Mapping of Pax-2 Transcription Activation Domains

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Mouse Small eye results from mutations in a paired-like homeobox-containing gene

1991 • 1,124 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Pax-2 controls multiple steps of urogenital development

1995 • 865 citations

Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region

1991 • 850 citations

PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects

1994 • 683 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3

1991 • 664 citations

Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene

1992 • 643 citations

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.

1992 • 536 citations

Repression of the Insulin-Like Growth Factor II Gene by the Wilms Tumor Suppressor WT1

1992 • 535 citations

Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila

1986 • 497 citations

Pax: A murine multigene family of paired box-containing genes

1991 • 427 citations

Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumor.

1992 • 417 citations

DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.

1993 • 391 citations

Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes.

1994 • 364 citations

undulated, a mutation affecting the development of the mouse skeleton, has a point mutation in the paired box of Pax 1

1988 • 323 citations

Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters.

1992 • 298 citations

DNA-Binding and Transactivation Properties of Pax-6: Three Amino Acids in the Paired Domain Are Responsible for the Different Sequence Recognition of Pax-6 and BSAP (Pax-5)

1995 • 297 citations

Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities

1993 • 284 citations

Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development

1993 • 273 citations

Loss of p53 function through PAX-mediated transcriptional repression.

1995 • 236 citations

Conservation of the paired domain in metazoans and its structure in three isolated human genes.

1989 • 210 citations

Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties.

1993 • 150 citations

Pax-3 contains domains for transcription activation and transcription inhibition.

1994 • 132 citations

Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene

1996 • 125 citations

Molecular basis of splotch and Waardenburg Pax-3 mutations.

1994 • 114 citations

Identification of Novel Pax-2 Binding Sites by Chromatin Precipitation

1996 • 62 citations

Murine Pax-2 Protein Is a Sequence-SpecificTrans-Activator with Expression in the Genital System

1993 • 58 citations

Binding and activation of the promoter for the neural cell adhesion molecule by Pax-8.

1994 • 43 citations