Modulation of the chaperone-like activity of bovine α-crystallin

Alpha-crystallin can function as a molecular chaperone.

1992 • 1,822 citations

Small heat shock proteins are molecular chaperones.

1993 • 1,376 citations

αB-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

1989 • 546 citations

αB subunit of lens-specific protein α-crystallin is present in other ocular and non-ocular tissues

1989 • 538 citations

Evolution of the alpha-crystallin/small heat-shock protein family.

1993 • 464 citations

Expression of the murine alpha B-crystallin gene is not restricted to the lens.

1989 • 377 citations

Structural and functional similarities of bovine alpha-crystallin and mouse small heat-shock protein. A family of chaperones.

1993 • 375 citations

Temperature‐induced exposure of hydrophobic surfaces and its effect on the chaperone activity of α‐crystallin

1995 • 278 citations

alpha A-crystallin is expressed in non-ocular tissues

1992 • 251 citations

Immunoreactive αA crystallin in rat non-lenticular tissues detected with a sensitive immunoassay method

1991 • 220 citations

Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescence.

1991 • 196 citations

Hypertonic stress induces αB-crystallin expression

1992 • 187 citations

The chaperone activity of bovine alpha crystallin. Interaction with other lens crystallins in native and denatured states.

1994 • 177 citations

Temperature dependent chaperone‐like activity of alpha‐crystallin

1995 • 159 citations

A Super-Family of Medium-Chain Dehydrogenases/Reductases (MDR). Sub-Lines including zeta-Crystallin, Alcohol and Polyol Dehydrogenases, Quinone Oxidoreductases, Enoyl Reductases, VAT-1 and other Proteins

1994 • 154 citations

A Super‐Family of Medium‐Chain Dehydrogenases/Reductases (MDR)

1994 • 131 citations

Evidence that α-crystallin prevents non-specific protein aggregation in the intact eye lens

1995 • 128 citations

Decreased Molecular Chaperone Property of α-Crystallins Due to Posttranslational Modifications

1995 • 121 citations

Alpha-crystallin can act as a chaperone under conditions of oxidative stress.

1995 • 114 citations

Stability and folding of ultrastable proteins: eye lens crystalline and enzymes from thermophiles ¹

1996 • 108 citations

On the interaction of α-crystallin with unfolded proteins

1995 • 102 citations

On the thermal stability of .alpha.-crystallin: z new insight from infrared spectroscopy

1995 • 97 citations

αB Crystallin Accumulation Is a Specific Response to Ha-ras and v-mos Oncogene Expression in Mouse NIH 3T3 Fibroblasts

1991 • 95 citations

Heat‐induced changes in the conformation of α‐ and β‐crystalline: Unique thermal stability of α‐crystallin

1988 • 95 citations

Cardiac alpha-crystallin

1990 • 79 citations

αB‐crystallin exists as an independent protein in the heart and in the lens

1991 • 71 citations

Inhibition of lens opacification during the early stages of cataract formation.

1995 • 59 citations

An investigation into the stability of α-crystallin by NMR spectroscopy; evidence for a two-domain structure

1993 • 56 citations

Translocation and induction of αB crystallin by heat shock in rat glioma (GA-1) cells

1992 • 55 citations

Diverse Gene Sequences Are Overexpressed in Werner Syndrome Fibroblasts Undergoing Premature Replicative Senescence

1991 • 46 citations

αB‐Crystallin is expressed in kidney epithelial cell lines and not in fibroblasts

1989 • 44 citations

Effect of cross-linking on the chaperone-like function of alpha crystallin

1995 • 44 citations

Diabetes Affects α-Crystallin Chaperone Function

1995 • 44 citations

Effect of Selected Anti-cataract Agents on Opacification in the Selenite Cataract Model

1996 • 43 citations

Chaperone-like activity of alpha-crystallin. The effect of NADPH on its interaction with zeta-crystallin.

1994 • 43 citations

Lens fiber cell differentiation and expression of crystallins in Co-cultures of human fetal lens epithelial cells and fibroblasts

1992 • 34 citations

An Avian αB-Crystallin

1993 • 32 citations

α-Crystallin-like Molecular Chaperone against the Thermal Denaturation of Lens Aldose Reductase: The Effect of Divalent Metal Ions

1995 • 26 citations

Expression of the Murine αB-Crystallin Gene Is Not Restricted to the Lens

1989 • 12 citations

Thermal denaturation of alpha-crystallin.

1989 • 2 citations

Thermal denaturation of alpha-crystallin.

1989 • 2 citations