Expression of 5-HT3 receptors in the rat gastrointestinal tract

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A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract

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The 5-HT3B subunit is a major determinant of serotonin-receptor function

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1995 • 535 citations

Neurochemical classification of myenteric neurons in the guinea-pig ileum

1996 • 484 citations

Review article: roles played by 5‐hydroxytryptamine in the physiology of the bowel

1999 • 463 citations

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1999 • 398 citations

c-kit-Dependent development of interstitial cells and electrical activity in the murine gastrointestinal tract

1995 • 392 citations

Improvement in pain and bowel function in female irritable bowel patients with alosetron, a 5‐HT₃ receptor antagonist

1999 • 381 citations

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1990 • 354 citations

The Pharmacological and Functional Characteristics of the Serotonin 5-HT3A Receptor Are Specifically Modified by a 5-HT3B Receptor Subunit

1999 • 278 citations

Cholecystokinin inhibits gastric motility and emptying via a capsaicin-sensitive vagal pathway in rats

1988 • 265 citations

Retracted: Intestinal serotonin acts as a paracrine substance to mediate vagal signal transmission evoked by luminal factors in the rat

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1997 • 225 citations

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1986 • 202 citations

The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors

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Distinct 5-HT receptors mediate the peristaltic reflex induced by mucosal stimuli in human and guinea pig intestine

1996 • 189 citations

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1994 • 183 citations

The 5-HT3 Receptor Channel

1995 • 180 citations

Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species.

1995 • 179 citations

Serotonin released from intestinal enterochromaffin cells mediates luminal non–cholecystokinin-stimulated pancreatic secretion in rats

2000 • 174 citations

GR 38032F (Ondansetron), a selective 5HT3 receptor antagonist, slows colonic transit in healthy man

1990 • 165 citations

Cellular sites of expression of the neurokinin‐1 receptor in the rat gastrointestinal tract

1995 • 155 citations

Cloning and fnctional expression of an apparent splice variant of the murine 5-HT3 receptor A subunit

1993 • 147 citations

Modulation by 5-HT3 and 5-HT4 receptors of the release of 5-hydroxytryptamine from the guinea-pig small intestine

1993 • 131 citations

Expression of Recombinant Homo-oligomeric 5-Hydroxytryptamine3 Receptors Provides New Insights into Their Maturation and Structure

1995 • 129 citations

Interstitial cells of Cajal as targets for pharmacological intervention in gastrointestinal motor disorders

1997 • 126 citations

Sensitivity to 5‐hydroxytryptamine in different afferent subpopulations within mesenteric nerves supplying the rat jejunum

1998 • 120 citations

III. Visceral afferent pathways: a source of new therapeutic targets for abdominal pain

2000 • 102 citations

Somatostatin 2A receptor is expressed by enteric neurons, and by interstitial cells of Cajal and enterochromaffin-like cells of the gastrointestinal tract

1997 • 100 citations

Activation of neurokinin 1 receptors on interstitial cells of Cajal of the guinea-pig small intestine by substance P

1998 • 99 citations

Evidence for Expression of Heteromeric Serotonin 5-HT3 Receptors in Rodents

2000 • 95 citations

5‐HT activates neural reflexes regulating secretion in the guinea‐pig colon

1997 • 94 citations

5-HT receptor subtypes outside the central nervous system. Roles in the physiology of the gut.

1990 • 90 citations

Molecular Cloning, Functional Expression, and Pharmacological Characterization of 5-Hydroxytryptamine₃ Receptor cDNA and Its Splice Variants from Guinea Pig

1998 • 90 citations

Expression of cholecystokinin a receptors in neurons innervating the rat stomach and intestine

1999 • 85 citations

Synaptic activation and properties of 5-hydroxytryptamine(3) receptors in myenteric neurons of guinea pig intestine.

1999 • 79 citations

Embryological origin of interstitial cells of Cajal

1999 • 77 citations

Electrophysiological studies of 5-hydroxytryptamine receptors on enteric neurons

1995 • 73 citations

Organization of the mouse 5-HT3 receptor gene and functional expression of two splice variants

1994 • 73 citations

Role of 5-hydroxytryptamine type 3 receptors in rat intestinal fluid and electrolyte secretion induced by cholera and Escherichia coli enterotoxins.

1995 • 65 citations

Partial cDNA cloning and NGF regulation of a rat 5-HT3 receptor subunit

1993 • 61 citations

Autoreceptors can modulate 5-hydroxytryptamine release from porcine and human small intestine in vitro

1998 • 60 citations

Effects of alosetron on gastrointestinal transit time and rectal sensation in patients with irritable bowel syndrome

2000 • 59 citations

Subpopulations of Gastric Myenteric Neurons Are Differentially Activated via Distinct Serotonin Receptors: Projection, Neurochemical Coding, and Functional Implications

1997 • 59 citations

Inhibitory innervation of colonic smooth muscle cells and interstitial cells of Cajal

1990 • 55 citations

Vasoactive intestinal peptide expression in enteric neurons is upregulated by both colchicine and axotomy

1996 • 53 citations

A monoclonal antibody to somatostatin with potent in vivo immunoneutralizing activity

1990 • 45 citations

The pharmacological properties of the novel selective 5‐HT₃ receptor antagonist, alosetron, and its effects on normal and perturbed small intestinal transit in the fasted rat

1999 • 41 citations

Monoclonal Antibody to VIP: Production, Characterization, Immunoneutralizing Activity, and Usefulness in Cytochemical Staining

1996 • 40 citations

Inhibition of gastric motility induced by intestinal glucose in awake rats: role of Na⁺‐glucose co‐transporter

1995 • 38 citations

Species differences in the immunoreactive patterns of calcitonin gene-related peptide in the pancreas

1992 • 38 citations

Organisation of the murine 5‐HT₃ receptor gene and assignment tohuman chromosome 11

1994 • 36 citations

Pharmacological characterization of the 5‐HT receptor‐mediated contraction in the mouse isolated ileum

2000 • 30 citations

Cloning, expression, and characterization of ferret 5-HT3 receptor subunit

2000 • 26 citations

Detection of 5-HT3R-A, a 5-HT3 receptor subunit, in submucosal and myenteric; ganglia of rat small intestine using in situ hybridization

1995 • 23 citations

Inward currents in neurons from newborn guinea pig intestine: mediation by 5-hydroxytryptamine type 3 receptors.

1999 • 21 citations

Vasoactive intestinal peptide expression in enteric neurons is upregulated by both colchicine and axotomy.

1996 • 15 citations