Phosphatidylinositol 4-Kinase IIIβ Regulates the Transport of Ceramide between the Endoplasmic Reticulum and Golgi

A monomeric red fluorescent protein

2002 • 2,344 citations

A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling

2006 • 1,119 citations

Molecular machinery for non-vesicular trafficking of ceramide

2003 • 994 citations

Visualization of Phosphoinositides That Bind Pleckstrin Homology Domains: Calcium- and Agonist-induced Dynamic Changes and Relationship to Myo-[3H]inositol-labeled Phosphoinositide Pools

1998 • 820 citations

Membrane microdomains and caveolae

1999 • 580 citations

Phosphatidylinositol 4 Phosphate Regulates Targeting of Clathrin Adaptor AP-1 Complexes to the Golgi

2003 • 533 citations

FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P

2004 • 518 citations

ARF mediates recruitment of PtdIns-4-OH kinase-β and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex

1999 • 513 citations

Targeting of Golgi-Specific Pleckstrin Homology Domains Involves Both PtdIns 4-Kinase-Dependent and -Independent Components

2002 • 483 citations

Structural mechanism for sterol sensing and transport by OSBP-related proteins

2005 • 413 citations

The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex.

1989 • 381 citations

Rafts: Scale‐Dependent, Active Lipid Organization at the Cell Surface

2004 • 375 citations

Phosphatidylinositol 4-kinases: old enzymes with emerging functions

2006 • 355 citations

Distinct Roles for the Yeast Phosphatidylinositol 4-Kinases, Stt4p and Pik1p, in Secretion, Cell Growth, and Organelle Membrane Dynamics

2000 • 352 citations

A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids.

1995 • 349 citations

The yeast phosphatidylinositol-4-OH kinase Pik1 regulates secretion at the Golgi

1999 • 311 citations

Direct Involvement of Phosphatidylinositol 4-Phosphate in Secretion in the Yeast Saccharomyces cerevisiae

1999 • 285 citations

Stt4 PI 4-Kinase Localizes to the Plasma Membrane and Functions in the Pkc1-Mediated MAP Kinase Cascade

2002 • 260 citations

Molecular trapping of a fluorescent ceramide analogue at the Golgi apparatus of fixed cells: interaction with endogenous lipids provides a trans-Golgi marker for both light and electron microscopy.

1989 • 258 citations

A Plasma Membrane Pool of Phosphatidylinositol 4-Phosphate Is Generated by Phosphatidylinositol 4-Kinase Type-III Alpha: Studies with the PH Domains of the Oxysterol Binding Protein and FAPP1

2005 • 252 citations

Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein–related proteins and phosphoinositides

2006 • 250 citations

Oxysterol-binding Protein and Vesicle-associated Membrane Protein–associated Protein Are Required for Sterol-dependent Activation of the Ceramide Transport Protein

2006 • 228 citations

Phosphatidylinositol 4-Kinase: Gene Structure and Requirement for Yeast Cell Viability

1993 • 211 citations

Integral membrane lipid phosphatases/phosphotransferases: common structure and diverse functions

2005 • 200 citations

Sphingolipid metabolism in cultured fibroblasts: microscopic and biochemical studies employing a fluorescent ceramide analogue.

1983 • 194 citations

Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion.

1996 • 177 citations

Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion.

1996 • 163 citations

A Novel Family of Phosphatidylinositol 4-Kinases Conserved from Yeast to Humans

2001 • 161 citations

The Phosphatidylinositol 4,5-Biphosphate and TORC2 Binding Proteins Slm1 and Slm2 Function in Sphingolipid Regulation

2006 • 136 citations

Distinct Golgi Populations of Phosphatidylinositol 4-Phosphate Regulated by Phosphatidylinositol 4-Kinases

2005 • 134 citations

A procedure for fractionation of sphingolipid classes by solid-phase extraction on aminopropyl cartridges

2000 • 130 citations

Bridging gaps in phospholipid transport

2005 • 127 citations

Type II Phosphatidylinositol 4-Kinase β Is a Cytosolic and Peripheral Membrane Protein That Is Recruited to the Plasma Membrane and Activated by Rac-GTP

2002 • 125 citations

A Genetic Screen for Aminophospholipid Transport Mutants Identifies the Phosphatidylinositol 4-Kinase, Stt4p, as an Essential Component in Phosphatidylserine Metabolism

1998 • 110 citations

Molecular mechanisms and regulation of ceramide transport

2005 • 103 citations

Cloning of a Human Type II Phosphatidylinositol 4-Kinase Reveals a Novel Lipid Kinase Family

2001 • 95 citations

The Saccharomyces cerevisiae LSB6 Gene Encodes Phosphatidylinositol 4-Kinase Activity

2002 • 89 citations

Discovery of the molecular machinery CERT for endoplasmic reticulum-to-Golgi trafficking of ceramide

2006 • 82 citations

Nonclassical PITPs Activate PLD via the Stt4p PtdIns‐4‐kinase and Modulate Function of Late Stages of Exocytosis in Vegetative Yeast

2005 • 68 citations

Metabolism of short-chain ceramide and dihydroceramide analogues in Chinese hamster ovary (CHO) cells

1995 • 43 citations