Inhibition of human immunodeficiency virus type 1 replication in human T cells by retroviral-mediated gene transfer of a dominant-negative Rev trans-activator.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 6,811 citations

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 • 2,020 citations

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

1985 • 1,830 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA

1984 • 973 citations

Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposon Tn5

1982 • 936 citations

Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

1984 • 858 citations

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

1989 • 742 citations

Ribozymes as Potential Anti-HIV-1 Therapeutic Agents

1990 • 663 citations

Construction and use of a safe and efficient amphotropic packaging cell line

1988 • 637 citations

Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication

1990 • 437 citations

Intracellular immunization

1988 • 420 citations

Regulatory pathways governing HIV-1 replication

1989 • 401 citations

Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro

1989 • 377 citations

Effect of internal viral sequences on the utility of retroviral vectors

1987 • 351 citations

HIV-1 Gag mutants can dominantly interfere with the replication of the wild-type virus

1989 • 299 citations

Mutational definition of the human immunodeficiency virus type 1 Rev activation domain

1991 • 276 citations

Structure-based, C2 symmetric inhibitors of HIV protease

1990 • 213 citations

Human immunodeficiency virus as a prototypic complex retrovirus

1991 • 197 citations

Regulation of HIV and HTLV gene expression.

1988 • 128 citations

Identification oftrans-dominant HIV-1 rev protein mutants by direct transfer of bacterially produced proteins into human cells

1990 • 128 citations

Interleukin 4 promotes expression of mast cell ICAM-1 antigen.

1991 • 107 citations

A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat.

1990 • 95 citations

Identification and analysis of antisense RNA target regions of the human immunodeficiency virus type 1

1991 • 61 citations

Trans-dominant Tat mutants with alterations in the basic domain inhibit HIV-1 gene expression.

1991 • 54 citations

Expression of Chimeric Neo-Rev Response Element Sequences Interferes with Rev-Dependent HIV-1 Gag Expression

1992 • 12 citations

AIDS against the rest of the world

1991 • 8 citations