Neuregulin in Cardiac Hypertrophy in Rats With Aortic Stenosis

Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts.

1998 • 1,013 citations

Identification of Heregulin, a Specific Activator of p185 ^erbB2

1992 • 963 citations

Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response

1991 • 798 citations

Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors.

1989 • 742 citations

Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family.

1993 • 724 citations

The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand‐receptor interactions

1997 • 719 citations

Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy

1990 • 641 citations

Neuregulins Promote Survival and Growth of Cardiac Myocytes

1998 • 493 citations

Neuregulins and Their Receptors: A Versatile Signaling Module in Organogenesis and Oncogenesis

1997 • 471 citations

Angiotensin II Induces Apoptosis of Adult Ventricular MyocytesIn Vitro

1997 • 413 citations

Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases

1997 • 390 citations

Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4

1997 • 385 citations

Isoform-specific expression and function of neuregulin

1997 • 384 citations

GGF/Neuregulin Is a Neuronal Signal That Promotes the Proliferation and Survival and Inhibits the Differentiation of Oligodendrocyte Progenitors

1996 • 374 citations

Death by Design

1997 • 364 citations

Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding.

1993 • 359 citations

Axonal Interactions Regulate Schwann Cell Apoptosis in Developing Peripheral Nerve: Neuregulin Receptors and the Role of Neuregulins

1996 • 321 citations

Serial Echocardiographic-Doppler Assessment of Left Ventricular Geometry and Function in Rats With Pressure-Overload Hypertrophy

1995 • 306 citations

Schwann cell apoptosis at developing neuromuscular junctions is regulated by glial growth factor

1996 • 283 citations

The influence of heregulins on human Schwann cell proliferation

1995 • 252 citations

Angiotensin-converting enzyme inhibition prolongs survival and modifies the transition to heart failure in rats with pressure overload hypertrophy due to ascending aortic stenosis.

1994 • 240 citations

Neuregulins in Development

1996 • 229 citations

Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development.

1996 • 228 citations

Distribution and functional significance of cardiac angiotensin converting enzyme in hypertrophied rat hearts.

1993 • 191 citations

Neuregulins and their receptors

1995 • 178 citations

The neuregulin, glial growth factor 2, diminishes autoimmune demyelination and enhances remyelination in a chronic relapsing model for multiple sclerosis

1998 • 152 citations

Brain neurons and glial cells express Neu differentiation factor/heregulin: a survival factor for astrocytes.

1994 • 147 citations

Cardiac myocytes as targets for the action of peptide growth factors.

1990 • 126 citations

Treatment With Growth Hormone Enhances Contractile Reserve and Intracellular Calcium Transients in Myocytes From Rats With Postinfarction Heart Failure

1999 • 118 citations

Angiotensin AT ₁ Receptor Inhibition

1997 • 94 citations

Endothelin and angiotensin II stimulation of Na+-H+ exchange is impaired in cardiac hypertrophy.

1997 • 92 citations

Conversion of a radioresistant phenotype to a more sensitive one by disabling erbB receptor signaling in human cancer cells

1998 • 77 citations

Neuregulin Expression in PNS Neurons: Isoforms and Regulation by Target Interactions

1997 • 68 citations

Alteration of growth responses in established cardiac pressure overload hypertrophy in rats with aortic banding.

1995 • 63 citations

Long-term Angiotensin-Converting Enzyme Inhibition With Fosinopril Improves Depressed Responsiveness to Ca ²⁺ in Myocytes From Aortic-Banded Rats

1996 • 47 citations

Neuregulins as potential drugs for neurological disorders.

1996 • 22 citations

Neuregulins as Potential Neuroprotective Agents

1997 • 13 citations

Quantitative Analysis of Her-2/neu (ERBB2) Gene Expression Using Reverse Transcriptase Polymerase Chain Reaction

1993 • 9 citations

Quantitative Analysis of Her-2/neu (ERBB2) Gene Expression Using Reverse Transcriptase Polymerase Chain Reaction

1993 • 4 citations

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