Estrogen treatment alleviates NMDA-antagonist induced hippocampal LTP blockade and cognitive deficits in ovariectomized mice

Place navigation impaired in rats with hippocampal lesions

1982 • 6,277 citations

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood

1990 • 1,352 citations

Roles of estradiol and progesterone in regulation of hippocampal dendritic spine density during the estrous cycle in the rat

1993 • 1,066 citations

Estradiol regulates hippocampal dendritic spine density via an N-methyl- D-aspartate receptor-dependent mechanism

1994 • 679 citations

Estradiol Increases the Sensitivity of Hippocampal CA1 Pyramidal Cells to NMDA Receptor-Mediated Synaptic Input: Correlation with Dendritic Spine Density

1997 • 679 citations

The quantitative measurement of motor inco-ordination in naive mice using an accelerating rotarod

1968 • 539 citations

17β-Estradiol Enhances NMDA Receptor-Mediated EPSPs and Long-Term Potentiation

1999 • 505 citations

Long-term and short-term electrophysiological effects of estrogen on the synaptic properties of hippocampal CA1 neurons

1992 • 449 citations

Estradiol Enhances Learning and Memory in a Spatial Memory Task and Effects Levels of Monoaminergic Neurotransmitters

1998 • 441 citations

LTP varies across the estrous cycle: enhanced synaptic plasticity in proestrus rats

1995 • 430 citations

Differential Regulation of NMDAR1 mRNA and Protein by Estradiol in the Rat Hippocampus

1996 • 376 citations

Estrogen Enhances Performance of Female Rats during Acquisition of a Radial Arm Maze

1997 • 355 citations

Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus.

1992 • 284 citations

Estrus-associated decrements in a water maze task are limited to acquisition

1995 • 282 citations

Estrogen facilitates induction of long term potentiation in the hippocampus of awake rats1First published on the World Wide Web on 4 November 1997.1

1997 • 234 citations

Electrical Activity During the Estrous Cycle of the Rat: Cyclic Changes in Limbic Structures

1968 • 227 citations

Genetically modified mice and cognition

1998 • 203 citations

Spatial learning and memory at defined points of the estrous cycle: Effects on performance of a hippocampal-dependent task.

1997 • 202 citations

Estrogen Replacement Enhances Acquisition of a Spatial Memory Task and Reduces Deficits Associated with Hippocampal Muscarinic Receptor Inhibition

1999 • 198 citations

Acute Administration of Estrogen and Progesterone Impairs the Acquisition of the Spatial Morris Water Maze in Ovariectomized Rats

2000 • 192 citations

Estrogen Improves Performance of Reinforced T-Maze Alternation and Prevents the Amnestic Effects of Scopolamine Administered Systemically or Intrahippocampally

1998 • 180 citations

Sexually Dimorphic Spatial Learning in Meadow Voles Microtus Pennsylvanicus and Deer Mice Peromyscus Maniculatus

1996 • 179 citations

Factors regulating the magnitude of long-term potentiation induced by theta pattern stimulation

1992 • 178 citations

Estradiol Increases Spine Density and NMDA-Dependent Ca²⁺Transients in Spines of CA1 Pyramidal Neurons From Hippocampal Slices

1999 • 177 citations

Posttraining Estrogen and Memory Modulation

1998 • 174 citations

Excitatory amino acid antagonists and memory: Effect of drugs acting at N-methyl-d-aspartate receptors in learning and memory tasks

1990 • 169 citations

Estradiol selectively regulates agonist binding sites on the N-methyl-D- aspartate receptor complex in the CA1 region of the hippocampus

1992 • 169 citations

Spatial learning and memory at defined points of the estrous cycle: Effects on performance of a hippocampal-dependent task.

1997 • 168 citations

Effects of Ovarian Hormones and Environment on Radial Maze and Water Maze Performance of Female Rats

1999 • 160 citations

Immediate and long-lasting effects of MK-801 on motor activity, spatial navigation in a swimming pool and EEG in the rat

1989 • 159 citations

Detailed behavioral analysis of water maze acquisition under APV or CNQX: Contribution of sensorimotor disturbances to drug-induced acquisition deficits.

1996 • 150 citations

Cyclical changes in endogenous levels of oestrogen modulate the induction of LTD and LTP in the hippocampal CA1 region

1999 • 149 citations

Detailed behavioral analysis of water maze acquisition under APV or CNQX: Contribution of sensorimotor disturbances to drug-induced acquisition deficits.

1996 • 123 citations

Handbook of Molecular-Genetic Techniques for Brain and Behavior Research

1999 • 118 citations

Sex Differences in the Activational Effect of ERα on Spatial Learning

1998 • 113 citations

Estrogen modulates spontaneous alternation and the cholinergic phenotype in the basal forebrain

1999 • 102 citations

Differential contributions of ovarian and extraovarian factors to age-related reductions in plasma estradiol and progesterone during the estrous cycle of C57BL/6J mice.

1992 • 101 citations

In mice tonic estrogen replacement therapy improves non-spatial and spatial memory in a water maze task

1999 • 78 citations

Testing hypotheses of spatial learning: the role of NMDA receptors and NMDA-mediated long-term potentiation

1997 • 73 citations

Estrogen and NMDA receptor antagonism: effects upon reference and working memory

1999 • 72 citations

Chemically-diverse ligands at the glycine B site coupled to (NMDA) receptors selectively block the late phase of formalin-induced pain in mice

1994 • 62 citations

Effects of competitive and noncompetitive NMDA receptor antagonists on kindling and LTP

1991 • 58 citations

In vivo effects of follicle-stimulating hormone-related synthetic peptides on the mouse estrous cycle.

1996 • 39 citations

Induction and duration of long-term potentiation in the hippocampus of the freely moving mouse

1997 • 39 citations

Differential contributions of ovarian and extraovarian factors to age- related reductions in plasma estradiol and progesterone during the estrous cycle of C57BL/6J mice

1992 • 36 citations

Effects of combined block of α1-adrenoceptors and NMDA receptors on spatial and passive avoidance behavior in rats

1996 • 33 citations

Chronic treatment with oestradiol does not alter in vitro LTP in subfield CA1 of the female rat hippocampus

1999 • 20 citations

In vivo effects of follicle-stimulating hormone-related synthetic peptides on the mouse estrous cycle

1996 • 12 citations