Differential association of cytoplasmic signalling molecules SHP‐1, SHP‐2, SHIP and phospholipase C‐γ1 with PECAM‐1/CD31

SH2 domains recognize specific phosphopeptide sequences

1993 • 2,685 citations

The biology of PECAM-1.

1997 • 669 citations

MODULAR PEPTIDE RECOGNITION DOMAINS IN EUKARYOTIC SIGNALING

1997 • 558 citations

Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM).

1995 • 463 citations

The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules

1992 • 438 citations

CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion.

1992 • 383 citations

Switched at birth: a new family for PECAM-1

1999 • 257 citations

Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-$gamma;1 complexed with a high affinity binding peptide

1994 • 239 citations

Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma.

1992 • 231 citations

The Protein-tyrosine Phosphatase SHP-2 Binds Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) and Forms a Distinct Signaling Complex during Platelet Aggregation

1997 • 215 citations

The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp.

1993 • 214 citations

The Inositol 5′-Phosphatase SHIP Binds to Immunoreceptor Signaling Motifs and Responds to High Affinity IgE Receptor Aggregation

1996 • 180 citations

Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cells.

1997 • 155 citations

Characterization of Phosphotyrosine Binding Motifs in the Cytoplasmic Domain of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Are Required for the Cellular Association and Activation of the Protein-tyrosine Phosphatase, SHP-2

1997 • 151 citations

The Negative Signaling Molecule SH2 Domain-containing Inositol-Polyphosphate 5-Phosphatase (SHIP) Binds to the Tyrosine-phosphorylated β Subunit of the High Affinity IgE Receptor

1997 • 143 citations

Integrins and inside-out signal transduction: converging signals from PKC and PIP3

1997 • 139 citations

Activation-dependent changes in human platelet PECAM-1: phosphorylation, cytoskeletal association, and surface membrane redistribution.

1992 • 137 citations

The Src Homology 2 (SH2) Domain of SH2-containing Inositol Phosphatase (SHIP) Is Essential for Tyrosine Phosphorylation of SHIP, Its Association with Shc, and Its Induction of Apoptosis

1997 • 133 citations

Recruitment and Activation of SHP-1 Protein-tyrosine Phosphatase by Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1)

1998 • 116 citations

The Protein-tyrosine Phosphatase SHP-2 Associates with Tyrosine-phosphorylated Adhesion Molecule PECAM-1 (CD31)

1997 • 106 citations

Inhibitory receptors abound?

1997 • 103 citations

Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule 1.

1996 • 102 citations

Regulation of Mouse PECAM-1 Tyrosine Phosphorylation by the Src and Csk Families of Protein-tyrosine Kinases

1998 • 101 citations

Platelet endothelial cell adhesion molecule‐1 is a major SH‐PTP2 binding protein in vascular endothelial cells

1997 • 101 citations

Tyrosine Phosphorylation and Relocation of SHIP Are Integrin-mediated in Thrombin-stimulated Human Blood Platelets

1997 • 99 citations

Platelet Endothelial Cell Adhesion Molecule-1 Is Phosphorylatable by c-Src, Binds Src-Src homology 2 Domain, and Exhibits Immunoreceptor Tyrosine-based Activation Motif-like Properties

1997 • 99 citations

Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain

1994 • 87 citations

Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin release.

1998 • 81 citations

Definition of the Sites of Interaction between the Protein Tyrosine Phosphatase SHP-1 and CD22

1999 • 79 citations

Association of Tyrosine Phosphatases SHP-1 and SHP-2, Inositol 5-Phosphatase SHIP with gp49B1, and Chromosomal Assignment of the Gene

1998 • 78 citations

Ligation of CD31/PECAM-1 modulates the function of lymphocytes, monocytes and neutrophils

1998 • 54 citations

Identification of residues in the beta platelet-derived growth factor receptor that confer specificity for binding to phospholipase C-gamma 1.

1993 • 41 citations

Tyrosine Phosphorylation of Platelet Endothelial Cell Adhesion Molecule-1 Induced by Lysophosphatidylcholine in Cultured Endothelial Cells

1998 • 18 citations

Tyr1009 and Tyr1021 in the platelet-derived growth factor beta-receptor mediate agonist triggered calcium signalling.

1998 • 6 citations