Metabolism of short-chain ceramide and dihydroceramide analogues in Chinese hamster ovary (CHO) cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Quantitative analysis of phospholipids by thin‐layer chromatography and phosphorus analysis of spots

1966 • 1,582 citations

Biochemistry of Lipids, Lipoproteins and Membranes

2021 • 1,420 citations

The sphingomyelin cycle and the second messenger function of ceramide.

1994 • 1,255 citations

Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.

1986 • 999 citations

Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.

1990 • 476 citations

An update of the enzymology and regulation of sphingomyelin metabolism

1990 • 460 citations

Biochemistry of Lipids, Lipoproteins and Membranes

1992 • 438 citations

Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus.

1990 • 369 citations

Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N-acyltransferase in mouse liver.

1992 • 343 citations

Ganglioside metabolism. Enzymology, Topology, and regulation.

1993 • 310 citations

Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide.

1993 • 305 citations

Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the Golgi apparatus en route to the plasma membrane.

1985 • 297 citations

Sphingolipid breakdown products: anti-proliferative and tumor-suppressor lipids

1993 • 281 citations

Sphingomyelin and derivatives as cellular signals

1991 • 275 citations

Phosphatidylcholine Metabolism

2020 • 210 citations

Characteristics and partial purification of a novel cytosolic, magnesium-independent, neutral sphingomyelinase activated in the early signal transduction of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.

1994 • 198 citations

Chemistry and Metabolism of Sphingolipids. 3-Oxo Derivatives of N-Acetylsphingosine and N-Acetyldihydrosphingosine

1966 • 185 citations

Enzymology of long-chain base synthesis by liver: Characterization of serine palmitoyltransferase in rat liver microsomes

1984 • 182 citations

Sphingosine-1-phosphate, a metabolite of sphingosine, increases phosphatidic acid levels by phospholipase D activation

1992 • 154 citations

Biosynthesis of sphingolipids: Dihydroceramide and not sphinganine is desaturated by cultured cells

1992 • 144 citations

Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action

1991 • 134 citations

A series of fluorescent N-acylsphingosines: synthesis, physical properties, and studies in cultured cells

1988 • 124 citations

Ceramide-mediated biology. Determination of structural and stereospecific requirements through the use of N-acyl-phenylaminoalcohol analogs.

1992 • 121 citations

The rate of bulk flow from the Golgi to the plasma membrane

1990 • 91 citations

Enzymatic quantification of sphingosine in the picomole range in cultured cells

1989 • 79 citations

Sphingolipid biosynthesis in cultured neurons

1991 • 77 citations

Acetonitrile-hydrochloric acid hydrolysis of gangliosides for high performance liquid chromatographic analysis of their long chain bases.

1983 • 62 citations

Stereospecificities in the Metabolic Reactions of the four Isomeric Sphinganines (Dihydrosphingosines) in Rat Liver

1973 • 61 citations

Elevated ceramide levels in GH4C1 cells treated with retinoic acid

1992 • 57 citations

Specific tritium labeling of cerebrosides at the 3-positions of erythro-sphingosine and threo-sphingosine

1975 • 40 citations

In vivo metabolism of ceramides in rat brain. Fatty acid replacement and esterification of ceramide.

1977 • 37 citations

[52] Use of N-([1-14C]Hexanoyl)-D-erythro-sphingolipids to assay sphingolipid metabolism

1992 • 31 citations

In,vivo conversion of erythro and threo DL-sphingosine-3H to ceramide and sphingomyelin

1966 • 23 citations

Utilization of exogenously supplied sphingosine analogues for sphingolipid biosynthesis in Chinese hamster ovary and mouse LM cell fibroblasts.

1993 • 14 citations

Enhanced N-acylation of palmitic acid in sphingomyelin of antibody-stimulated L cells

1984 • 11 citations