Genetic Expression of Aryl Hydrocarbon Hydroxylase Activity

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

Arene oxides and the NIH shift: The metabolism, toxicity and carcinogenicity of aromatic compounds

1972 • 593 citations

Evidence for a new P-450 hemoprotein in hepatic microsomes from methylcholanthrene treated rats

1966 • 418 citations

Studies on the induction of CO-binding pigments in liver microsomes by phenobarbital and 3-methylcholanthrene

1967 • 334 citations

Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a potent inducer of aryl hydrocarbon hydroxylase, with 3-methylcholanthrene.

1974 • 293 citations

Genetic Regulation of Aryl Hydrocarbon Hydroxylase Induction

1972 • 247 citations

Existence and Separation of Three Forms of Cytochrome P-450 from Rat Liver Microsomes

1973 • 221 citations

Chlorinated dibenzo-p-dioxins: potent inducers of delta-aminolevulinic acid synthetase and aryl hydrocarbon hydroxylase. II. A study of the structure-activity relationship.

1973 • 218 citations

Aryl Hydrocarbon Hydroxylase Induction by Polycyclic Hydrocarbons: Simple Autosomal Dominant Trait in the Mouse

1972 • 213 citations

Multiplicity of cytochrome P450 hemoproteins in rat liver microsomes

1974 • 200 citations

Genetic expression of aryl hydrocarbon hydroxylase induction. IV. Interaction of various compounds with different forms of cytochrome P-450 and the effect on benzo(a)pyrene metabolism in vitro.

1972 • 180 citations

Evidence for two forms of P-450 hemoprotein in microsomal membranes

1966 • 136 citations

Gel electrophoresis of partially purified cytochromes P450 from liver microsomes of variously-treated rats

1973 • 136 citations

Influence of hepatic microsomal mixed function oxidation reactions on cellular metabolic control

1971 • 128 citations

Genetic Differences in the Extent of Aryl Hydrocarbon Hydroxylase Induction in Mouse Fetal Cell Cultures

1970 • 96 citations

Genetic Regulation of Aryl Hydrocarbon Hydroxylase Induction

1973 • 93 citations

Genetic Expression of Aryl Hydrocarbon Hydroxylase Induction

1973 • 69 citations

Aryl hydrocarbon hydroxylase, epoxide hydrase, and 7,12-dimethylbenz(a)anthracene-produced skin tumorigenesis in the mouse.

1972 • 67 citations

Aryl hydrocarbon (benzo [α] pyrene) hydroxylase: Inducible in extrahepatic tissues of mouse strains not inducible in liver

1973 • 67 citations

Aryl Hydrocarbon Hydroxylase Induction in Mammalian Liver Cell Culture

1971 • 66 citations

Genetic expression of aryl hydrocarbon hydroxylase induction

1973 • 59 citations

Aryl Hydrocarbon Hydroxylase Induction in Mammalian Liver Cell Culture

1972 • 58 citations

Genetic expression of aryl hydrocarbon hydroxylase induction. 3. Changes in the binding of n-octylamine to cytochrome P-450.

1972 • 48 citations

Further Studies on Genetically Mediated Differences in Monooxygenase Activities and Spin State of Cytochrome P450 Iron from Rabbit, Rat, and Mouse Liver

1973 • 47 citations

Klinische und experimentelle Untersuchungen zur �tiologie der Chloracne

1957 • 47 citations

Toxicology of Chlorinated Dibenzo-p-dioxins

1973 • 36 citations

Guidelines for nomenclature of genetically determined biochemical variants in the house mouse, Mus musculus

1973 • 27 citations

Use of fetal cell culture as an experimental system for predicting drug metabolism in the intact animal

1973 • 24 citations

Changes in aryl hydrocarbon hydroxylase activity and microsomal P450 during polycyclic hydrocarbon treatment of mammalian cells in culture

1969 • 16 citations

Particular Activity of Naphthacene Derivatives as Inducers of Zoxazolamine Hydroxylase Synthesis in Rats

1967 • 6 citations