Granulocyte colony‐stimulating factor and drugs elevating extracellular adenosine synergize to enhance haematopoietic reconstitution in irradiated mice

Early Signals in the Mitogenic Response

1986 • 1,498 citations

Differentiation and proliferation of hematopoietic stem cells

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Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

1990 • 945 citations

Adenosine receptors: targets for future drugs

1982 • 681 citations

Hematopoietic regulators: redundancy or subtlety?

1993 • 473 citations

Adenosine and the concept of ‘retaliatory metabolites’

1984 • 422 citations

Nucleoside and nucleobase transport in animal cells

1988 • 367 citations

Adenosine; a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils.

1985 • 345 citations

Granulocyte colony-stimulating factor enhances interleukin 3-dependent proliferation of multipotential hemopoietic progenitors.

1988 • 296 citations

Differential regulatory effects of adenosine on cytokine release by activated human monocytes.

1994 • 287 citations

Myeloid cell kinetics in mice treated with recombinant interleukin-3, granulocyte colony-stimulating factor (CSF), or granulocyte-macrophage CSF in vivo

1991 • 172 citations

The effects on hematopoiesis of recombinant stem cell factor (ligand for c-kit) administered in vivo to mice either alone or in combination with granulocyte colony-stimulating factor

1991 • 169 citations

Induction of neutrophilic granulocytosis in mice by administration of purified human native granulocyte colony-stimulating factor (G-CSF)

1987 • 141 citations

Physiological and pathological roles of purines: An update

1993 • 129 citations

Purine nucleosides and nucleotides stimulate proliferation of a wide range of cell types

1992 • 109 citations

The Hydrolysis of Extracellular Adenine Nucleotides by Arterial Smooth Muscle Cells

1989 • 105 citations

Extracellular purine nucleosides stimulate cell division and morphogenesis: Pathological and physiological implications

1992 • 88 citations

Hemopoietic effects of short-term in vivo treatment of mice with various doses of rhG-CSF.

1990 • 70 citations

Therapeutic administration of recombinant human granulocyte colony‐stimulating factor accelerates hemopoietic regeneration and enhances survival in a murine model of radiation‐induced myelosuppression

1990 • 64 citations

Effects of recombinant granulocyte colony-stimulating factor (rG-CSF) and recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) on acute radiation hematopoietic injury in mice.

1989 • 62 citations

Effects of combined administration of interleukin-6 and granulocyte colony-stimulating factor on recovery from radiation-induced hemopoietic aplasia.

1993 • 57 citations

ADENOSINE INCREASES INTERLEUKIN 6 RELEASE AND DECREASES TUMOUR NECROSIS FACTOR RELEASE FROM RAT ADRENAL ZONA GLOMERULOSA CELLS, OVARIAN CELLS, ANTERIOR PITUITARY CELLS AND PERITONEAL MACROPHAGES

1997 • 56 citations

Synergistic effects of thrombopoietin and granulocyte colony- stimulating factor on neutrophil recovery in myelosuppressed mice

1996 • 53 citations

Adenosine receptors and beyond: molecular mechanisms of physiological regulation.

1990 • 49 citations

Elevation of Extracellular Adenosine Induces Radioprotective Effects in Mice

1993 • 48 citations

The diadenosine polyphosphates Ap3A and Ap4A and adenosine triphosphate interact with granulocyte-macrophage colony-stimulating factor to delay neutrophil apoptosis: implications for neutrophil: platelet interactions during inflammation

1996 • 48 citations

G‐ and GM‐CSF in oncology and oncological haematology

1994 • 48 citations

Kinetic response of human marrow myeloid progenitor cells to in vivo treatment of patients with granulocyte colony-stimulating factor is different from the response to treatment with granulocyte-macrophage colony-stimulating factor.

1994 • 43 citations

The biology of macrophages: II Inflammation and tumors

1994 • 42 citations

Synergistic effect of granulocyte colony-stimulating factor and drugs elevating extracellular adenosine on neutrophil production in mice

1995 • 39 citations

The kinetics of murine hematopoietic stem cells in vivo in response to prolonged increased mature blood cell production induced by granulocyte colony-stimulating factor

1995 • 33 citations

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1980 • 32 citations

Radioprotection of Mouse Hemopoiesis by Dipyridamole and Adenosine Monophosphate in Fractionated Treatment

1995 • 26 citations

Kinetics of rG-CSF-induced neutrophilia in mice.

1992 • 26 citations

Enhancement of monocytopoiesis by granulocyte colony-stimulating factor: evidence for secondary cytokine effects in vivo.

1995 • 25 citations

Concepts of Hemopoietic Cell Amplification. Synergy, Redundancy and Pleiotropy of Cytokines Affecting the Regulation of Erythropoiesis

1996 • 24 citations

Recombinant human granulocyte‐colony stimulating factor and recombinant human macrophage colony stimulating factor synergize in vivo to enhance proliferation of granulocyte‐macrophage, erythroid, and multipotential progenitor cells in mice

1988 • 22 citations

Modulation of erythropoietin production by selective adenosine agonists and antagonists in normal and anemic rats

1996 • 22 citations

Protection of early cellular damage in 1 Gy-irradiated mice by the elevation of extracellular adenosine

1992 • 20 citations

Effect of adenine nucleotides on granulopoiesis and lithium-induced granulocytosis in long-term bone marrow cultures.

1986 • 20 citations

Hematopoietic stem cell cytokine response

1995 • 18 citations

Postirradiation administration of adenosine monophosphate combined with dipyridamole reduces early cellular damage in mice

1993 • 11 citations

Combinations of colony-stimulating factors promote enhanced proliferative potential in enriched granulocyte-macrophage colony-forming cells.

1994 • 9 citations