Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

1983 • 2,009 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

1988 • 998 citations

Expression of a large family of POU-domain regulatory genes in mammalian brain development

1989 • 828 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells.

1982 • 754 citations

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.

1988 • 750 citations

The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

1988 • 670 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor.

1989 • 664 citations

Antigen presentation and tumor cytotoxicity by interferon‐γ‐treated microglial cells

1987 • 648 citations

Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence.

1984 • 564 citations

Contacts between Escherichia coli RNA polymerase and an early promoter of phage T7.

1980 • 524 citations

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

1987 • 516 citations

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

1988 • 494 citations

The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains.

1988 • 429 citations

Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter

1987 • 407 citations

Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells

1988 • 406 citations

A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein

1988 • 399 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1987 • 398 citations

The POU domain is a bipartite DNA-binding structure

1988 • 304 citations

Cloning of a Lymphoid-Specific cDNA Encoding a Protein Binding the Regulatory Octamer DNA Motif

1988 • 304 citations

SCIP: A glial POU domain gene regulated by cyclic AMP

1989 • 293 citations

Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic clipping bandshift assay (PCBA).

1988 • 284 citations

OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts

1987 • 255 citations

Morphology, growth, chromosomal pattern and fibrinolytic activity of two new human neuroblastoma cell lines.

1977 • 233 citations

Transcription of T cell receptor beta-chain genes is controlled by a downstream regulatory element.

1988 • 185 citations

Repression of the IgH Enhancer in Teratocarcinoma Cells Associated with a Novel Octamer Factor

1989 • 176 citations

Hyperinducibility of Ia antigen on astrocytes correlates with strain-specific susceptibility to experimental autoimmune encephalomyelitis.

1987 • 163 citations

Characteristics of the rat C-6 glioma maintained in organ culture systems. Production of glial fibrillary acidic protein in the absence of gliofibrillogenesis

1974 • 158 citations

Enhancer sequences and the regulation of gene transcription

1988 • 153 citations

The conserved decanucleotide from the immunoglobulin heavy chain promoter induces a very high transcriptional activity in B-cells when introduced into an heterologous promoter.

1987 • 144 citations

Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoter.

1989 • 139 citations

Independently evolving chicken histone H2B genes: identification of a ubiquitous H2B-specific 5′ element

1982 • 131 citations

How do different transcription factors binding the same DNA sequence sort out their jobs?

1989 • 126 citations

Human glioma-associated antigens detected by monoclonal antibodies.

1981 • 114 citations

Drosophila homoeotic genes encode transcriptional activators similar to mammalian OTF-2

1988 • 113 citations

Octamer motif mediates transcriptional repression of HSV immediate-early genes and octamer-containing cellular promoters in neuronal cells

1990 • 109 citations

Selective proteolysis defines two DNA binding domains in yeast transcription factor τ

1986 • 104 citations

Rapid test forin vivostability and DNA binding of mutated octamer binding proteins with ‘mini extracts’, prepared from a transfected cells

1989 • 91 citations

Octamer Transcription Factors 1 and 2 Each Bind to Two Different Functional Elements in the Immunoglobulin Heavy-Chain Promoter

1989 • 90 citations

Structure and methylation of the human calcitonin/α-CGRP gene

1989 • 79 citations

The DNA-binding homeo domain of the Oct-2 protein.

1989 • 59 citations

The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter.

1989 • 47 citations

A distinct octamer-binding protein present in malignant melanoma cells

1988 • 31 citations

Tissue specific gene expression

1990 • 29 citations

The HLA-DQβ gene upstream region contains an immunoglobulin-like octamer motif that binds cell-type specific nuclear factors

1987 • 19 citations