Epitope mapping of factor VIII inhibitor antibodies of Chinese origin

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

Molecular cloning of a cDNA encoding human antihaemophilic factor

1984 • 937 citations

A Survey of 215 Non-Hemophilic Patients with Inhibitors to Factor VIII

1981 • 773 citations

A More Uniform Measurement of Factor VIII Inhibitors

1975 • 498 citations

Haemophilia A: Mutation Type Determines Risk of Inhibitor Formation

1995 • 336 citations

A More Uniform Measurement of Factor VIII Inhibitors

1975 • 316 citations

A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity.

1986 • 314 citations

9 Acquired inhibitors

1996 • 186 citations

The Inhibitor Antibody Response Is More Complex in Hemophilia A Patients Than in Most Nonhemophiliacs With Factor VIII Autoantibodies

1997 • 180 citations

FVIII inhibitor IgG subclass and FVIII polypeptide specificity determined by immunoblotting

1987 • 158 citations

Anti-factor VIII antibodies of hemophiliac patients are frequently directed towards nonfunctional determinants and do not exhibit isotypic restriction

1993 • 155 citations

Localization of epitopes for human factor VIII inhibitor antibodies by immunoblotting and antibody neutralization

1989 • 130 citations

The Role of Genetics in Inhibitor Formation

1999 • 83 citations

Expression and characterization of human factor IX and factor IX-factor X chimeras in mouse C127 cells.

1990 • 67 citations

Inhibition of human coagulation factor VIII by monoclonal antibodies. Mapping of functional epitopes with the use of recombinant factor VIII fragments

1989 • 65 citations

CD4+ T Cell Response to Factor VIII in Hemophilia A, Acquired Hemophilia, and Healthy Subjects

1999 • 65 citations

Immunoblot analysis shows changes in factor VIII inhibitor chain specificity in factor VIII inhibitor patients over time

1988 • 47 citations

Characterization of genetic defects of hemophilia A in patients of Chinese origin.

1993 • 36 citations

Mapping of the minimal domain encoding a conformational epitope by λ phage surface display: factor VIII inhibitor antibodies from haemophilia A patients

1999 • 32 citations

Characterization of genetic defects of hemophilia a in patients of chinese origin

1993 • 31 citations

Identification of a F.VIII epitope recognized by a human hemophilic inhibitor

1989 • 31 citations

Localization of a factor VIII-inhibiting antibody epitope to a region between residues 338 and 362 of factor VIII heavy chain.

1988 • 23 citations

Characterization of Factor VIII B-Cell Inhibitory Epitopes

1999 • 19 citations

Identification of Novel Factor VIII Inhibitor Epitopes using Synthetic Peptide Arrays

1997 • 15 citations

Characterization of a factor VIII immunogenic site using factor VIII synthetic peptide 1687–1695 and rabbit anti-peptide antibodies

1992 • 13 citations

Genetic diagnosis of haemophilia A of Chinese origin

1995 • 12 citations

Identification of plasma antibody epitopes and gene abnormalities in Japanese hemophilia A patients with factor VIII inhibitor.

2000 • 6 citations