Bio-specific sequences and domains in heparan sulphate and the regulation of cell growth and adhesion

Proteoglycans: Structures And Interactions

1991 • 1,596 citations

Biology of the Syndecans: A Family of Transmembrane Heparan Sulfate Proteoglycans

1992 • 1,095 citations

Heparin Structure and Interactions with Basic Fibroblast Growth Factor

1996 • 789 citations

Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4.

1993 • 542 citations

Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate.

1992 • 511 citations

Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor.

1993 • 449 citations

Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate Proteoglycan

1993 • 420 citations

An unusual feature revealed by the crystal structure at 2.2 Å resolution of human transforming growth fact or-β2

1992 • 337 citations

Interaction of hepatocyte growth factor with heparan sulfate. Elucidation of the major heparan sulfate structural determinants

1994 • 316 citations

Energetic Characterization of the Basic Fibroblast Growth Factor-Heparin Interaction: Identification of the Heparin Binding Domain

1994 • 296 citations

Domain Structure of Heparan Sulfates from Bovine Organs

1996 • 281 citations

Heparan Sulfate Oligosaccharides Require 6-O-Sulfation for Promotion of Basic Fibroblast Growth Factor Mitogenic Activity

1998 • 276 citations

The Interaction of the Transforming Growth Factor-βs with Heparin/Heparan Sulfate Is Isoform-specific

1997 • 247 citations

Kinetics of basic fibroblast growth factor binding to its receptor and heparan sulfate proteoglycan: a mechanism for cooperativity

1992 • 236 citations

Liver heparan sulfate structure. A novel molecular design

1994 • 235 citations

Differences in the Interaction of Heparin with Arginine and Lysine and the Importance of these Basic Amino Acids in the Binding of Heparin to Acidic Fibroblast Growth Factor

1995 • 219 citations

Crystal structure of the tenth type III cell adhesion module of human fibronectin

1994 • 207 citations

Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor.

1994 • 202 citations

A synthetic peptide from the COOH-terminal heparin-binding domain of fibronectin promotes focal adhesion formation.

1993 • 202 citations

Transforming growth factor‐β1 is a heparin‐binding protein: Identification of putative heparin‐binding regions and isolation of heparins with varying affinity for TGF‐β1

1992 • 188 citations

Structural Modification of Fibroblast Growth Factor-binding Heparan Sulfate at a Determinative Stage of Neural Development

1998 • 183 citations

Sulfated Oligosaccharides Promote Hepatocyte Growth Factor Association and Govern Its Mitogenic Activity

1995 • 170 citations

Hepatocyte Growth Factor/Scatter Factor Binds with High Affinity to Dermatan Sulfate

1998 • 150 citations

Localization of the major heparin-binding site in fibronectin.

1991 • 149 citations

Presence of N-Unsubstituted Glucosamine Units in Native Heparan Sulfate Revealed by a Monoclonal Antibody

1995 • 147 citations

Identification and concerted function of two receptor binding surfaces on basic fibroblast growth factor required for mitogenesis.

1994 • 139 citations

Patterns of sulphation in heparan sulphate: Polymorphism based on a common structural theme

1992 • 133 citations

Interaction of Heparan Sulfate from Mammary Cells with Acidic Fibroblast Growth Factor (FGF) and Basic FGF

1998 • 130 citations

Heparin Binding and Oligomerization of Hepatocyte Growth Factor/Scatter Factor Isoforms

1997 • 126 citations

Hairpin loop and second kringle domain are essential sites for heparin binding and biological activity of hepatocyte growth factor.

1994 • 107 citations

Divalent Cations and Heparin/Heparan Sulfate Cooperate to Control Assembly and Activity of the Fibroblast Growth Factor Receptor Complex

1996 • 103 citations

Heparin Binding by Fibronectin Module III-13 Involves Six Discontinuous Basic Residues Brought Together to Form a Cationic Cradle

1995 • 103 citations

Structural requirements in heparin for binding and activation of FGF-1 and FGF-4 are different from that for FGF-2

1994 • 100 citations

Heparin-induced Self-association of Fibroblast Growth Factor-2

1997 • 99 citations

Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo

1998 • 97 citations

Interaction of heparin with fibronectin and isolated fibronectin domains

1990 • 95 citations

Properly Oriented Heparin−Decasaccharide-Induced Dimers Are the Biologically Active Form of Basic Fibroblast Growth Factor^,

1997 • 95 citations

Thrombin inactivates acidic fibroblast growth factor but not basic fibroblast growth factor

1988 • 77 citations

Structure and Function of Heparin and Heparan Sulfate; Heparinoid Library and Modification of FGF-Activities.

1998 • 64 citations

Structural domains of heparan sulphate for specific recognition of the C-terminal heparin-binding domain of human plasma fibronectin (HEPII)

1996 • 64 citations

The solution structure of the N-terminal domain of hepatocyte growth factor reveals a potential heparin-binding site

1998 • 60 citations

Reductive methylation of lysine residues in acidic fibroblast growth factor: effect on mitogenic activity and heparin affinity

1988 • 60 citations

Transforming growth factor .beta.1: Secondary structure as determined by heteronuclear magnetic resonance spectroscopy

1993 • 59 citations

Hepatocyte Growth Factor/Scatter Factor Has Distinct Classes of Binding Site in Heparan Sulfate from Mammary Cells

1998 • 54 citations

Binding of heparin by type III domains and peptides from the carboxy terminal Hep-2 region of fibronectin

1993 • 49 citations

Sequence analysis of heparan sulphate indicates defined location of N-sulphated glucosamine and iduronate 2-sulphate residues proximal to the protein-linkage region

1991 • 48 citations

Glycosaminoglycans Can Influence Fibroblast Growth Factor-2 Mitogenicity without Significant Growth Factor Binding

1997 • 47 citations

Identification of an extended N-acetylated sequence adjacent to the protein-linkage region of fibroblast heparan sulphate

1987 • 46 citations

The Interaction and Regulation of Basic and Acidic Fibroblast Growth Factors by Heparan Sulphate.

1998 • 18 citations