The Amino-terminal Domain of Desmoplakin Binds to Plakoglobin and Clusters Desmosomal Cadherin–Plakoglobin Complexes

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA

1963 • 3,559 citations

Structure and Function of Intercellular Junctions

1974 • 1,339 citations

Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule.

1990 • 753 citations

Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA

1987 • 752 citations

Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex.

1995 • 739 citations

Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin.

1995 • 651 citations

A Homolog of the armadillo Protein in Drosophila (Plakoglobin) Associated with E-Cadherin

1991 • 632 citations

Assembly of the cadherin-catenin complex in vitro with recombinant proteins

1994 • 557 citations

The 102 kd cadherin-associated protein: Similarity to vinculin and posttranscriptional regulation of expression

1991 • 501 citations

The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin

1990 • 474 citations

Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin

1994 • 405 citations

The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties.

1992 • 385 citations

Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex.

1995 • 341 citations

Cadherin dysfunction in a human cancer cell line: possible involvement of loss of alpha-catenin expression in reduced cell-cell adhesiveness.

1992 • 337 citations

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.

1996 • 335 citations

Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules.

1990 • 327 citations

Embryonic Heart and Skin Defects in Mice Lacking Plakoglobin

1996 • 323 citations

Desmosomes and hemidesmosomes

1993 • 310 citations

Nomenclature of the desmosomal cadherins.

1993 • 292 citations

Making a connection: direct binding between keratin intermediate filaments and desmosomal proteins.

1994 • 283 citations

Desmosomes and Hemidesmosomes: Constitutive Molecular Components

1990 • 280 citations

Plakophilins 2a and 2b: constitutive proteins of dual location in the karyoplasm and the desmosomal plaque.

1996 • 278 citations

Structure of the human desmoplakins. Implications for function in the desmosomal plaque.

1990 • 275 citations

Characterization of the interactions of α-catenin with α-actinin and β-catenin/plakoglobin

1997 • 260 citations

Cross-Talk between Adherens Junctions and Desmosomes Depends on Plakoglobin

1997 • 256 citations

Intermediate filaments in disease

1995 • 248 citations

Direct Ca2+-dependent Heterophilic Interaction between Desmosomal Cadherins, Desmoglein and Desmocollin, Contributes to Cell–Cell Adhesion

1997 • 242 citations

Cytoskeleton—membrane interactions

1996 • 231 citations

Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly.

1996 • 227 citations

Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein.

1989 • 223 citations

Isolation of the intercellular glycoproteins of desmosomes.

1981 • 211 citations

[27] Gene identification using the yeast two-hybrid system

1996 • 195 citations

The desmoplakin carboxyl terminus coaligns with and specifically disrupts intermediate filament networks when expressed in cultured cells.

1992 • 194 citations

Cell type-specific desmosomal plaque proteins of the plakoglobin family: plakophilin 1 (band 6 protein)

1995 • 190 citations

Desmosomes and cytoskeletal architecture in epithelial differentiation: cell type-specific plaque components and intermediate filament anchorage.

1994 • 185 citations

Functional analysis of desmoplakin domains: specification of the interaction with keratin versus vimentin intermediate filament networks.

1993 • 178 citations

Contributions of cytoplasmic domains of desmosomal cadherins to desmosome assembly and intermediate filament anchorage

1993 • 178 citations

Single Amino Acid Substitutions in Proteins of the armadillo Gene Family Abolish Their Binding to α-Catenin

1996 • 174 citations

Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin.

1996 • 167 citations

CHEMICAL CHARACTERIZATION OF ISOLATED EPIDERMAL DESMOSOMES

1974 • 158 citations

Two-hybrid Analysis Reveals Fundamental Differences in Direct Interactions between Desmoplakin and Cell Type-specific Intermediate Filaments

1997 • 151 citations

Identification of Plakoglobin Domains Required for Association with N-cadherin and α-Catenin

1995 • 144 citations

Interactions of the cytoplasmic domain of the desmosomal cadherin Dsg1 with plakoglobin.

1994 • 140 citations

Cloning and characterization of a new armadillo family member, p0071, associated with the junctional plaque: evidence for a subfamily of closely related proteins

1996 • 139 citations

Band 6 protein, a major constituent of desmosomes from stratified epithelia, is a novel member of the armadillo multigene family

1994 • 138 citations

Intermediate filaments and disease: mutations that cripple cell strength.

1994 • 132 citations

Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome

1991 • 131 citations

Desmosomal Cadherin Binding Domains of Plakoglobin

1996 • 122 citations

Desmosomal glycoproteins II and III. Cadherin-like junctional molecules generated by alternative splicing

1991 • 120 citations

Roles of plakoglobin end domains in desmosome assembly

1997 • 114 citations

Continual assembly of half-desmosomal structures in the absence of cell contacts and their frustrated endocytosis: a coordinated Sisyphus cycle.

1995 • 109 citations

Desmoplakin I and desmoplakin II

1989 • 105 citations

Extracellular Domain of Pemphigus Vulgaris Antigen (Desmoglein 3) Mediates Weak Homophilic Adhesion

1994 • 103 citations

Posttranslational regulation of plakoglobin expression. Influence of the desmosomal cadherins on plakoglobin metabolic stability.

1994 • 102 citations

Molecular mechanisms of epithelial cell junctions : from development to disease

1994 • 99 citations

Molecular structure of the human desmoplakin I and II amino terminus.

1992 • 96 citations

The binding of plakoglobin to desmosomal cadherins: patterns of binding sites and topogenic potential.

1996 • 96 citations

Characterization of pinin, a novel protein associated with the desmosome-intermediate filament complex.

1996 • 92 citations

Analysis of Desmosomal Cadherin–Adhesive Function and Stoichiometry of Desmosomal Cadherin-Plakoglobin Complexes

1996 • 89 citations

Pemphigus Sera Recognize Conformationally Sensitive Epitopes in the Amino-Terminal Region of Desmoglein-1

1995 • 87 citations

Both upstream and intron sequence elements are required for elevated expression of the rat somatic cytochrome c gene in COS-1 cells.

1988 • 82 citations

Autoantibodies against adhesion molecules and structures in blistering skin diseases.

1995 • 80 citations

Cadherin binding sites of plakoglobin: localization, specificity and role in targeting to adhering junctions

1996 • 78 citations

The molecular biology of desmosomes and hemidesmosomes: ′What's in a name?'

1992 • 73 citations

Identification of an epithelial protein related to the desmosome and intermediate filament network.

1992 • 60 citations

Genetic skin diseases caused by mutations in keratin intermediate filaments

1993 • 56 citations

Plakoglobin Binding by Human Dsg3 (Pemphigus Vulgaris Antigen) in Keratinocytes Requires the Cadherin-Like Intracytoplasmic Segment

1995 • 50 citations

Identification of the Domain of α-Catenin Involved in Its Association with β-Catenin and Plakoglobin (γ-Catenin)

1997 • 50 citations

Molecular Biology of Desmosomes and Hemidesmosomes

1994 • 46 citations

Expression of Full-Length Desmosomal Glycoproteins (Desmocollins) Is Not Sufficient to Confer Strong Adhesion on Transfected L929 Cells

1996 • 40 citations

Intracellular domain of desmoglein 3 (pemphigus vulgaris antigen) confers adhesive function on the extracellular domain of E-cadherin without binding catenins.

1995 • 29 citations

Desmoplakin expression and distribution in cultured rat bladder epithelial cells of varying tumorigenic potential

1991 • 28 citations

Pemphigus Vulgaris Antigen Lacks Biochemical Properties Characteristic of Classical Cadherins

1994 • 24 citations

Both Upstream and Intron Sequence Elements Are Required for Elevated Expression of the Rat Somatic Cytochrome c Gene in COS-1 Cells

1988 • 21 citations

Fractionation of desmosomes and comparison of the polypeptide composition of desmosomes prepared from two bovine epithelial tissues

1988 • 18 citations

Deleted Work

1955 • 0 citations