Platelet-Endothelial Cell Adhesion Molecule-1 (CD31), a Scaffolding Molecule for Selected Catenin Family Members Whose Binding Is Mediated by Different Tyrosine and Serine/Threonine Phosphorylation

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

1999 • 3,566 citations

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

1991 • 2,499 citations

The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway

1999 • 2,206 citations

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

1996 • 1,946 citations

PECAM-1 is required for transendothelial migration of leukocytes.

1993 • 1,134 citations

Target genes of β-catenin–T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

1999 • 807 citations

The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors

1999 • 679 citations

The biology of PECAM-1.

1997 • 669 citations

Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways

1997 • 543 citations

E-cadherin binding prevents β-catenin nuclear localization and β-catenin/LEF-1-mediated transactivation

1999 • 526 citations

Plakoglobin: A protein common to different kinds of intercellular adhering junctions

1986 • 508 citations

Involvement of Platelet-Endothelial Cell Adhesion Molecule-1 in Neutrophil Recruitment in Vivo

1993 • 468 citations

Genetic Evidence for Functional Redundancy of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1): CD31-Deficient Mice Reveal PECAM-1-Dependent and PECAM-1-Independent Functions

1999 • 430 citations

Desmosomes and hemidesmosomes: structure and function of molecular components

1996 • 350 citations

Differential molecular interactions of β-catenin and plakoglobin in adhesion, signaling and cancer

1998 • 343 citations

Tyrosine phosphorylation and cadherin/catenin function

1997 • 318 citations

Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells

1997 • 285 citations

Differential Nuclear Translocation and Transactivation Potential of β-Catenin and Plakoglobin

1998 • 271 citations

Distinct signal transduction pathways are utilized during the tube formation and survival phases of in vitro angiogenesis

1998 • 266 citations

The Amino-terminal Domain of Desmoplakin Binds to Plakoglobin and Clusters Desmosomal Cadherin–Plakoglobin Complexes

1997 • 237 citations

Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly.

1996 • 227 citations

Interendothelial junctions: structure, signalling and functional roles

1997 • 219 citations

The Protein-tyrosine Phosphatase SHP-2 Binds Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) and Forms a Distinct Signaling Complex during Platelet Aggregation

1997 • 215 citations

Endothelial cell tube formation depends on cadherin 5 and CD31 interactions with filamentous actin.

1997 • 209 citations

Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cells.

1994 • 196 citations

Functional analysis of desmoplakin domains: specification of the interaction with keratin versus vimentin intermediate filament networks.

1993 • 178 citations

Regulation of β-Catenin Levels and Localization by Overexpression of Plakoglobin and Inhibition of the Ubiquitin-Proteasome System

1997 • 157 citations

Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cells.

1997 • 155 citations

Two-hybrid Analysis Reveals Fundamental Differences in Direct Interactions between Desmoplakin and Cell Type-specific Intermediate Filaments

1997 • 151 citations

Activation-dependent changes in human platelet PECAM-1: phosphorylation, cytoskeletal association, and surface membrane redistribution.

1992 • 137 citations

A hemangioendothelioma-derived cell line: its use as a model for the study of endothelial cell biology.

1990 • 131 citations

VE-cadherin and desmoplakin are assembled into dermal microvascular endothelial intercellular junctions: A pivotal role for plakoglobin in the recruitment of desmoplakin to intercellular junctions

1998 • 129 citations

Structural and functional aspects of intercellular junctions in vascular endothelium

1998 • 128 citations

Complexus adhaerentes, a new group of desmoplakin-containing junctions in endothelial cells: the syndesmos connecting retothelial cells of lymph nodes.

1993 • 127 citations

PECAM-1 (CD31) functions as a reservoir for and a modulator of tyrosine-phosphorylated β-catenin

1999 • 126 citations

Platelet endothelial cell adhesion molecule, PECAM‐1, modulates cell migration

1992 • 120 citations

Recruitment and Activation of SHP-1 Protein-tyrosine Phosphatase by Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1)

1998 • 116 citations

The Protein-tyrosine Phosphatase SHP-2 Associates with Tyrosine-phosphorylated Adhesion Molecule PECAM-1 (CD31)

1997 • 106 citations

Differential association of cytoplasmic signalling molecules SHP‐1, SHP‐2, SHIP and phospholipase C‐γ1 with PECAM‐1/CD31

1999 • 103 citations

Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule 1.

1996 • 102 citations

Platelet Endothelial Cell Adhesion Molecule-1 Is Phosphorylatable by c-Src, Binds Src-Src homology 2 Domain, and Exhibits Immunoreceptor Tyrosine-based Activation Motif-like Properties

1997 • 99 citations

Functional Association of Platelet Endothelial Cell Adhesion Molecule-1 and Phosphoinositide 3-Kinase in Human Neutrophils

1998 • 81 citations

Desmoplakin expression and organization at human umbilical vein endothelial cell-to-cell junctions

1996 • 76 citations

PDGF induces reorganization of vimentin filaments

1998 • 74 citations

Platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) tyrosine phosphorylation state changes during vasculogenesis in the murine conceptus.

1997 • 66 citations

T cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant β-catenin

1999 • 65 citations

Hyperglycemia-Induced Vasculopathy in the Murine Vitelline Vasculature

1999 • 63 citations

Platelet endothelial cell adhesion molecule-1 expression modulates endothelial cell migration in vitro.

1998 • 58 citations

Cobalt chloride-induced signaling in endothelium leading to the augmented adherence of sickle red blood cells and transendothelial migration of monocyte-like HL-60 cells is blocked by PAF-receptor antagonist

1999 • 39 citations

Functional regulation of platelet/endothelial cell adhesion molecule-1 by TGF-beta 1 in promonocytic U-937 cells.

1994 • 33 citations