Back to search

Effects of alosetron on gastrointestinal transit time and rectal sensation in patients with irritable bowel syndrome

Data up to Jan 2025

Published2000
Citations59
References45

Total Citations Per Year

Abstract

References (45)

Functional bowel disorders and functional abdominal pain

1999 • 2,360 citations

Towards positive diagnosis of the irritable bowel.

1978 • 1,382 citations

Altered rectal perception is a biological marker of patients with irritable bowel syndrome

1995 • 991 citations

Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome

1973 • 833 citations

Tolerance for Rectosigmoid Distention in Irritable Bowel Syndrome

1990 • 599 citations

Irritable bowel syndrome: A technical review for practice guideline development

1997 • 585 citations

Repetitive sigmoid stimulation induces rectal hyperalgesia in patients with irritable bowel syndrome

1997 • 383 citations

Improvement in pain and bowel function in female irritable bowel patients with alosetron, a 5‐HT3 receptor antagonist

1999 • 381 citations

Irritable bowel syndrome: relationship of disorders in the transit of a single solid meal to symptom patterns.

1983 • 366 citations

Irritable bowel syndrome in office-based practice in the United States

1991 • 316 citations

Review article: irritable bowel syndrome

1997 • 300 citations

Relationship between impaired gastric emptying and abnormal gastrointestinal motility

1986 • 281 citations

Physiological variations in canine gastric tone measured by an electronic barostat

1985 • 257 citations

Human gastric emptying and colonic filling of solids characterized by a new method

1989 • 230 citations

Transit through the proximal colon influences stool weight in the irritable bowel syndrome

1992 • 223 citations

Transit of solids through the human colon: regional quantification in the unprepared bowel

1990 • 218 citations

Towards a less costly but accurate test of gastric emptying and small bowel transit

1991 • 203 citations

Reduction of rectal sensitivity and post‐prandial motility by granisetron, a 5 HT3‐receptor antagonist, in patients with irritable bowel syndrome

1993 • 186 citations

Review article: 5‐hydroxytryptamine agonists and antagonists in the modulation of gastrointestinal motility and sensation: clinical implications

1992 • 174 citations

Adrenergic modulation of human colonic motor and sensory function

1997 • 173 citations

Psychosensory modulation of colonic sensation in the human transverse and sigmoid colon

1995 • 167 citations

GR 38032F (Ondansetron), a selective 5HT3 receptor antagonist, slows colonic transit in healthy man

1990 • 165 citations

Visceral perception in irritable bowel syndrome

1995 • 157 citations

The κ agonist fedotozine relieves hypersensitivity to colonic distention in patients with irritable bowel syndrome

1999 • 157 citations

Rectal tone, distensibility, and perception: reproducibility and response to different distensions

1998 • 153 citations

Serotonergic mediation of postprandial colonic tonic and phasic responses in humans.

1994 • 138 citations

Towards a relatively inexpensive, noninvasive, accurate test for colonic motility disorders

1992 • 122 citations

Colonic transit scintigraphy labeled activated charcoal compared with ion exchange pellets.

1997 • 114 citations

Colonic transit in man is slowed by ondansetron (GR38032F), a selective 5‐hydroxytryptamine receptor (type 3) antagonist

1990 • 108 citations

Selective 5-Hydroxytryptamine Type 3 Receptor Antagonism With Ondansetron as Treatment for Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Study

1992 • 106 citations

Selective 5‐hydroxytryptamine antagonism: a role in irritable bowel syndrome and functional dyspepsia?

1996 • 97 citations

The effects of granisetron, ICS 205–930 and ondansetron on the visceral pain reflex induced by duodenal distension

1990 • 97 citations

The Non-Antiemetic Uses of Serotonin 5-HT3 Receptor Antagonists

1997 • 97 citations

Modification of Visceral Sensitivity and Pain in Irritable Bowel Syndrome by 5-HT<sub>3</sub> Antagonism (Ondansetron)

1996 • 95 citations

Jejunal sensorimotor dysfunction in irritable bowel syndrome: Clinical and psychosocial features

1996 • 87 citations

Variations in muscle tone of the human rectum: recordings with an electromechanical barostat

1991 • 85 citations

Pharmacological modulation of rectal tone alters perception of distention in humans.

1997 • 71 citations

In vivo effects of the 5‐HT3 antagonist alosetron on basal and cholera toxin‐induced secretion in the human jejunum: a segmental perfusion study

1997 • 67 citations

Manovolumetry: a new method for investigation of anorectal function.

1988 • 65 citations

Alosetron does not affect the visceral perception of gastric distension in healthy subjects

1994 • 60 citations

Central modulation of rectal distension-induced blood pressure changes by alosetron, a 5-HT3 receptor antagonist.

1999 • 52 citations

Medium term effects of a new 5HT3 antagonist, alosetron, in patients with carcinoid diarrhoea

1998 • 47 citations

Hyperventilation alters colonic motor and sensory function: Effects and mechanisms in humans

1996 • 25 citations

α2-Adrenergic modulation of colonic tone during hyperventilation

1997 • 9 citations

Autonomic control of colonic tone and the cold pressore test.

1996 • 6 citations

Cited By (0)

Loading...