Molecular mechanism for analgesia involving specific antagonism of α9α10 nicotinic acetylcholine receptors

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

1988 • 5,129 citations

Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation

2002 • 2,972 citations

A method for measurement of analgesic activity on inflamed tissue.

1957 • 1,558 citations

Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway

2005 • 1,010 citations

Neuronal nicotinic receptors: from structure to pathology

2004 • 941 citations

α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells

1994 • 869 citations

α10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells

2001 • 671 citations

The Vagus Nerve and Nicotinic Receptors Modulate Experimental Pancreatitis Severity in Mice

2006 • 363 citations

The lymphocytic cholinergic system and its contribution to the regulation of immune activity

2003 • 317 citations

T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats

2004 • 286 citations

Depletion of macrophages reduces axonal degeneration and hyperalgesia following nerve injury

2000 • 237 citations

Macrophage Response to Peripheral Nerve Injury: The Quantitative Contribution of Resident and Hematogenous Macrophages

2003 • 229 citations

A Novel Human Nicotinic Receptor Subunit, α10, That Confers Functionality to the α9-Subunit

2002 • 203 citations

Alpha-conotoxin Vc1.1 alleviates neuropathic pain and accelerates functional recovery of injured neurones

2005 • 178 citations

A Novel α-Conotoxin Identified by Gene Sequencing Is Active in Suppressing the Vascular Response to Selective Stimulation of Sensory Nerves in Vivo

2003 • 175 citations

α-RgIA: A Novel Conotoxin That Specifically and Potently Blocks the α9α10 nAChR^,

2006 • 164 citations

The contribution of training to sensitivity in the nociceptive paw-withdrawal test

1989 • 163 citations

Caught in the Act:In VivoMapping of Macrophage Infiltration in Nerve Injury by Magnetic Resonance Imaging

2003 • 150 citations

Central role of α7 nicotinic receptor in differentiation of the stratified squamous epithelium

2002 • 140 citations

The Synthesis, Structural Characterization, and Receptor Specificity of the α-Conotoxin Vc1.1

2006 • 130 citations

Characterization of the human nicotinic acetylcholine receptor subunit alpha (α) 9 (CHRNA9) and alpha (α) 10 (CHRNA10) in lymphocytes

2004 • 129 citations

Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor

2006 • 129 citations

Coexpression of α9 and α10 nicotinic acetylcholine receptors in rat dorsal root ganglion neurons

2002 • 118 citations

α-Conotoxin BuIA, a Novel Peptide from Conus bullatus, Distinguishes among Neuronal Nicotinic Acetylcholine Receptors

2004 • 113 citations

Distinct functional types of macrophage in dorsal root ganglia and spinal nerves proximal to sciatic and spinal nerve transections in the rat

2003 • 106 citations

Antinociceptive effects of choline against acute and inflammatory pain

2005 • 95 citations

Nicotinic Acetylcholine Receptor Subunits and Associated Proteins inHuman Sperm

2005 • 77 citations

Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist.

1999 • 66 citations

Nicotinic cholinergic receptors: potential targets for inflammatory pain relief

1999 • 65 citations

Medications for neuropathic pain: current trends

2006 • 58 citations

Differences between the antinociceptive effects of the cholinergic channel activators A-85380 and (+/-)-epibatidine in rats.

1998 • 58 citations

Antihyperalgesic activity of epibatidine in the formalin model of facial pain

2001 • 47 citations