Induction of the interleukin-2/15 receptor β-chain by the EWS–WT1 translocation product

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

Involvement of chemokine receptors in breast cancer metastasis

2001 • 5,203 citations

Expression monitoring by hybridization to high-density oligonucleotide arrays

1996 • 2,796 citations

Stat3 as an Oncogene

1999 • 2,770 citations

WT-1 is required for early kidney development

1993 • 1,976 citations

Chromosomal translocations in human cancer

1994 • 1,551 citations

Cloning of a T Cell Growth Factor that Interacts with the β Chain of the Interleukin-2 Receptor

1994 • 1,423 citations

MMP-9 Supplied by Bone Marrow–Derived Cells Contributes to Skin Carcinogenesis

2000 • 1,306 citations

Interleukin 15: biology and relevance to human disease

2001 • 947 citations

Cytokine Signaling Through Nonreceptor Protein Tyrosine Kinases

1995 • 713 citations

THE MULTIFACETED REGULATION OF INTERLEUKIN-15 EXPRESSION AND THE ROLE OF THIS CYTOKINE IN NK CELL DIFFERENTIATION AND HOST RESPONSE TO INTRACELLULAR PATHOGENS

1999 • 712 citations

SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity

2001 • 695 citations

Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor.

1995 • 627 citations

The IL-2 Receptor Complex: Its Structure, Function, and Target Genes

1993 • 601 citations

Binding of the Wilms' Tumor Locus Zinc Finger Protein to the EGR-1 Consensus Sequence

1990 • 588 citations

Intra-abdominal desmoplastic small round-cell tumor. Report of 19 cases of a distinctive type of high-grade polyphenotypic malignancy affecting young individuals.

1991 • 553 citations

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1.

1993 • 501 citations

Intra-abdominal Desmoplastic Small Round-Cell Tumor

1991 • 486 citations

Functional Characterization of the Human Interleukin-15 Receptor αChain and Close Linkage of IL15RA and IL2RA Genes

1995 • 363 citations

Molecular Biology of the Ewing’s Sarcoma/Primitive Neuroectodermal Tumor Family

2000 • 355 citations

Repression of the gene encoding the TGF-β type II receptor is a major target of the EWS-FLI1 oncoprotein

1999 • 338 citations

Adrenomedullin Expression in Human Tumor Cell Lines ITS POTENTIAL ROLE AS AN AUTOCRINE GROWTH FACTOR

1996 • 311 citations

The Wilms Tumor Suppressor WT1 Encodes a Transcriptional Activator of amphiregulin

1999 • 308 citations

Characterization of the genomic breakpoint and chimeric transcripts in the EWS-WT1 gene fusion of desmoplastic small round cell tumor.

1995 • 296 citations

Wilms Tumor and the WT1 Gene

2001 • 291 citations

EWS, but Not EWS-FLI-1, Is Associated with Both TFIID and RNA Polymerase II: Interactions between Two Members of the TET Family, EWS and hTAF_II68, and Subunits of TFIID and RNA Polymerase II Complexes

1998 • 253 citations

Antigen retrieval techniques in immunohistochemistry: comparison of different methods

1997 • 245 citations

WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene

1999 • 243 citations

Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product

1995 • 181 citations

The multiple roles of tumour stroma

1997 • 174 citations

The EWS-WT1 translocation product induces PDGFA in desmoplastic small round-cell tumour

1997 • 171 citations

The WT1 Wilms' tumor suppressor gene: How much do we really know?

1996 • 168 citations

Interleukin-15 Is an Autocrine/Paracrine Viability Factor for Cutaneous T-Cell Lymphoma Cells

1998 • 162 citations

EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic

1997 • 159 citations

Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II

1998 • 148 citations

Expression of functional interleukin-15 receptor and autocrine production of interleukin-15 as mechanisms of tumor propagation in multiple myeloma

2000 • 129 citations

STAT Signaling in the Pathogenesis and Treatment of Cancer

1999 • 115 citations

The IGF-I Receptor Gene Promoter Is a Molecular Target for the Ewing's Sarcoma-Wilms' Tumor 1 Fusion Protein

1996 • 98 citations

Natural Splicing of Exon 2 of Human Interleukin-15 Receptor α-Chain mRNA Results in a Shortened Form with a Distinct Pattern of Expression

1999 • 92 citations

The Immediate-Early Gene Product Egr-1 Regulates the Human Interleukin-2 Receptor β-Chain Promoter through Noncanonical Egr and Sp1 Binding Sites

1997 • 86 citations

Characterization of the human interleukin-2 receptor beta-chain gene promoter: regulation of promoter activity by ets gene products.

1993 • 73 citations

The desmoplastic small round cell tumor t(11;22) translocation produces EWS/WT1 isoforms with differing oncogenic properties

1998 • 68 citations

Untitled

2001 • 61 citations

Interleukin-15 (IL-15) Can Replace the IL-2 Signal in IL-2–Dependent Adult T-Cell Leukemia (ATL) Cell Lines: Expression of IL-15 Receptor α on ATL Cells

1998 • 54 citations

IL-15 is produced by a subset of human melanomas, and is involved in the regulation of markers of melanoma progression through juxtacrine loops

1998 • 48 citations

Constitutive production of IL-2 by human carcinoma cells, expression of IL-2 receptor, and tumor cell growth.

1995 • 47 citations

The DNA binding domains of the WT1 tumor suppressor gene product and chimeric EWS/WT1 oncoprotein are functionally distinct

1998 • 42 citations

Interleukin‐15 blocks apoptosis and induces proliferation of the human myeloma cell line OH‐2 and freshly isolated myeloma cells

1999 • 37 citations

Molecular analysis of the IL-2 receptor β chain gene expressed in human tumor cells

1998 • 20 citations

Role of interleukin (IL)-2 and IL-15 in the tumour progression of a melanoma cell line MELP, derived from an IL-2 progressor patient

1997 • 11 citations

Wild-type p53-mediated down-modulation of interleukin 15 and interleukin 15 receptors in human rhabdomyosarcoma cells

1998 • 10 citations