Control of Cell Proliferation by Transforming Growth Factors

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

Growth Factors and Cancer

1991 • 2,044 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Growth factors from murine sarcoma virus-transformed cells.

1978 • 1,457 citations

Autocrine Secretion and Malignant Transformation of Cells

1980 • 1,370 citations

Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

1987 • 1,243 citations

Isolation of the bovine and human genes for müllerian inhibiting substance and expression of the human gene in animal cells

1986 • 997 citations

Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium.

1988 • 962 citations

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

1981 • 925 citations

Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.

1980 • 892 citations

Human transforming growth factor-α: Precursor structure and expression in E. coli

1984 • 888 citations

Production and auto-induction of transforming growth factor-α in human keratinocytes

1987 • 870 citations

Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta.

1987 • 791 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

1987 • 756 citations

A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β

1987 • 747 citations

Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-beta.

1987 • 736 citations

Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-β

1985 • 722 citations

The transforming growth factor-β system, a complex pattern of cross-reactive ligands and receptors

1987 • 710 citations

The TGF-β family of growth and differentiation factors

1987 • 675 citations

Rat Transforming Growth Factor Type 1: Structure and Relation to Epidermal Growth Factor

1984 • 666 citations

Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium.

1986 • 559 citations

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

1986 • 541 citations

Transforming growth factor production by chemically transformed cells.

1981 • 506 citations

The murine transforming growth factor-beta precursor.

1986 • 492 citations

Characterization of a membrane receptor for transforming growth factor-beta in normal rat kidney fibroblasts.

1984 • 477 citations

Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts.

1987 • 467 citations

Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta.

1986 • 443 citations

Integrated control of growth and differentiation of normal human prokeratinocytes cultured in serum‐free medium: Clonal analyses, growth kinetics, and cell cycle studies

1984 • 414 citations

Two forms of transforming growth factor-β distinguished by multipotential haematopoietic progenitor cells

1987 • 407 citations

Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type alpha and type beta transforming growth factors.

1983 • 381 citations

Cellular receptors for type beta transforming growth factor. Ligand binding and affinity labeling in human and rodent cell lines.

1985 • 344 citations

Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.

1986 • 339 citations

T cell suppressor factor from human glioblastoma cells is a 12.5-kd protein closely related to transforming growth factor-beta.

1987 • 337 citations

Normal embryo fibroblasts release transforming growth factors in a latent form

1984 • 336 citations

Serum contains a platelet-derived transforming growth factor.

1982 • 330 citations

Different transforming growth factor-α species are derived from a glycosylated and palmitoylated transmembrane precursor

1987 • 264 citations

Transforming growth factor‐α: Structure and biological activities

1986 • 250 citations

β-Transforming Growth Factor is stored in human blood platelets as a latent high molecular weight complex

1986 • 241 citations

Type 1 Transforming Growth Factor Beta: Amplified Expression and Secretion of Mature and Precursor Polypeptides in Chinese Hamster Ovary Cells

1987 • 224 citations

Specific binding to cultured cells of 125I-labeled type beta transforming growth factor from human platelets.

1984 • 212 citations

Inhibin and beta type transforming growth factor (TGFβ) have opposite modulating effects on the follicle stimulating hormone (FSH)-induced aromatase activity of cultured rat granulosa cells

1986 • 206 citations

Oncogenes and growth control

1985 • 180 citations

Mouse embryonic transforming growth factors related to those isolated from tumor cells.

1982 • 151 citations

Type 1 transforming growth factor beta: amplified expression and secretion of mature and precursor polypeptides in Chinese hamster ovary cells.

1987 • 147 citations

Amino acid sequence of the BSC-1 cell growth inhibitor (polyergin) deduced from the nucleotide sequence of the cDNA.

1988 • 134 citations

Density-dependent regulation of growth of BSC-1 cells in cell culture: growth inhibitors formed by the cells.

1978 • 111 citations

Müllerian inhibiting substance blocks autophosphorylation of the EGF receptor by inhibiting tyrosine kinase

1987 • 62 citations