Thinking about genetic redundancy

The Clonal Evolution of Tumor Cell Populations

1976 • 6,310 citations

A novel multigene family may encode odorant receptors: A molecular basis for odor recognition

1991 • 4,793 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

The Age Distribution of Cancer and a Multi-stage Theory of Carcinogenesis

1954 • 1,475 citations

Repeated Genes in Eukaryotes

1980 • 1,383 citations

Mutation selection and the natural history of cancer

2006 • 1,185 citations

Initiation of sporulation in B. subtilis is controlled by a multicomponent phosphorelay

1991 • 870 citations

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo

1987 • 796 citations

An Insulin-Stimulated Protein Kinase Similar to Yeast Kinases Involved in Cell Cycle Control

1990 • 701 citations

Chemosensory neurons with overlapping functions direct chemotaxis to multiple chemicals in C. elegans

1991 • 691 citations

glp-1 Is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans

1987 • 684 citations

The lin-12 locus specifies cell fates in caenorhabditis elegans

1983 • 598 citations

An essential G1 function for cyclin-like proteins in yeast

1989 • 574 citations

DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae.

1988 • 445 citations

FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation

1990 • 437 citations

Subtle Cerebellar Phenotype in Mice Homozygous for a Targeted Deletion of the En-2 Homeobox

1991 • 416 citations

Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly.

1992 • 401 citations

Cell cycle control of the yeast HO gene: Cis- and Trans-acting regulators

1987 • 392 citations

The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast

1991 • 354 citations

Kinesin-related proteins required for assembly of the mitotic spindle.

1992 • 347 citations

glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins

1989 • 345 citations

Genetic Control of Differentiation of the Caenorhabditis elegans Touch Receptor Neurons

1989 • 344 citations

The glp-1 locus and cellular interactions in early C. elegans embryos

1987 • 335 citations

A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae

1989 • 298 citations

Evidence for parallel processing of sensory information controlling dauer formation in Caenorhabditis elegans.

1993 • 262 citations

The organization and amplification of two chromosomal domains containing drosophila chorion genes

1981 • 260 citations

Two homologous regulatory genes, lin-12 and glp-1, have overlapping functions

1991 • 252 citations

Synthetic enhancement in gene interaction: a genetic tool come of age

1993 • 234 citations

unc-93(e1500): A BEHAVIORAL MUTANT OF CAENORHABDITIS ELEGANS THAT DEFINES A GENE WITH A WILD-TYPE NULL PHENOTYPE

1980 • 190 citations

MOLECULAR GENETICS OF HUMAN VISUAL PIGMENTS

1992 • 183 citations

Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2.

1992 • 105 citations

Different G1 cyclins control the timing of cell cycle commitment in mother and daughter cells of the budding yeast S. cerevisiae

1992 • 101 citations

A SECOND CLASS OF ACETYLCHOLINESTERASE-DEFICIENT MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS

1981 • 98 citations

Retinoblastoma and the progression of tumor genetics

1988 • 80 citations

Perturbations of Drosophila alpha-actinin cause muscle paralysis, weakness, and atrophy but do not confer obvious nonmuscle phenotypes.

1992 • 72 citations

The Caenorhabditis elegans gene lin-10 is broadly expressed while required specifically for the determination of vulval cell fates.

1990 • 71 citations

Functional redundancy in mitotic force generation.

1993 • 60 citations

Induction of Neuronal Branching in Caenorhabditis elegans

1983 • 58 citations

Cell interactions involved in development of the bilaterally symmetrical intestinal valve cells during embryogenesis in Caenorhabditis elegans

1992 • 58 citations

Genetic analysis of a Drosophila microtubule-associated protein.

1992 • 40 citations

SCM4, a gene that suppresses mutant cdc4 function in budding yeast

1992 • 13 citations

CLN3 functions in both daughter and mother cells of S. cerevisiae

1993 • 6 citations