Severe developmental defects in Dictyostelium null mutants for actin-binding proteins

Growth of myxamoebae of the cellular slime mould Dictyostelium discoideum in axenic culture

1970 • 1,142 citations

Dictyostelium discoideum: A Developmental System

1977 • 505 citations

Dictyostelium discoideum: A developmental system

1975 • 401 citations

The Cellular Slime Molds.

1967 • 362 citations

Coronin involved in phagocytosis: Dynamics of particle-induced relocalization visualized by a green fluorescent protein tag

1995 • 353 citations

Elongation factor 1α, translation and the cytoskeleton

1995 • 273 citations

MOLECULAR GENETICS OF SIGNAL TRANSDUCTION IN DICTYOSTELIUM

1996 • 261 citations

Thinking about genetic redundancy

1993 • 244 citations

CYCLIC AMP AND OTHER SIGNALS CONTROLLING CELL DEVELOPMENT AND DIFFERENTIATION IN DICTYOSTELIUM

1987 • 240 citations

Dictyostelium amoebae that lack G-actin-sequestering profilins show defects in F-actin content, cytokinesis, and development

1994 • 233 citations

Cortexillins, Major Determinants of Cell Shape and Size, Are Actin-Bundling Proteins with a Parallel Coiled-Coil Tail

1996 • 175 citations

Capping protein levels influence actin assembly and cell motility in dictyostelium

1995 • 171 citations

The role of the cortical cytoskeleton: F-actin crosslinking proteins protect against osmotic stress, ensure cell size, cell shape and motility, and contribute to phagocytosis and development

1996 • 161 citations

Redundancy in the microfilament system: Abnormal development of dictyostelium cells lacking two F-actin cross-linking proteins

1992 • 151 citations

Generation and characterization of Dictyostelium cells deficient in a myosin I heavy chain isoform.

1990 • 137 citations

G Protein β Subunit–null Mutants Are Impaired in Phagocytosis and Chemotaxis Due to Inappropriate Regulation of the Actin Cytoskeleton

1998 • 132 citations

The actin-binding protein comitin (p24) is a component of the Golgi apparatus.

1993 • 106 citations

A Dictyostelium mutant deficient in severin, an F-actin fragmenting protein, shows normal motility and chemotaxis.

1989 • 100 citations

Hisactophilin, a histidine-rich actin-binding protein from Dictyostelium discoideum

1989 • 94 citations

Patterns of free calcium in multicellular stages of Dictyostelium expressing jellyfish apoaequorin

1995 • 77 citations

Mutants lacking myosin II cannot resist forces generated during multicellular morphogenesis

1995 • 74 citations

Detection of subtle phenotypes: The case of the cell adhesion molecule csA in Dictyostelium

1998 • 70 citations

Three actin cross-linking proteins, the 34 kDa actin-bundling protein, α-actinin and gelation factor (ABP-120), have both unique and redundant roles in the growth and development of Dictyostelium

1999 • 68 citations

Re-expression of ABP-120 rescues cytoskeletal, motility, and phagocytosis defects of ABP-120- Dictyostelium mutants.

1996 • 65 citations

Linking microfilaments to intracellular membranes: the actin-binding and vesicle-associated protein comitin exhibits a mannose-specific lectin activity.

1996 • 64 citations

The in vivo role of annexin VII (synexin): characterization of an annexin VII deficient Dictyostelium mutant indicates an involvement in Ca2+-regulated processes

1995 • 63 citations

TheDictyostelium cytoskeleton

1995 • 59 citations

Interaptin, an Actin-binding Protein of the α-Actinin Superfamily in Dictyostelium discoideum, Is Developmentally and cAMP-regulated and Associates with Intracellular Membrane Compartments

1998 • 57 citations

Ponticulin is the major high affinity link between the plasma membrane and the cortical actin network in Dictyostelium.

1994 • 56 citations

High levels of actin tyrosine phosphorylation: Correlation with the dormant state of Dictyostelium spores

1998 • 55 citations

Mechanical perturbation elicits a phenotypic difference between Dictyostelium wild-type cells and cytoskeletal mutants

1996 • 52 citations

Dictyostelium discoideum cells lacking the 34,000-dalton actin-binding protein can grow, locomote, and develop, but exhibit defects in regulation of cell structure and movement: a case of partial redundancy.

1996 • 46 citations

Cell adhesion in the life cycle ofDictyostelium

1995 • 39 citations

Structure/function studies on the pH-dependent actin-binding protein hisactophilin in Dictyostelium mutants

1996 • 38 citations

The role of Ca2+ during spore germination in Dictyostelium: autoactivation is mediated by the mobilization of Ca2+ while amoebal emergence requires entry of external Ca2+

1995 • 21 citations

Cell differentiation in the absence of intracellular and extracellular cyclic AMP pulses in Dictyostelium discoideum

1987 • 20 citations