Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATα2 repressor

Methods in yeast genetics

1979 • 7,824 citations

Current protocols in molecular biology

1988 • 7,584 citations

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

Methods in Yeast Genetics

1988 • 4,905 citations

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

A Multiubiquitin Chain Is Confined to Specific Lysine in a Targeted Short-Lived Protein

1989 • 1,463 citations

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

1992 • 1,402 citations

The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses

1987 • 850 citations

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

1993 • 786 citations

The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis

1989 • 711 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

A regulatory hierarchy for cell specialization in yeast

1989 • 612 citations

THE UBIQUITIN-CONJUGATION SYSTEM

1992 • 561 citations

Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.

1990 • 520 citations

The N-end rule

1992 • 464 citations

Regulation by proteolysis: energy-dependent proteases and their targets

1992 • 458 citations

The Yeast Cell Cycle Gene CDC34 Encodes a Ubiquitin-Conjugating Enzyme

1988 • 435 citations

Ubiquitination

1991 • 430 citations

Targeting of E. coli β-galactosidase to the nucleus in yeast

1984 • 386 citations

Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization

1991 • 312 citations

Functional heterogeneity of ubiquitin carrier proteins.

1985 • 281 citations

The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme.

1991 • 268 citations

Ubiquitin as a degradation signal.

1992 • 261 citations

Resistance to cadmium mediated by ubiquitin-dependent proteolysis

1993 • 261 citations

In vivo degradation of a transcriptional regulator: The yeast α2 repressor

1990 • 243 citations

The short-lived MAT alpha 2 transcriptional regulator is ubiquitinated in vivo.

1991 • 242 citations

Epitope-tagged ubiquitin. A new probe for analyzing ubiquitin function.

1991 • 212 citations

The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymes

1992 • 202 citations

Structure of a diubiquitin conjugate and a model for interaction with ubiquitin conjugating enzyme (E2).

1992 • 191 citations

Structure of a diubiquitin conjugate and a model for interaction with ubiquitin conjugating enzyme (E2).

1992 • 175 citations

In vitro mutation analysis of the mating-type locus in yeast

1981 • 170 citations

Yeast genes fused to beta-galactosidase in Escherichia coli can be expressed normally in yeast.

1981 • 165 citations

UBC1 encodes a novel member of an essential subfamily of yeast ubiquitin-conjugating enzymes involved in protein degradation.

1990 • 160 citations

Regulation by proteolysis: energy-dependent proteases and their targets.

1992 • 143 citations

A chimeric ubiquitin conjugating enzyme that combines the cell cycle properties of CDC34 (UBC3) and the DNA repair properties of RAD6 (UBC2): implications for the structure, function and evolution of the E2s.

1992 • 104 citations

Three-dimensional structure of a ubiquitin-conjugating enzyme (E2).

1992 • 94 citations

Ubiquitin and intracellular protein degradation

1992 • 84 citations

Mutations in RAD6, a yeast gene encoding a ubiquitin-conjugating enzyme, stimulate retrotransposition.

1990 • 69 citations

Identification of the DNA sequences controlling the expression of the MAT alpha locus of yeast.

1986 • 59 citations

Mitotic sectored colonies: evidence of heteroduplex DNA formation during direct repeat recombination.

1988 • 52 citations

Cloning and characterization of a Saccharomyces cerevisiae gene encoding a new member of the ubiquitin-conjugating protein family

1991 • 50 citations

A major ubiquitin conjugation system in wheat germ extracts involves a 15-kDa ubiquitin-conjugating enzyme (E2) homologous to the yeast UBC4/UBC5 gene products.

1993 • 42 citations

Purification and characterization of yeast orotidine 5'-monophosphate decarboxylase overexpressed from plasmid PGU2

1991 • 30 citations

[24] Regulated GAL4 expression cassette providing controllable and high-level output from high-copy galactose promoters in yeast

1990 • 29 citations

The structure and function of RAD6 and RAD18 DNA repair genes of Saccharomyces cerevisiae

1989 • 28 citations

QRI8, a novel ubiquitin-conjugating enzyme in Saccharomyces cerevisiae

1992 • 12 citations

Functions of Intracellular Protein Degradation in Yeast

1991 • 7 citations