α-RgIA, a Novel Conotoxin That Blocks the α9α10 nAChR: Structure and Identification of Key Receptor-Binding Residues

The PyMOL Molecular Graphics System

2002 • 18,218 citations

MOLMOL: A program for display and analysis of macromolecular structures

1996 • 7,169 citations

AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR

1996 • 5,190 citations

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

1992 • 3,627 citations

The Xplor-NIH NMR molecular structure determination package

2003 • 2,345 citations

The Protein Data Bank

2002 • 2,325 citations

Pure absorption gradient enhanced heteronuclear single quantum correlation spectroscopy with improved sensitivity

1992 • 2,231 citations

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

2001 • 1,736 citations

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

1995 • 1,618 citations

Structure and gating mechanism of the acetylcholine receptor pore

2003 • 1,261 citations

Sensitivity improvement in proton-detected two-dimensional heteronuclear correlation NMR spectroscopy

1991 • 931 citations

ConusVenoms: A Rich Source of Novel Ion Channel-Targeted Peptides

2004 • 884 citations

Nicotine and Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studied in AChBP Crystal Structures

2004 • 778 citations

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

2005 • 617 citations

A glia-derived acetylcholine-binding protein that modulates synaptic transmission

2001 • 564 citations

A New α-Conotoxin Which Targets α3β2 Nicotinic Acetylcholine Receptors

1996 • 479 citations

A PFG NMR experiment for accurate diffusion and flow studies in the presence of eddy currents

1991 • 469 citations

Protein NMR structure determination with automated NOE-identification in the NOESY spectra using the new software ATNOS.

2002 • 469 citations

‘Random coil’ 1H chemical shifts obtained as a function of temperature and trifluoroethanol concentration for the peptide series GGXGG

1995 • 467 citations

A relational database for sequence-specific protein NMR data

1991 • 357 citations

Neuronal nicotinic receptors: Molecular organization and regulations

1995 • 254 citations

Molecular mechanism for analgesia involving specific antagonism of α9α10 nicotinic acetylcholine receptors

2006 • 225 citations

PREDITOR: a web server for predicting protein torsion angle restraints

2006 • 189 citations

Structural determinants of selective α-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP

2006 • 189 citations

α-RgIA: A Novel Conotoxin That Specifically and Potently Blocks the α9α10 nAChR^,

2006 • 164 citations

Conotoxins down under

2006 • 158 citations

Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor

2006 • 129 citations

Characterization of the human nicotinic acetylcholine receptor subunit alpha (α) 9 (CHRNA9) and alpha (α) 10 (CHRNA10) in lymphocytes

2004 • 129 citations

Measuring protein self-association using pulsed-field-gradient NMR spectroscopy: Application to myosin light chain 2

1995 • 114 citations

Single-Residue Alteration in α-Conotoxin PnIA Switches Its nAChR Subtype Selectivity

1999 • 111 citations

α‐Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes

2004 • 109 citations

Peptide self-association in aqueous trifluoroethanol monitored by pulsed field gradient NMR diffusion measurements.

2000 • 100 citations

α-Conotoxins ImI and ImII

2003 • 99 citations

α-Conotoxins ImI and ImII Target Distinct Regions of the Human α7 Nicotinic Acetylcholine Receptor and Distinguish Human Nicotinic Receptor Subtypes

2004 • 84 citations

Structural Elements in α-Conotoxin ImI Essential for Binding to Neuronal α7 Receptors

1998 • 83 citations

α-Conotoxins as selective probes for nicotinic acetylcholine receptor subclasses

2005 • 81 citations

Pairwise Interactions between Neuronal α7Acetylcholine Receptors and α-Conotoxin ImI

1999 • 70 citations

NMR spatial structure of α‐conotoxin ImI reveals a common scaffold in snail and snake toxins recognizing neuronal nicotinic acetylcholine receptors¹

1999 • 66 citations

Targeting the α₉α₁₀nicotinic acetylcholine receptor to treat severe pain

2007 • 63 citations

Identification of Residues in the Neuronal α7Acetylcholine Receptor That Confer Selectivity for Conotoxin ImI

1998 • 61 citations

Solution Structure of α-Conotoxin ImI by¹H Nuclear Magnetic Resonance

1999 • 60 citations

NMR Solution Structure of α-Conotoxin ImI and Comparison to Other Conotoxins Specific for Neuronal Nicotinic Acetylcholine Receptors^,

1999 • 50 citations

Minimal conformation of the ±‐conotoxin ImI for the ±7 neuronalnicotinic acetylcholine receptor recognition: correlated CD, NMR and binding studies

1999 • 47 citations

Mimotopes of Apical Membrane Antigen 1: Structures of Phage-Derived Peptides Recognized by the Inhibitory Monoclonal Antibody 4G2dc1 and Design of a More Active Analogue

2006 • 13 citations