HSP70 and other possible heat shock or oxidative stress proteins are induced in skeletal muscle, heart, and liver during exercise

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

The Respiratory Chain and Oxidative Phosphorylation

1956 • 2,073 citations

Free radicals and tissue damage produced by exercise

1982 • 1,754 citations

Protein damage and degradation by oxygen radicals. I. general aspects.

1987 • 1,618 citations

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

Biochemical Adaptations in Muscle

1967 • 1,464 citations

Biogenesis of Mitochondria

1988 • 1,396 citations

The induction of gene activity in drosophila by heat shock

1979 • 1,308 citations

Heat shock, from bacteria to man

1982 • 1,260 citations

Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation

1990 • 869 citations

Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.

1985 • 860 citations

Protein Sorting to Mitochondria: Evolutionary Conservations of Folding and Assembly

1990 • 494 citations

Protein damage and degradation by oxygen radicals. IV. Degradation of denatured protein.

1987 • 482 citations

Cardiovascular Adaptations to Physical Training

1977 • 470 citations

Coordinated regulation of a set of genes by glucose and calcium ionophores in mammalian cells

1987 • 442 citations

Hydrogen peroxide-inducible proteins in Salmonella typhimurium overlap with heat shock and other stress proteins.

1986 • 442 citations

Biochemical adaptation of mitochondria, muscle, and whole-animal respiration to endurance training

1981 • 433 citations

Inducible repair of oxidative DNA damage in Escherichia coli

1983 • 415 citations

Oxygen radicals stimulate intracellular proteolysis and lipid peroxidation by independent mechanisms in erythrocytes.

1987 • 414 citations

Heat fractionation and thermotolerance: a review.

1978 • 364 citations

Turnover of bacterial glutamine synthetase: oxidative inactivation precedes proteolysis.

1981 • 347 citations

Coming in from the cold

1988 • 285 citations

Intracellular proteolytic systems may function as secondary antioxidant defenses: An hypothesis

1986 • 279 citations

Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions.

1983 • 273 citations

Temperature, skeletal muscle mitochondrial functions, and oxygen debt

1971 • 251 citations

Muscle Glycogen and Muscle Electrolytes during Prolonged Physical Exercise¹

1967 • 247 citations

Superoxide dismutase undergoes proteolysis and fragmentation following oxidative modification and inactivation.

1990 • 242 citations

Hydrogen peroxide or heat shock induces resistance to hydrogen peroxide in Chinese hamster fibroblasts

1987 • 217 citations

Endonuclease IV of Escherichia coli is induced by paraquat.

1987 • 188 citations

Macroxyproteinase (M.O.P.): A 670 kDa Proteinase complex that degrades oxidatively denatured proteins in red blood cells

1989 • 182 citations

Cardiovascular adjustments to exercise: Hemodynamics and mechanisms

1976 • 166 citations

Availability of substrates and capacity for prolonged heavy exercise in man.

1971 • 150 citations

Effect of exercise on synthesis and degradation of muscle protein

1980 • 145 citations

Degradation of oxidatively denatured proteins in Escherichia coli

1988 • 126 citations

Tissue temperatures and whole-animal oxygen consumption after exercise

1971 • 123 citations

Mitochondria contain a proteolytic system which can recognize and degrade oxidatively-denatured proteins

1988 • 122 citations

A role for reduced oxygen species in heat induced cell killing and the induction of thermotolerance

1988 • 85 citations

[47] Superoxide production

1984 • 82 citations

Expression of heat shock genes (hsp70) in the mammalian brain: Distinguishing constitutively expressed and hyperthermia‐inducible mRNA species

1990 • 81 citations

Vitamin E, Physical Exercise and Tissue Oxidative Damage

1983 • 78 citations

Exercise bioenergetics following sprint training

1982 • 62 citations

Ubisemiquinone radicals in liver: Implications for a mitochondrial Q cycle in vivo

1982 • 44 citations

Breakdown of aberrant protein in rabbit reticulocytes decreases with cell age

1980 • 37 citations

Expression of heat shock genes in fetal and maternal rabbit brain

1985 • 32 citations

Biology of Vitamin E: Ciba Foundation Symposium 101

1984 • 29 citations