Comparative affects of plasmid‐encoded interleukin 12 and interleukin 18 on the protective efficacy of DNA vaccination against Mycobacterium tuberculosis

Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12

2000 • 2,755 citations

An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.

1993 • 2,410 citations

Disseminated tuberculosis in interferon gamma gene-disrupted mice.

1993 • 1,982 citations

Variation in protection by BCG: implications of and for heterologous immunity

1995 • 1,347 citations

IGIF Does Not Drive Th1 Development but Synergizes with IL-12 for Interferon-γ Production and Activates IRAK and NFκB

1997 • 726 citations

Interleukin 12 (IL-12) Is Crucial to the Development of Protective Immunity in Mice Intravenously Infected with Mycobacterium tuberculosis

1997 • 696 citations

Immunogenicity and protective efficacy of a tuberculosis DNA vaccine

1996 • 629 citations

Interferon‐γ‐inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin‐12 for interferon‐γ production

1996 • 606 citations

Vaccination against tuberculosis by DNA injection

1996 • 513 citations

Therapy of tuberculosis in mice by DNA vaccination

1999 • 488 citations

A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma.

1997 • 325 citations

Differential Protective Efficacy of DNA Vaccines Expressing Secreted Proteins ofMycobacterium tuberculosis

1999 • 292 citations

Role of Interleukin-18 (IL-18) in Mycobacterial Infection in IL-18-Gene-Disrupted Mice

1999 • 249 citations

IL-12 Gene as a DNA Vaccine Adjuvant in a Herpes Mouse Model: IL-12 Enhances Th1-Type CD4+ T Cell-Mediated Protective Immunity Against Herpes Simplex Virus-2 Challenge

1999 • 193 citations

CpG Oligodeoxynucleotides and Interleukin-12 Improve the Efficacy ofMycobacterium bovisBCG Vaccination in Mice Challenged withM. tuberculosis

2000 • 117 citations

Co‐immunization with DNA vaccines expressing granulocyte–macrophage colony‐stimulating factor and mycobacterial secreted proteins enhances T‐cell immunity, but not protective efficacy against Mycobacterium tuberculosis

1999 • 66 citations

Coexpression of Interleukin-12 Chains by a Self-Splicing Vector Increases the Protective Cellular Immune Response of DNA andMycobacterium bovisBCG Vaccines againstMycobacterium tuberculosis

2002 • 52 citations

Production of Interleukin-12 as a Self-Processing 2A Polypeptide

1999 • 45 citations

In Vivo Immunomodulation Following Intradermal Injection with DNA Encoding IL-18

1999 • 44 citations

Induction of in vivo resistance to Mycobacterium avium infection by intramuscular injection with DNA encoding interleukin‐18

2001 • 25 citations

The Global Control of Tuberculosis: What are the Prospects?

2001 • 22 citations

Mechanism of Protection against Influenza A Virus by DNA Vaccine Encoding the Hemagglutinin Gene

2000 • 15 citations

Immunoprophylaxis against Mycobacterium leprae infection with subunit vaccines.

2000 • 10 citations