G-protein-coupled receptor kinase 3- and protein kinase C-mediated desensitization of the PACAP receptor type 1 in human Y-79 retinoblastoma cells

G PROTEIN–COUPLED RECEPTOR KINASES

1998 • 1,335 citations

Differential signal transduction by five splice variants of the PACAP receptor

1993 • 1,185 citations

Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions.

2000 • 1,086 citations

THE ROLE OF RECEPTOR KINASES AND ARRESTINS IN G PROTEIN–COUPLED RECEPTOR REGULATION

1998 • 1,074 citations

Handbook of Physiology Section 7: Endocrinology

1976 • 448 citations

Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) and Its Receptors: Neuroendocrine and Endocrine Interaction

1995 • 388 citations

G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins

1996 • 332 citations

The 38-amino acid form of pituitary adenylate cyclase-activating polypeptide stimulates dual signaling cascades in PC12 cells and promotes neurite outgrowth.

1992 • 320 citations

G-protein-coupled receptors: turn-ons and turn-offs

1998 • 277 citations

G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins

1996 • 264 citations

Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors.

1993 • 234 citations

Inhibition of thrombin receptor signaling by a G-protein coupled receptor kinase. Functional specificity among G-protein coupled receptor kinases.

1994 • 218 citations

The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain

1992 • 197 citations

Cloning and Characterization of the Signal Transduction of Four Splice Variants of the Human Pituitary Adenylate Cyclase Activating Polypeptide Receptor

1996 • 187 citations

Phosphorylation and Desensitization of Human Endothelin A and B Receptors

1997 • 185 citations

Receptor and Gβγ isoform-specific interactions with G protein-coupled receptor kinases

1997 • 184 citations

A beta-adrenergic receptor kinase dominant negative mutant attenuates desensitization of the beta 2-adrenergic receptor.

1994 • 182 citations

Neural tube expression of pituitary adenylate cyclase-activating peptide (PACAP) and receptor: Potential role in patterning and neurogenesis

1998 • 170 citations

Functional Consequences of Altering Myocardial Adrenergic Receptor Signaling

2000 • 160 citations

Multiple receptors for PACAP and VIP

1994 • 158 citations

β2-Adrenergic Receptor Desensitization, Internalization, and Phosphorylation in Response to Full and Partial Agonists

1997 • 156 citations

β-ADRENERGIC RECEPTORS AND RECEPTOR SIGNALING IN HEART FAILURE

1999 • 153 citations

Partial agonists and G protein-coupled receptor desensitization

1999 • 139 citations

N‐Terminal Splice Variants of the Type I PACAP Receptor: Isolation, Characterization and Ligand Binding/Selectivity Determinants

1999 • 132 citations

Corticotropin-releasing factor (CRF) and glucocorticoids modulate the expression of type 1 CRF receptor messenger ribonucleic acid in rat anterior pituitary cell cultures.

1996 • 132 citations

Identification of Two Corticotropin‐Releasing Factor Receptors from Xenopus laevis with High Ligand Selectivity: Unusual Pharmacology of the Type 1 Receptor

1997 • 103 citations

Oligodeoxynucleotides antisense to mRNA encoding protein kinase A, protein kinase C, and beta-adrenergic receptor kinase reveal distinctive cell-type-specific roles in agonist-induced desensitization.

1994 • 95 citations

Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases.

1996 • 95 citations

Involvement of G Protein-Coupled Receptor Kinases and Arrestins in Desensitization to Follicle-Stimulating Hormone Action

1999 • 76 citations

Myocardial overexpression of GRK3 in transgenic mice: evidence for in vivo selectivity of GRKs

1998 • 72 citations

Mechanisms of Receptor Regulation

1985 • 70 citations

Involvement of G Protein-coupled Receptor Kinase 5 in Homologous Desensitization of the Thyrotropin Receptor

1996 • 65 citations

Regulation of Corticotropin‐Releasing Factor Receptor Function in Human Y‐79 Retinoblastoma Cells: Rapid and Reversible Homologous Desensitization but Prolonged Recovery

1997 • 62 citations

Regulation of cellular signal transduction pathways by desensitization and amplification

1994 • 62 citations

Selective Regulation of G Protein-Coupled Receptor-Mediated Signaling by G Protein-Coupled Receptor Kinase 2 in FRTL-5 Cells: Analysis of Thyrotropin, α_1B-Adrenergic, and A₁Adenosine Receptor-Mediated Responses

1999 • 58 citations

Functional and molecular expression of PACAP/VIP receptors in the rat retina

1998 • 57 citations

G Protein–Coupled Receptor Kinase Mediates Desensitization of Norepinephrine-Induced Ca2+ Channel Inhibition

1996 • 57 citations

The ligand‐selective Domains of Corticotropin‐Releasing Factor Type 1 and Type 2 Receptor Reside in Different Extracellular Domains

1999 • 51 citations

Corticotropin-releasing factor (CRF) and glucocorticoids modulate the expression of type 1 CRF receptor messenger ribonucleic acid in rat anterior pituitary cell cultures

1996 • 47 citations

Targeting G protein-coupled receptor kinases to their receptor substrates

1997 • 47 citations

Selective Reduction in A₂ Adenosine Receptor Desensitization Following Antisense‐Induced Suppression of G Protein‐Coupled Receptor Kinase 2 Expression

1999 • 38 citations

Protein Kinase C Deficiency Blocks Recovery from Agonist-induced Desensitization

1996 • 30 citations

Receptor Selectivity of the Cloned Opossum G Protein-Coupled Receptor Kinase 2 (GRK2) in Intact Opossum Kidney Cells: Role in Desensitization of Endogenous α 2C-Adrenergic but Not Serotonin 1B Receptors

1999 • 22 citations

Homologous desensitization of thromboxane A2 receptor in 1321N1 human astrocytoma cells.

1996 • 22 citations

Presence of Pituitary Adenylate Cyclase‐Activating Polypeptide Receptors in Y‐79 Human Retinoblastoma Cells

1996 • 22 citations

Involvement of G Protein-Coupled Receptor Kinases and Arrestins in Desensitization to Follicle-Stimulating Hormone Action

1999 • 17 citations

Involvement of β-Adrenergic Receptor Kinase-1 in Homologous Desensitization of Histamine H<sub>2</sub> Receptors in Human Gastric Carcinoma Cell Line MKN-45

1996 • 16 citations

Continuous Activation of Pituitary Adenylate Cyclase‐Activating Polypeptide Receptors Elicits Antipodal Effects on Cyclic AMP and Inositol Phospholipid Signaling Pathways in CATH.a Cells: Role of Protein Synthesis and Protein Kinases

1998 • 13 citations

Cellular Endocrinology

1992 • 11 citations

Receptor Selectivity of the Cloned Opossum G Protein-Coupled Receptor Kinase 2 (GRK2) in Intact Opossum Kidney Cells: Role in Desensitization of Endogenous 2C-Adrenergic but Not Serotonin 1B Receptors

1999 • 4 citations