Dominant negative inhibition by fragments of a monomeric enzyme

Functional inactivation of genes by dominant negative mutations

1987 • 1,174 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain

1992 • 394 citations

Specific Sequence Homology and Three-Dimensional Structure of an Aminoacyl Transfer RNA Synthetase

1984 • 264 citations

Crystallographic study at 2·5 Å resolution of the interaction of methionyl-tRNA synthetase from Escherichia coli with ATP

1990 • 220 citations

Epitope-tagged ubiquitin. A new probe for analyzing ubiquitin function.

1991 • 212 citations

Expression of a truncated viral trans-activator selectively impedes lytic infection by its cognate virus

1988 • 169 citations

Evidence for Dispensable Sequences Inserted into a Nucleotide Fold

1987 • 157 citations

The N-terminal domains of acetylcholine receptor subunits contain recognition signals for the initial steps of receptor assembly

1992 • 149 citations

Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation, transdominant inhibition, and transformation suppression.

1993 • 131 citations

A Dominant Negative form of Transcription Activator mTFE3 Created by Differential Splicing

1991 • 129 citations

Inhibition of human immunodeficiency virus type 1 replication in human T cells by retroviral-mediated gene transfer of a dominant-negative Rev trans-activator.

1992 • 114 citations

Twin of I-POU: A two amino acid difference in the I-POU homeodomain distinguishes an activator from an inhibitor of transcription

1992 • 113 citations

Functional assembly of a randomly cleaved protein.

1992 • 96 citations

Unfolding and refolding of a type .kappa. immunoglobulin light chain and its variable and constant fragments

1987 • 77 citations

Role of diffusion in the folding of the .alpha. subunit of tryptophan synthase from Escherichia coli

1990 • 72 citations

Assembly of a class I tRNA synthetase from products of an artificially split gene

1991 • 67 citations

Dispensable pieces of an aminoacyl tRNA synthetase which activate the catalytic site

1984 • 62 citations

Antibody as an immunological probe for studying the refolding of bovine serum albumin. I. The catalysis of reoxidation of reduced bovine serum albumin by glutathione and a disulfide interchange enzyme.

1976 • 61 citations

Partly native epitopes are already present on early intermediates in the folding of tryptophan synthase.

1987 • 57 citations

Autonomous subdomains in protein folding

1994 • 43 citations

RNA binding determinant in some class I tRNA synthetases identified by alignment-guided mutagenesis.

1992 • 38 citations

Protein fragments as probes in the study of protein folding mechanisms: differential effects of dihydrofolate reductase fragments on the refolding of the intact protein.

1989 • 26 citations

Tripartite functional assembly of a large class I aminoacyl tRNA synthetase

1992 • 21 citations

C-Terminal Zinc-Containing Peptide Required for RNA Recognition by a Class I tRNA Synthetase

1996 • 19 citations

Intron locations and functional deletions in relation to the design and evolution of a subgroup of class I tRNA synthetases

1992 • 18 citations

Dominant lethality by expression of a catalytically inactive class I tRNA synthetase.

1993 • 15 citations

Functional Domains of Wild-Type and Mutant p53 Proteins Involved in Transcriptional Regulation, Transdominant Inhibition, and Transformation Suppression

1993 • 15 citations