Role of Protein-Phospholipid Interactions in the Activation of ARF1 by the Guanine Nucleotide Exchange Factor Arno

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα

1997 • 2,747 citations

Mechanisms of intracellular protein transport

1994 • 2,280 citations

Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential

1985 • 2,037 citations

PI3K: Downstream AKTion Blocks Apoptosis

1997 • 1,693 citations

ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity

1993 • 900 citations

Phospholipase D: a Downstream Effector of ARF in Granulocytes

1994 • 636 citations

Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase.

1996 • 560 citations

Characterization of Two Alternately Spliced Forms of Phospholipase D1

1997 • 547 citations

A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains

1996 • 465 citations

αLβ2 Integrin/LFA-1 Binding to ICAM-1 Induced by Cytohesin-1, a Cytoplasmic Regulatory Molecule

1996 • 439 citations

Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles.

1996 • 380 citations

N-Terminal Hydrophobic Residues of the G-Protein ADP-Ribosylation Factor-1 Insert into Membrane Phospholipids upon GDP to GTP Exchange

1997 • 351 citations

Structure and Function of ARF Proteins: Activators of Cholera Toxin and Critical Components of Intracellular Vesicular Transport Processes

1995 • 325 citations

The structure of the Escherichia coli EF-Tu· EF-Ts complex at 2.5 Å resolution

1996 • 289 citations

The pleckstrin homology domain of phospholipase C-.delta.1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes

1995 • 286 citations

Structure of the human ADP-ribosylation factor 1 complexed with GDP

1994 • 284 citations

Nucleotide exchange on ARF mediated by yeast Geal protein

1996 • 271 citations

The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport.

1992 • 259 citations

ARF: a key regulatory switch in membrane traffic and organelle structure

1994 • 258 citations

Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria.

1990 • 245 citations

Intracellular Distribution of Arf Proteins in Mammalian Cells

1996 • 235 citations

Phosphatidylinositol 4,5-Bisphosphate (PIP2)-enhanced G Protein-coupled Receptor Kinase (GRK) Activity: LOCATION, STRUCTURE, AND REGULATION OF THE PIP2 BINDING SITE DISTINGUISHES THE GRK SUBFAMILIES

1996 • 187 citations

Myristoylation of ADP-ribosylation Factor 1 Facilitates Nucleotide Exchange at Physiological Mg 2+ Levels

1995 • 185 citations

Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factor

1997 • 148 citations

Myristoylation-facilitated Binding of the G Protein ARF1GDP to Membrane Phospholipids Is Required for Its Activation by a Soluble Nucleotide Exchange Factor

1996 • 145 citations

Direct and GTP-dependent interaction of ADP ribosylation factor 1 with coatomer subunit β

1997 • 138 citations

The Pleckstrin Homology Domain Mediates Transformation by Oncogenic Dbl through Specific Intracellular Targeting

1996 • 136 citations

Coats and vesicle budding

1997 • 127 citations

The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms

1995 • 105 citations

The secretory pathway: mechanisms of protein sorting and transport

1996 • 73 citations

Phospholipid signalling: Rho is only ARF the story

1996 • 66 citations

Cloning and sequencing of a human cDNA from cytolytic NK/T cells with homology to yeast SEC7

1992 • 63 citations

Myristoylation is not required for GTP-dependent binding of ADP-ribosylation factor ARF1 to phospholipids.

1993 • 59 citations

Kinetic Analysis of Phospholipase C βIsoforms Using Phospholipid-Detergent Mixed Micelles

1995 • 54 citations