Purine nucleosides and nucleotides stimulate proliferation of a wide range of cell types

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

1963 • 2,742 citations

Interleukin 1 of the central nervous system is produced by ameboid microglia.

1986 • 858 citations

Long-term culture of capillary endothelial cells.

1979 • 780 citations

Purification of the fibroblast growth factor activity from bovine brain.

1978 • 498 citations

Extracellular Adenosine, Inosine, Hypoxanthine, and Xanthine in Relation to Tissue Nucleotides and Purines in Rat Striatum During Transient Ischemia

1987 • 424 citations

Purine Receptors in Mammalian Tissues: Pharmacology and Functional Significance

1987 • 302 citations

P2-purinergic receptors are coupled to two signal transduction systems leading to inhibition of cAMP generation and to production of inositol trisphosphate in rat hepatocytes.

1987 • 213 citations

Adenosine and hypoxia stimulate proliferation and migration of endothelial cells

1988 • 170 citations

Adenosine and Adenosine Receptors

1990 • 142 citations

Adenosine and its nucleotides stimulate proliferation of chick astrocytes and human astrocytoma cells

1992 • 114 citations

Purinergic stimulation of cell division and differentiation: Mechanisms and pharmacological implications

1992 • 77 citations

Isopentenyladenosine Stimulates and Inhibits Mitosis of Human Lymphocytes Treated with Phytohemagglutinin

1969 • 75 citations

Mechanisms leading to adenosine-stimulated proliferation of microvascular endothelial cells

1990 • 75 citations

Adenosine receptor activation in quiescent Swiss 3T3 cells

1982 • 71 citations

The relationship between purines, pyrimidines, nucleosides, and glutamine for fibroblast cell proliferation

1984 • 64 citations

Cytokinins: Metabolism and Biological Activity of N⁶-(Δ²-Isopentenyl)adenosine and N⁶-(Δ²-Isopentenyl)adenine in Tobacco Cells and Callus

1977 • 62 citations

Purinergic stimulation of astroblast proliferation: Guanosine and its nucleotides stimulate cell division in chick astroblasts

1991 • 58 citations

Subtypes of P₂‐Purinoceptors

1990 • 55 citations

Isolation and culture of cells derived from human cerebral microvessels

1987 • 54 citations

Purification and partial characterization of brain adenosine deaminase: Inhibition by purine compounds and by drugs

1988 • 51 citations

Adenosine Deaminase and [3H] Nitrobenzylthioinosine as Markers of Adenosine Metabolism and Transport in Central Purinergic Systems

1990 • 42 citations

Enhancement by purine nucleosides and nucleotides of serum‐induced DNA synthesis in quiescent 3T3 cells

1973 • 40 citations

Preparation and partial characterization of highly purified primary cultures of neurons and non-neuronal (glial) cells from embryonic chick cerebral hemispheres and several other regions of the nervous system

1982 • 29 citations

Some Properties of Isolated Endothelial Cells in Culture

1980 • 26 citations

Human cerebral endothelium: Isolation and characterization of cells derived from microvessels of non-neoplastic and malignant glial tissue

1990 • 21 citations

Purine nucleotides inhibit the binding of dl-[3H] 2-amino-4-phosphonobutyrate (dl-[3H] APB) to l-glutamate-sensitive sites on rat brain membranes

1986 • 20 citations

The effects of nucleotides on the response of the isolated guinea pig urinary bladder to nonadrenergic, noncholinergic nerve stimulation

1981 • 16 citations

Stimulation by transforming growth factor-β of epidermal growth factor-dependent growth of aged human fibroblasts: Recovery of high affinity EGF receptors and growth stimulation by EGF

1989 • 16 citations

Nerve trophic effects: Partial purification from chick embryo brains of proteins that stimulate protein synthesis in cultured newt blastemata

1981 • 14 citations

Adenosine Release

1990 • 13 citations

Extracellular ATP Is a Mitogen for 3T3, 3T6, A431, DDT₁‐MF2, BALB/MK, NIE‐115, and HFF Cells^a

1990 • 11 citations

Purification of a chick brain-derived growth factor by reversed-phase high-performance liquid chromatography

1987 • 9 citations

Modulation of response to adenosine in vascular smooth muscle cells cultured in defined medium

1991 • 8 citations

A low-molecular weight chick brain-derived growth factor is mitogenic for cultured astroglia from the chick embryo

1988 • 7 citations