Influence of the GroE molecular chaperone machine on the in vitro refolding of Escherichia coli β‐galactosidase

Experiments in molecular genetics

1972 • 28,260 citations

The crystal structure of the bacterial chaperonln GroEL at 2.8 Å

1994 • 1,322 citations

Role of the Major Heat Shock Proteins as Molecular Chaperones

1993 • 1,096 citations

Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate

1991 • 853 citations

Reconstitution of active dimeric ribulose bisphosphate carboxylase from an unfolded state depends on two chaperonin proteins and Mg-ATP

1989 • 737 citations

GroE heat-shock proteins promote assembly of foreign prokaryotic ribulose bisphosphate carboxylase oligomers in Escherichia coli

1989 • 703 citations

Three-dimensional structure of β-galactosidase from E. coli.

1994 • 589 citations

Acid-induced folding of proteins.

1990 • 555 citations

GroE facilitates refolding of citrate synthase by suppressing aggregation

1991 • 486 citations

Sequence of the lacZ gene of Escherichia coli.

1983 • 465 citations

Dynamics of the Chaperonin ATPase Cycle: Implications for Facilitated Protein Folding

1994 • 461 citations

Molecular chaperones in protein folding: the art of avoiding sticky situations

1994 • 402 citations

Purification and properties of the groES morphogenetic protein of Escherichia coli.

1986 • 364 citations

GroEL-mediated protein folding proceeds by multiple rounds of binding and release of nonnative forms

1994 • 359 citations

Folding in vivo of bacterial cytoplasmic proteins: Role of GroEL

1993 • 345 citations

Location of a folding protein and shape changes in GroEL–GroES complexes imaged by cryo-electron microscopy

1994 • 334 citations

Molecular chaperones in cellular protein folding

1995 • 301 citations

Binding and hydrolysis of nucleotides in the chaperonin catalytic cycle: Implications for the mechanism of assisted protein folding

1993 • 266 citations

Characterization of a functionally important mobile domain of GroES

1993 • 222 citations

Hydrolysis of adenosine 5'-triphosphate by Escherichia coli GroEL: Effects of GroES and potassium ion

1993 • 192 citations

Complex interactions between the chaperonin 60 molecular chaperone and dihydrofolate reductase

1991 • 190 citations

Cooperativity in ATP hydrolysis by GroEL is increased by GroES

1991 • 189 citations

A polypeptide bound by the chaperonin groEL is localized within a central cavity.

1993 • 177 citations

Binding of a chaperonin to the folding intermediates of lactate dehydrogenase

1991 • 169 citations

On the role of groES in the chaperonin-assisted folding reaction. Three case studies.

1994 • 166 citations

[12]Refolding and association of oligomeric proteins

1986 • 165 citations

Selectivity of Intracellular Proteolysis: Protein Substrates Activate the ATP-Dependent Protease (La)

1986 • 112 citations

Conformational states of ribulose bisphosphate carboxylase and their interaction with chaperonin 60

1992 • 108 citations

Interaction of GroE with an all-beta-protein.

1992 • 103 citations

A study of the urea-produced subunits of β-galactosidase

1963 • 92 citations

Affinity of chaperonin-60 for a protein substrate and its modulation by nucleotides and chaperonin-10

1994 • 92 citations

Functional Significance of Symmetrical Versus Asymmetrical GroEL-GroES Chaperonin Complexes

1995 • 81 citations

Quasi-native Chaperonin-bound Intermediates in Facilitated Protein Folding

1995 • 66 citations

The folding of GroEL-bound barnase as a model for chaperonin-mediated protein folding.

1995 • 64 citations

A mutation in GroEL interferes with protein folding by reducing the rate of discharge of sequestered polypeptides.

1992 • 54 citations

On the effect of divalent cations and protein concentration upon renaturation of β-galactosidase from E. coli

1969 • 51 citations

Thermal switching between enhanced and arrested reactivation of bacterial glucose-6-phosphate dehydrogenase assisted by GroEL in the absence of ATP.

1993 • 45 citations

Structural and Functional Aspects of Chaperonin-Mediated Protein Folding

1994 • 44 citations

Thermal denaturation of .beta.-galactosidase and of two site specific mutants

1990 • 42 citations

Immunological study of complementary fragments of β-galactosidase

1974 • 38 citations

Chaperonin-mediated reconstitution of the phytochrome photoreceptor.

1993 • 33 citations

On the reversibility by treatment with urea of the thermal inactivation of E. coli β-galactosidase

1963 • 25 citations

Stable expression plasmid for high-level production of GroE molecular chaperones in large-scale cultures

1993 • 12 citations

The stability of β-galactosidase in the presence of urea

1969 • 8 citations

Chaperonins and Protein Folding

1994 • 3 citations