Structural gene products of the Ah locus. Genetic and immunochemical evidence for two forms of mouse liver cytochrome P-450 induced by 3-methylcholanthrene.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 3,435 citations

Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.

1976 • 1,343 citations

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

1976 • 1,180 citations

Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450

1976 • 536 citations

Contributions to behavior-genetic analysis : the mouse as a prototype

1970 • 462 citations

Purified liver microsomal cytochrome P-450. Separation and characterization of multiple forms.

1975 • 456 citations

Separation and purification of multiple forms of microsomal cytochrome P-450. Activities of different forms of cytochrome P-450 towards several compounds of environmental interest.

1977 • 367 citations

Drug interaction with hepatic microsomal cytochrome.

1966 • 335 citations

Genetic Expression of Aryl Hydrocarbon Hydroxylase Activity

1974 • 326 citations

A gel-electrophoretically homogeneous preparation of cytochrome P-450 from liver microsomes of phenobarbital-pretreated rabbits

1974 • 304 citations

Antigen-Binding Myeloma Proteins of Mice

1978 • 272 citations

Induction of multiple forms of mouse liver cytochrome P-450. Evidence for genetically controlled de novo protein synthesis in response to treatment with beta-naphthoflavone or phenobarbital.

1976 • 229 citations

The Ah Locus and the Metabolism of Chemical Carcinogens and Other Foreign Compounds

1977 • 188 citations

Genetic expression of aryl hydrocarbon hydroxylase induction. IV. Interaction of various compounds with different forms of cytochrome P-450 and the effect on benzo(a)pyrene metabolism in vitro.

1972 • 180 citations

Ontogenetic expression of polycyclic aromatic compound-inducible monooxygenase activities and forms of cytochrome P-450 in rabbit. Evidence for temporal control and organ specificity of two genetic regulatory systems.

1977 • 164 citations

Multiple forms of cytochrome P-450 in phenobarbital- and 3-methylcholanthrene-treated rats. Separation and spectral properties.

1975 • 150 citations

Purification of a substrate complex of cytochrome P-450 from liver microsomes of 3-methylcholanthrene-treated rabbits

1976 • 134 citations

Comparison of beta-naphthoflavone and 3-methylcholanthrene as inducers of hepatic cytochrome(s) P-448 and aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity.

1977 • 119 citations

Identification of the major cytochrome P-450 form transplacentally induced in neonatal rabbits by 3,3,7,8-tetrachlorodibenzo-p-dioxin.

1978 • 113 citations

Genetic Expression of Aryl Hydrocarbon Hydroxylase Induction

1974 • 103 citations

[24] Genetic differences in microsomal electron transport: The Ah Locus

1978 • 99 citations

Cytosolic receptor for aryl hydrocarbon hydroxylase induction by polycyclic aromatic compounds. Evidence for structural and regulatory variants among established cell cultured lines.

1977 • 96 citations

Evidence in Rat and Mouse Liver for Temporal Control of Two Forms of Cytochrome P-450 Inducible by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

1978 • 91 citations

Mendel's Principles of Heredity

1910 • 81 citations

Correlation of type I, type II, and reverse type I difference spectra with absolute changes in spin state of hepatic microsomal cytochrome P-450 iron from five mammalian species

1978 • 78 citations

Resolution of two forms of cytochrome P-450 from liver microsomes of rabbit treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.

1977 • 78 citations

ON THE SPATIAL ARRANGEMENT OF PROTEINS IN MICROSOMAL MEMBRANES FROM RAT LIVER

1974 • 59 citations

Separation of acetanilide and its hydroxylated metabolites and quantitative determination of “acetanilide 4-hydroxylase activity” by high-pressure liquid chromatography

1979 • 52 citations

Further Studies on Genetically Mediated Differences in Monooxygenase Activities and Spin State of Cytochrome P450 Iron from Rabbit, Rat, and Mouse Liver

1973 • 47 citations

[20] Reconstitution of the cytochrome P-450-containing mixed-function oxidase system of liver microsomes

1978 • 33 citations

Spectral Evidence for Weak Ligand in Sixth Position of Hepatic Microsomal Cytochrome P-450 Low Spin Ferric Iron <i>in viv</i><i>o</i>

1978 • 24 citations

Coordinated polypeptide synthesis and insertion of protoheme in cytochrome P-450 during development of endoplasmic reticulum membranes

1978 • 24 citations

The Ah Locus: Aromatic Hydrocarbon Responsiveness... of Mice and Men

1978 • 19 citations