Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Basic Methods in Molecular Biology

1986 • 3,284 citations

Separation of Large DNA Molecules by Contour-Clamped Homogeneous Electric Fields

1986 • 1,525 citations

A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes

1984 • 1,066 citations

The structure and function of the homeodomain

1989 • 1,007 citations

Homeo Boxes in the Study of Development

1987 • 905 citations

Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of Drosophila.

1984 • 776 citations

Chromosomal Imbalance in the Aniridia-Wilms' Tumor Association: 11p Interstitial Deletion

1978 • 726 citations

The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

1988 • 670 citations

The gradient morphogen bicoid is a concentration-dependent transcriptional activator

1989 • 655 citations

Association of Wilms's Tumor with Aniridia, Hemihypertrophy and Other Congenital Malformations

1964 • 603 citations

Murine Developmental Control Genes

1990 • 594 citations

Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system

1990 • 562 citations

Downstream secondary structure facilitates recognition of initiator codons by eukaryotic ribosomes.

1990 • 550 citations

Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene network

1986 • 496 citations

Isolation and nucleotide sequence of the gene encoding human rhodopsin.

1984 • 495 citations

Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland

1990 • 479 citations

The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: Comparison with prokaryotic repressors

1989 • 468 citations

Introduction of a Normal Human Chromosome 11 into a Wilms' Tumor Cell Line Controls Its Tumorigenic Expression

1987 • 407 citations

Aniridia. A review

1984 • 406 citations

Aniridia-Wilms’ tumor association: evidence for specific deletion of 11p13

1979 • 404 citations

Use of restriction enzymes to detect potential gene sequences in mammalian DNA

1987 • 387 citations

The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system

1990 • 383 citations

Isolation, structure, and expression of even-skipped: A second pair-rule gene of Drosophila containing a homeo box

1986 • 380 citations

What determines the specificity of action of Drosophila homeodomain proteins?

1990 • 357 citations

The paired box encodes a second DNA-binding domain in the paired homeo domain protein.

1991 • 349 citations

Small eyes (Sey) : a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse

1986 • 344 citations

Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development

1988 • 304 citations

A molecular analysis of mouse development from 8 to 10 dayspost coitumdetects changes only in embryonic globin expression

1987 • 298 citations

Complete physical map of the WAGR region of 11p13 localizes a candidate Wilms' tumor gene

1990 • 264 citations

HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24.

1991 • 252 citations

The Msh-like homeobox genes define domains in the developing vertebrate eye

1991 • 217 citations

Structure of two genes at the gooseberry locus related to the paired gene and their spatial expression during Drosophila embryogenesis.

1987 • 213 citations

Conservation of the paired domain in metazoans and its structure in three isolated human genes.

1989 • 210 citations

Construction of a General Human Chromosome Jumping Library, with Application to Cystic Fibrosis

1987 • 195 citations

Small eye (Sey): a mouse model for the genetic analysis of craniofacial abnormalities

1988 • 182 citations

Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis

1986 • 171 citations

Secondary structure determination for the Antennapedia homeodomain by nuclear magnetic resonance and evidence for a helix-turn-helix motif.

1988 • 151 citations

A Mouse Model of the Aniridia-Wilms Tumor Deletion Syndrome

1990 • 136 citations

Propagation of some human DNA sequences in bacteriophage lambda vectors requires mutant Escherichia coli hosts.

1985 • 122 citations

Molecular analysis of chromosome 11 deletions in aniridia-Wilms tumor syndrome.

1985 • 122 citations

The β-subunit of follicle-stimulating hormone is deleted in patients with aniridia and Wilms' tumour, allowing a further definition of the WAGR locus

1986 • 118 citations

Gradient fields and homeobox genes

1991 • 117 citations

[65] Cosmid vectors for genomic walking and rapid restriction mapping

1987 • 99 citations

Report of the committee on the genetic constitution of chromosome 11

1990 • 98 citations

Wilms' Tumor and Congenital Aniridia

1968 • 98 citations

Pathology of the Eye

1986 • 95 citations

A systematic approach for detecting high-frequency restriction fragment length polymorphisms using large genomic probes.

1985 • 93 citations

Long range physical map of the Wilms' tumor-aniridia region on human chromosome 11

1988 • 91 citations

The gooseberry-zipper region of Drosophila : five genes encode different spatially restricted transcripts in the embryo

1987 • 87 citations

Familial aniridia and translocation t(4;11)(q22;p13) without Wilms' tumor

1983 • 81 citations

Development of Dickie's small eye, a mutation in the house mouse

1979 • 78 citations

Two Anonymous DNA Segments Distinguish the Wilms' Tumor and Aniridia Loci

1988 • 59 citations

A physical map around the WAGR complex on the short arm of chromosome 11

1989 • 55 citations

Familial isolated aniridia associated with a translocation involving chromosomes 11 and 22 [t(11;22)(p13;q12.2)]

1986 • 53 citations

Cloning of Breakpoints of a Chromosome Translocation Identifies the AN2 Locus

1989 • 53 citations

Location of the gene involving the Small eye mutation on mouse chromosome 2 suggests homology with human aniridia 2 (AN2)

1990 • 47 citations

A probable case of the homozygous condition of the aniridia gene.

1980 • 47 citations

Regional mapping of the gene for human lysosomal acid phosphatase (ACP2) using a hybrid clone panel containing segments of human chromosome 11

1978 • 47 citations

Report of the committee on the genetic constitution of chromosome 11

1989 • 45 citations

Autosomal dominant aniridia: probable linkage to acid phosphatase-1 locus on chromosome 2.

1980 • 45 citations

Cell to Cell Signals in Mammalian Development

1989 • 40 citations

Charon BS (+) and (−), versatile λ phage vectors for constructing directional cDNA libraries and their efficient transfer to plasmids

1988 • 34 citations

Autosomal dominant aniridia linked to the chromosome 11p13 markers catalase and D11S151 in a large Dutch family

1989 • 31 citations

Male pseudohermaphroditism: Genetics and Clinical delineation

1978 • 29 citations

Molecular analysis of gene deletion in aniridia-Wilms tumor association

1985 • 28 citations

A simplified, orientation-specific cDNA cloning strategy

1987 • 25 citations

Long-range restriction map around 11p13 aniridia locus

1989 • 22 citations

HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24

1992 • 15 citations

Wilms' tumor and congenital aniridia

1968 • 10 citations