Role of peptide growth factors in the prostate: A review

Studies on Prostatic Cancer. I. The Effect of Castration, of Estrogen and of Androgen Injection on Serum Phosphatases in Metastatic Carcinoma of the Prostate

1941 • 3,235 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Epidermal Growth Factor

1979 • 2,964 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

Epidermal growth factor.

1990 • 1,645 citations

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

1986 • 1,617 citations

STUDIES ON PROSTATIC CANCER

1941 • 1,498 citations

Structural Characterization and Biological Functions of Fibroblast Growth Factor

1987 • 1,299 citations

Structural and Functional Diversity in the FGf Receptor Multigene Family

1992 • 1,262 citations

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor

1986 • 1,226 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

Recent developments in the cell biology of basic fibroblast growth factor.

1989 • 1,049 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Human KGF is FGF-Related with Properties of a Paracrine Effector of Epithelial Cell Growth

1989 • 989 citations

Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors.

1987 • 895 citations

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

1990 • 753 citations

Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur.

1990 • 734 citations

TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1990 • 714 citations

Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development.

1991 • 677 citations

The TGF-β family of growth and differentiation factors

1987 • 675 citations

Normal Histology of the Prostate

1988 • 658 citations

Receptors for the TGF-β family

1992 • 638 citations

Expression cloning and characterization of the TGF-β type III receptor

1991 • 638 citations

Human basic fibroblast growth factor: nucleotide sequence and genomic organization.

1986 • 604 citations

Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer.

1989 • 592 citations

Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane.

1990 • 470 citations

Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro.

1990 • 466 citations

Development of mammary hyperplasia and neoplasia in MMTV-TGFα transgenic mice

1990 • 447 citations

Complexity of FGF receptors: genetic basis for structural diversity and functional specificity

1992 • 441 citations

Transforming growth factor-alpha. A model for membrane-anchored growth factors.

1990 • 430 citations

Expression of Transforming Growth Factor-β in the Rat Ventral Prostate during Castration-Induced Programmed Cell Death

1989 • 417 citations

A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance.

1990 • 409 citations

Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential.

1990 • 398 citations

Immunosuppression and transforming growth factor-beta in glioblastoma. Preferential production of transforming growth factor-beta 2.

1989 • 391 citations

Basic fibroblast growth factor fused to a signal peptide transforms cells

1988 • 379 citations

Regulation of intestinal epithelial cell growth by transforming growth factor type beta.

1989 • 341 citations

Role of epidermal growth factor in carcinogenesis.

1986 • 330 citations

Direct mitogenic effects of insulin, epidermal growth factor, glucocorticoid, cholera toxin, unknown pituitary factors and possibly prolactin, but not androgen, on normal rat prostate epithelial cells in serum-free, primary cell culture.

1984 • 315 citations

Activation of the bone-derived latent TGF beta complex by isolated osteoclasts

1989 • 281 citations

Normal and abnormal development of the male urogenital tract. Role of androgens, mesenchymal-epithelial interactions, and growth factors.

1992 • 279 citations

The int-2 gene product acts as an epithelial growth factor in transgenic mice.

1990 • 263 citations

The prostate gland : morphology and pathobiology

1988 • 246 citations

Transforming growth factor-beta 1 overproduction in prostate cancer: effects on growth in vivo and in vitro.

1992 • 242 citations

Immunocytochemical localization of human epidermal growth factor/urogastrone in several human tissues.

1985 • 235 citations

Human keratinocyte growth factor activity on proliferation and differentiation of human keratinocytes: Differentiation response distinguishes KGF from EGF family

1990 • 228 citations

Complex regulation of transforming growth factor beta 1, beta 2, and beta 3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors beta 1 and beta 2.

1989 • 221 citations

Effect of Transforming Growth Factor-β¹on Proliferation and Death of Rat Prostatic Cells*

1990 • 218 citations

Human transforming growth factor type .beta.2: production by a prostatic adenocarcinoma cell line, purification, and initial characterization

1987 • 204 citations

Transforming Growth Factor-β2: cDNA Cloning and Sequence Analysis

1988 • 200 citations

Transforming Growth Factor-β Stimulates Bone Matrix Apposition and Bone Cell Replication in Cultured Fetal Rat Calvariae*

1990 • 192 citations

Normal and Abnormal Development of the Male Urogenital Tract

1992 • 191 citations

Characterization of the receptor for keratinocyte growth factor. Evidence for multiple fibroblast growth factor receptors.

1990 • 187 citations

Increased expression of genes for basic fibroblast growth factor and transforming growth factor type β2 in human benign prostatic hyperplasia

1990 • 181 citations

Identification of a Cellular Receptor for Transforming Growth Factor-β in Rat Ventral Prostate and Its Negative Regulation by Androgens*

1988 • 178 citations

Association of transforming growth factor-β1 with prostate cancer: An immunohistochemical study

1993 • 170 citations

Prostatic Epidermal Growth Factor Receptors and Their Regulation by Androgens*

1987 • 167 citations

Differential effects of transforming growth factor β on human prostate cancer cells in vitro

1989 • 166 citations

Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice.

1989 • 164 citations

Modulation of the Immune Response by Transforming Growth Factor Beta

1992 • 151 citations

Transformation of mouse BALB/c 3T3 cells with human basic fibroblast growth factor cDNA.

1988 • 150 citations

3 Fibroblast Growth Factor and Its Involvement in Developmental Processes

1990 • 148 citations

Epidermal growth factor stimulates the synthesis of its own receptor in a human breast cancer cell line.

1986 • 145 citations

Role of transforming growth factor ‐α in human prostate cancer cell growth

1989 • 142 citations

The glioblastoma‐derived T‐cell suppressor factor/transforming growth factor beta₂ inhibits the generation of lymphokineactivated killer (LAK) cells

1988 • 131 citations

Heparin-binding growth factor gene expression and receptor characteristics in normal rat prostate and two transplantable rat prostate tumors.

1989 • 127 citations

Transforming growth factor‐α

1990 • 126 citations

The glioblastoma‐derived t cell suppressor factor/ transforming growth factor‐β2 inhibits t cell growth without affecting the interaction of interleukin 2 with its receptor

1988 • 123 citations

Production of epidermal growth factor and transforming growth factor‐α by the androgen‐responsive LNCaP human prostate cancer cell line

1990 • 122 citations

Transforming Growth Factor

2008 • 121 citations

Growth factors and oncogenes in prostate cancer.

1990 • 115 citations

Concentrations of Epidermal Growth Factor, Nerve Growth Factor, and Submandibular Gland Renin in Male and Female Mouse Tissue and Fluids*

1979 • 110 citations

Different hormonal requirements for androgen-independent growth of normal and tumor epithelial cells from rat prostate

1987 • 105 citations

4 Transforming Growth Factor-β and Its Actions on Cellular Growth and Differentiation

1990 • 105 citations

Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-alpha. Characterization of mammary gland and skin proliferations.

1992 • 105 citations

Cultured human prostate‐derived fibroblasts produce a factor that stimulates their growth with properties indistinguishable from basic fibroblast growth factor

1989 • 101 citations

Transforming growth factor beta 1 regulates production of acute-phase proteins.

1990 • 96 citations

Epidermal Growth Factor Receptor mRNA Levels in Human Prostatic Tumors and Cell Lines

1990 • 94 citations

Transforming growth factor-beta 1 overproduction in prostate cancer: effects on growth in vivo and in vitro

1992 • 91 citations

Molecular cloning and characterization of the human and porcine transforming growth factor-β type III receptors

1992 • 85 citations

Heparin-binding growth factor/prostatropin attenuates inhibition of rat prostate tumor epithelial cell growth by transforming growth factor type beta

1988 • 80 citations

Expression of basic fibroblast growth factor mRNA in benign prostatic hyperplasia and prostatic carcinoma

1988 • 80 citations

Epidermal growth factor and transforming growth factor-alpha in the development of epithelial-mesenchymal organs of the mouse.

1990 • 77 citations

Epidermal Growth Factor and Prostatic Carcinoma: An Immunohistochemical Study

1988 • 75 citations

Urogastrone–epidermal growth factor concentrations in prostatic fluid of normal individuals and patients with benign prostatic hypertrophy

1986 • 74 citations

Gene activity during the early phase of androgen-stimulated rat prostate regrowth.

1989 • 72 citations

Differential Immunoreactivity of Epidermal Growth Factor Receptor in Benign, Dysplastic and Malignant Prostatic Tissues

1993 • 71 citations

Transforming growth factor β1 as a biomarker for prostate cancer

1992 • 71 citations

Epidermal growth factor receptors in human prostate cancer: correlation with histological differentiation of the tumour

1989 • 70 citations

Characterization of Growth Factors Derived from the Rat Ventral Prostate

1988 • 67 citations

Inhibitory Effects of the Bone-Derived Growth Factors Osteoinductive Factor and Transforming Growth Factor-β on Isolated Osteoclasts*

1990 • 64 citations

Androgens modulate epidermal growth factor receptor levels in the rat ventral prostate

1988 • 62 citations

Elevated Transforming Growth Factor-β 1 and β3 mRNA Levels are Associated withras+myc-induced Carcinomas in Reconstituted Mouse Prostate: Evidence for a Paracrine Role during Progression

1991 • 62 citations

Androgens and transforming growth factor β modulate the growth response to epidermal growth factor in human prostatic tumor cells (LNCaP)

1988 • 61 citations

2 Epidermal Growth Factor and Transforming Growth Factor-α in the Development of Epithelial—Mesenchymal Organs of the Mouse

1990 • 59 citations

Benign Prostatic Hyperplasia In A Transgenic Mouse: A New Hormonally Sensitive Investigatory Model

1993 • 55 citations

Androgenic regulation of epidermal growth factor in the mouse ventral prostate.

1988 • 54 citations

Heparin‐binding growth factor isolated from human prostatic extracts

1988 • 53 citations

Heterogeneity of Latent Transforming Growth Factor-β Isolated from Bone Matrix Proteins*

1990 • 47 citations

Production and significance of TGF-β in AT-3 metastatic cell line established from the Dunning rat prostatic adenocarcinoma

1990 • 43 citations

Growth Factors in the Prostate

1987 • 41 citations

Exocrine secretion of epidermal growth factor by the rat prostate: Effect of adrenergic agents, cholinergic agents, and vasoactive intestinal peptide

1988 • 40 citations

Evidence for an Organ- and Sex-Specific Role of Basic Fibroblast Growth Factor in the Development of the Fetal Mammalian Reproductive Tract*

1991 • 34 citations

Isolation of a prostate carcinoma cell proliferation-inhibiting factor from human seminal plasma and its similarity to transforming growth factor beta.

1992 • 34 citations

The Partial Dependency of Human Prostatic Growth Factor on Steroid Hormones in Stimulating Thymidine Incorporation into Dna

1987 • 32 citations

Rat Prostate Cancer Cells Contain Functional Receptors for Transforming Growth Factorβ*

1990 • 31 citations

Potential Role of HBGF (FGF) and TGF-Beta on Prostate Growth

1992 • 21 citations

The mouse int-2 gene exhibits basic fibroblast growth factor activity in a basic fibroblast growth factor-responsive cell line.

1990 • 21 citations

Localization of Basic Fibroblast Growth Factor (bFGF) in a Metastatic Cell Line (AT-3) Established from the Dunning Prostatic Carcinoma of Rat: Application of a Specific Monoclonal Antibody

1992 • 13 citations

A form of basic fibroblast growth factor is secreted into the adluminal fluid of the rat coagulating gland

1989 • 9 citations

Molecular mechanisms in cellular growth and differentiation

1992 • 2 citations

Control of Cell Proliferation by Transforming Growth Factors

1991 • 2 citations