 citations
Estrogen modulates sexually dimorphic contextual fear conditioning and hippocampal long-term potentiation (LTP) in rats11Published on the World Wide Web on 1 December 2000.
2001 • 238 citations
Gonadal Hormone Levels and Spatial Learning Performance in the Morris Water Maze in Male and Female Meadow Voles, Microtus pennsylvanicus
1995 • 235 citations
Effects of Estrogen Replacement on the Relative Levels of Choline Acetyltransferase, trkA, and Nerve Growth Factor Messenger RNAs in the Basal Forebrain and Hippocampal Formation of Adult Rats
1994 • 232 citations
Estrogen Improves Working But Not Reference Memory and Prevents Amnestic Effects of Scopolamine on a Radial-Arm Maze
1999 • 227 citations
Effects of estradiol on radial arm maze performance of young and aged rats
1994 • 220 citations
Spatial learning and memory at defined points of the estrous cycle: Effects on performance of a hippocampal-dependent task.
1997 • 202 citations
Effects of lesions to amygdala, ventral subiculum, medial prefrontal cortex, and nucleus accumbens on the reaction to novelty: Implications for limbic--striatal interactions.
1996 • 197 citations
Acute Administration of Estrogen and Progesterone Impairs the Acquisition of the Spatial Morris Water Maze in Ovariectomized Rats
2000 • 192 citations
Posttraining Estradiol Injections Enhance Memory in Ovariectomized Rats: Cholinergic Blockade and Synergism
1997 • 179 citations
Estrogen Replacement Therapy May Protect against Intellectual Decline in Postmenopausal Women
1995 • 175 citations
Intra-hippocampal estradiol infusion enhances memory in ovariectomized rats
1997 • 173 citations
High levels of estradiol disrupt conditioned place preference learning, stimulus response learning and reference memory but have limited effects on working memory
2001 • 173 citations
Evidence for novel estrogen binding sites in the rat hippocampus
2000 • 171 citations
Estrogen affects performance of ovariectomized rats in a two-choice water-escape working memory task
1996 • 168 citations
Reproductive status influences cell proliferation and cell survival in the dentate gyrus of adult female meadow voles: a possible regulatory role for estradiol
2001 • 161 citations
Effects of Ovarian Hormones and Environment on Radial Maze and Water Maze Performance of Female Rats
1999 • 160 citations
Ventral hippocampal dopamine D1 and D2 systems and spatial working memory in rats
1999 • 160 citations
Local modulation of basal forebrain: effects on working and reference memory
1994 • 151 citations
Cyclical changes in endogenous levels of oestrogen modulate the induction of LTD and LTP in the hippocampal CA1 region
1999 • 149 citations
Spatial Working Memory and Hippocampal Size across Pregnancy in Rats
2000 • 140 citations
Granule Cells in Aging Rats Are Sexually Dimorphic in Their Response to Estradiol
1999 • 135 citations
Stability of Spatial Working Memory across the Estrous Cycle of Long–Evans Rats
1997 • 135 citations
Acute Stress Persistently Enhances Estrogen Levels in the Female Rat
1999 • 128 citations
Testing neural network models of memory with behavioral experiments
2000 • 127 citations
Allocentric spatial and tactile memory impairments in rats with dorsal caudate lesions are affected by preoperative behavioral training.
1989 • 118 citations
Ovariectomy and estradiol treatment affect the dopamine transporter and its gene expression in the rat brain
1997 • 111 citations
Inhibition of striatal dopamine transporter activity by 17β-estradiol
1998 • 107 citations
Effects of chronic estrogen treatment on dopamine concentrations and turnover in discrete brain nuclei of ovariectomized rats
1981 • 100 citations
Modulation of mesolimbic dopaminergic activity over the rat estrous cycle
1997 • 96 citations
The modulation of Pavlovian memory
2000 • 87 citations
Acquisition of a complex place task in rats with selective ibotenate lesions of hippocampal formation: Combined lesions of subiculum and entorhinal cortex versus hippocampus.
1988 • 85 citations
Retention of reference memory following ischemic hippocampal damage
1987 • 83 citations
Estrogen and NMDA receptor antagonism: effects upon reference and working memory
1999 • 72 citations
Attenuation of dopamine uptake in vivo following priming with estradiol benzoate
1999 • 72 citations
Sex-related differences in cortical function after medial frontal lesions in rats.
1996 • 71 citations
Estradiol Enhances the Induction of Homosynaptic Long-Term Depression in the CA1 Region of the Adult, Ovariectomized Rat
2000 • 41 citations
Guidelines for Optimizing Growth Hormone Replacement Therapy in Adults
1997 • 39 citations