ATP-enhanced molecular chaperone functions of the small heat shock protein human αB crystallin

Protein folding in the cell

1992 • 4,138 citations

Molecular chaperones in cellular protein folding

1996 • 3,540 citations

Alpha-crystallin can function as a molecular chaperone.

1992 • 1,822 citations

Small heat shock proteins are molecular chaperones.

1993 • 1,376 citations

The crystal structure of the bacterial chaperonln GroEL at 2.8 Å

1994 • 1,322 citations

The crystal structure of the asymmetric GroEL–GroES–(ADP)7 chaperonin complex

1997 • 1,250 citations

Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation

1997 • 750 citations

Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones

1994 • 651 citations

Hsp90 chaperones protein folding in vitro

1992 • 514 citations

Molecular chaperones in cellular protein folding

1994 • 497 citations

GroE facilitates refolding of citrate synthase by suppressing aggregation

1991 • 486 citations

Evolution of the alpha-crystallin/small heat-shock protein family.

1993 • 464 citations

Supervising the fold: functional principles of molecular chaperones

1996 • 420 citations

The E. coli dnaK gene product, the hsp70 homolog, can reactivate heat-inactivated RNA polymerase in an ATP hydrolysis-dependent manner

1990 • 407 citations

The Chaperonin ATPase Cycle: Mechanism of Allosteric Switching and Movements of Substrate-Binding Domains in GroEL

1996 • 385 citations

Structure and Modifications of the Junior Chaperone α‐Crystallin

1994 • 374 citations

Transient Interaction of Hsp90 with Early Unfolding Intermediates of Citrate Synthase

1995 • 365 citations

Analysis of phosphate metabolites, the intracellular pH, and the state of adenosine triphosphate in intact muscle by phosphorus nuclear magnetic resonance.

1976 • 334 citations

Alpha B-crystallin in cardiac tissue. Association with actin and desmin filaments.

1992 • 302 citations

The reaction cycle of GroEL and GroES in chaperonin-assisted protein folding

1993 • 288 citations

The dnaK protein of Escherichia coli possesses an ATPase and autophosphorylating activity and is essential in an in vitro DNA replication system.

1983 • 260 citations

The Second Step of ATP Binding to DnaK Induces Peptide Release

1996 • 219 citations

α‐Crystallin Stabilizes Actin Filaments and Prevents Cytochalasin‐Induced Depolymerization in a Phosphorylation‐Dependent Manner

1996 • 166 citations

Conformational and Functional Differences between Recombinant Human Lens αA- and αB-Crystallin

1997 • 159 citations

Phosphorylation of HSP27 during development and decay of thermotolerance in Chinese hamster cells

1991 • 150 citations

The 90-kDa heat shock protein (hsp-90) possesses an ATP binding site and autophosphorylating activity.

1991 • 147 citations

Effects of Site-directed Mutations on the Chaperone-like Activity of αB-Crystallin

1996 • 146 citations

Alpha-crystallin/small heat shock protein has autokinase activity.

1994 • 138 citations

αB-Crystallin Expression in Mouse NIH 3T3 Fibroblasts: Glucocorticoid Responsiveness and Involvement in Thermal Protection

1993 • 126 citations

Heat shock in Escherichia coli alters the protein-binding properties of the chaperonin groEL by inducing its phosphorylation

1992 • 105 citations

Organophosphates of the crystalline lens: a nuclear magnetic resonance spectroscopic study.

1981 • 102 citations

Human αB-Crystallin

1997 • 90 citations

Conversion from Oligomers to Tetramers Enhances Autophosphorylation by Lens αA-Crystallin

1995 • 74 citations

The Influence of Some Post-Translational Modifications on the Chaperone-Like Activity of α-Crystallin

1996 • 74 citations

Modulation of the chaperone-like activity of bovine α-crystallin

1996 • 57 citations

Rapid Refolding Studies on the Chaperone-like α-Crystallin

1995 • 54 citations

Influence of the GroE molecular chaperone machine on the in vitro refolding of Escherichia coli β‐galactosidase

1996 • 46 citations

Interaction of ATP and lens alpha crystallin characterized by equilibrium binding studies and intrinsic tryptophan fluorescence spectroscopy

1995 • 44 citations

31P NMR studies of the ATP/α-crystallin complex: Functional implications

1992 • 34 citations

Eye Lens Nucleotides of Different Species of Vertebrates

1965 • 28 citations

Distribution of phosphatic metabolites in the crystalline lens.

1985 • 26 citations

Metabolism of glycerophosphate in the lens

1962 • 24 citations

Intrinsic Fluorescence Studies of the Chaperonin GroEL Containing Single Tyr → Trp Replacements Reveal Ligand-induced Conformational Changes

1996 • 13 citations