Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion.

Mechanisms of intracellular protein transport

1994 • 2,280 citations

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

1994 • 749 citations

Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics.

1994 • 533 citations

Multiple calcium-dependent processes related to secretion in bovine chromaffin cells

1993 • 524 citations

ATP-dependent inositide phosphorylation required for Ca2+-activated secretion

1995 • 508 citations

Calcium-dependence of catecholamine release from bovine adrenal medullary cells after exposure to intense electric fields

1982 • 500 citations

A Specific and Sensitive Assay for Disulfides

1968 • 446 citations

Phosphatidylinositol transfer protein required for ATP-dependent priming of Ca2+-activated secretion

1993 • 346 citations

Resolution of regulated secretion into sequential MgATP-dependent and calcium-dependent stages mediated by distinct cytosolic proteins.

1992 • 286 citations

Novel function of phosphatidylinositol 4,5-bisphosphate as a cofactor for brain membrane phospholipase D.

1994 • 277 citations

Releasable pools and the kinetics of exocytosis in adrenal chromaffin cells

1994 • 254 citations

Tyrosine phosphorylation in T cells is regulated by phosphatase activity: studies with phenylarsine oxide.

1990 • 246 citations

Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.

1994 • 245 citations

Evidence that the inositol phospholipids are necessary for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP

1990 • 227 citations

MgATP-independent and MgATP-dependent Exocytosis

1989 • 209 citations

Kinetic analysis of secretion from permeabilized adrenal chromaffin cells reveals distinct components.

1992 • 208 citations

Requirement for Phosphatidylinositol Transfer Protein in Epidermal Growth Factor Signaling

1995 • 180 citations

Regulated exocytosis

1993 • 179 citations

Phosphatidylinositol-3-kinase in isolated rat adipocytes. Activation by insulin and subcellular distribution.

1992 • 137 citations

Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate.

1991 • 123 citations

A major role for protein kinase C in calcium‐activated exocytosis in permeabilised adrenal chromaffin cells

1988 • 97 citations

Phosphatidylinositol kinase. A component of the chromaffin-granule membrane

1973 • 91 citations

Mechanism of vanadate-induced activation of tyrosine phosphorylation and of the respiratory burst in HL60 cells. Role of reduced oxygen metabolites

1991 • 90 citations

In chromaffin cells, the mammalian Sec1p homologue is a syntaxin 1A-binding protein associated with chromaffin granules.

1994 • 86 citations

Phosphatidylinositol 4-kinase is a component of glucose transporter (GLUT 4)-containing vesicles

1991 • 83 citations

Phosphotyrosyl turnover in insulin signaling. Characterization of two membrane-bound pp15 protein tyrosine phosphatases from 3T3-L1 adipocytes.

1991 • 79 citations

Insulin-stimulated Protein Tyrosine Phosphorylation in Intact Cells Evaluated by Giant Two-dimensional Gel Electrophoresis

1989 • 66 citations

Platelet-derived growth factor activates membrane-associated phosphatidylinositol 3-kinase and mediates its translocation from the cytosol. Detection of enzyme activity in detergent-solubilized cell extracts

1992 • 64 citations

Catecholamine secretion from digitonin-treated PC12 cells. Effects of Ca2+, ATP, and protein kinase C activators.

1986 • 61 citations

Catalytic properties of a purified phosphatidylinositol-4-phosphate kinase from rat brain

1986 • 59 citations

Screening of phosphatidylinositol kinase inhibitors from Streptomyces.

1989 • 58 citations

A monoclonal antibody distinguishes two types of phosphatidylinositol 4-kinase

1991 • 56 citations

Digitonin‐Permeabilized Cells Are Exocytosis Competent

1987 • 55 citations

Novel inositol containing phospholipids and phosphates: their synthesis and possible new roles in cellular signalling

1993 • 43 citations

Phosphatidylinositol kinase of bovine adrenal chromaffin granules: Kinetic properties and inhibition by low concentrations of Ca2+

1988 • 34 citations

Identification of an actively phosphorylated component of adrenal medulla chromaffin granules

1971 • 30 citations

Lack of Phospholipase D Activity in Chromaffin Cells: Bradykinin‐Stimulated Phosphatidic Acid Formation Involves Phospholipase C in Chromaffin Cells but Phospholipase D in PC12 Cells

1991 • 29 citations

Effects of Arsenicals on the Secretory Process in Chromaffin Cells

1994 • 11 citations

Purification and characterization of corticosteroid side chain isomerase

1990 • 11 citations

Deleted Work

1955 • 0 citations