Role of ICAM-3 in the initial interaction of T lymphocytes and APCs

Lipid rafts and signal transduction

2000 • 6,079 citations

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

1999 • 3,025 citations

Three-dimensional segregation of supramolecular activation clusters in T cells

1998 • 2,316 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Identification of DC-SIGN, a Novel Dendritic Cell–Specific ICAM-3 Receptor that Supports Primary Immune Responses

2000 • 1,665 citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

LAT

1998 • 1,251 citations

LAT Palmitoylation

1998 • 837 citations

Aggregation of Lipid Rafts Accompanies Signaling via the T Cell Antigen Receptor

1999 • 800 citations

Sequential Interactions of the TCR with Two Distinct Cytoplasmic Tyrosine Kinases

1994 • 711 citations

A Novel Adaptor Protein Orchestrates Receptor Patterning and Cytoskeletal Polarity in T-Cell Contacts

1998 • 708 citations

Selective modulation of protein kinase C-Θ during T-cell activation

1997 • 558 citations

Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes

1989 • 482 citations

Polarity of T Cell Shape, Motility, and Sensitivity to Antigen

1996 • 438 citations

Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes.

1992 • 437 citations

The structure and ligand interactions of CD2: implications for T-cell function

1996 • 397 citations

Differential Clustering of CD4 and CD3ζ During T Cell Recognition

2000 • 364 citations

Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes

1992 • 350 citations

Avidity regulation of integrins: the driving force in leukocyte adhesion

2000 • 342 citations

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes.

1996 • 324 citations

Cell Biology of Cytotoxic and Helper T Cell Functions: Immunofluorescence Microscopic Studies of Single Cells and Cell Couples

1989 • 296 citations

Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition

2000 • 295 citations

Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway.

1995 • 265 citations

A novel leukointegrin, αdβ2, binds preferentially to ICAM-3

1995 • 255 citations

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

1999 • 252 citations

Cytoskeletal Polarization of T Cells Is Regulated by an Immunoreceptor Tyrosine-based Activation Motif–dependent Mechanism

1998 • 247 citations

Moesin Interacts with the Cytoplasmic Region of Intercellular Adhesion Molecule-3 and Is Redistributed to the Uropod of T Lymphocytes during Cell Polarization

1997 • 238 citations

Signaling Takes Shape in the Immune System

2000 • 237 citations

Membrane rafts and signaling by the multichain immune recognition receptors

2000 • 226 citations

Characterization of the function of intercellular adhesion molecule (ICAM)-3 and comparison with ICAM-1 and ICAM-2 in immune responses.

1994 • 172 citations

ICAM-3 interacts with LFA-1 and regulates the LFA-1/ICAM-1 cell adhesion pathway.

1993 • 170 citations

Localization of LAT in Glycolipid-enriched Microdomains Is Required for T cell Activation

1999 • 166 citations

Cutting Edge: TCR Signaling Induces Selective Exclusion of CD43 from the T Cell-Antigen-Presenting Cell Contact Site

1998 • 123 citations

GrpL, a Grb2-related Adaptor Protein, Interacts with SLP-76 to Regulate Nuclear Factor of Activated T Cell Activation

1999 • 121 citations

Prolonged IL-2 receptor alpha/CD25 expression after T cell activation via the adhesion molecules CD2 and CD28. Demonstration of combined transcriptional and post-transcriptional regulation.

1992 • 115 citations

Polarization and interaction of adhesion molecules P-selectin glycoprotein ligand 1 and intercellular adhesion molecule 3 with moesin and ezrin in myeloid cells

2000 • 113 citations

Association of the Adaptor Molecule Lat with Cd4 and Cd8 Coreceptors Identifies a New Coreceptor Function in T Cell Receptor Signal Transduction

1999 • 110 citations

ICAM‐3, the third LFA‐1 counterreceptor, is a co‐stimulatory molecule for both resting and activated T lymphocytes

1993 • 100 citations

The hepatitis B virus X protein activates nuclear factor of activated T cells (NF-AT) by a cyclosporin A-sensitive pathway

1998 • 96 citations

ICAM-3 regulates lymphocyte morphology and integrin-mediated T cell interaction with endothelial cell and extracellular matrix ligands.

1994 • 86 citations

Lipid rafts mediate biosynthetic transport to the T lymphocyte uropod subdomain and are necessary for uropod integrity and function

2002 • 83 citations

Intercellular adhesion molecule‐3 is the predominant co‐stimulatory ligand for leukocyte function antigen‐1 on human blood dendritic cells

1995 • 81 citations

CD50 (intercellular adhesion molecule 3) stimulation induces calcium mobilization and tyrosine phosphorylation through p59fyn and p56lck in Jurkat T cell line.

1994 • 63 citations

Peptide antigen or superantigen-induced down-regulation of TCRs involves both stimulated and unstimulated receptors.

1997 • 62 citations

Characteristics of antigen‐independent and antigen‐dependent interaction of dendritic cells with CD4⁺ T cells

1995 • 57 citations

Co-stimulation of T cells results in distinct IL-10 and TNF-α cytokine profiles dependent on binding to ICAM-1, ICAM-2 or ICAM-3

1999 • 47 citations

Specific regulation of VLA-4 and alpha 4 beta 7 integrin expression on human activated T lymphocytes.

1996 • 34 citations

Segregation of co-stimulatory components into specific T cell surface lipid rafts

2001 • 34 citations

The ICAM-3/LFA-1 interaction is critical for epidermal Langerhans cell alloantigen presentation to CD4+ T cells

1995 • 32 citations