Release of oxygen metabolites from chemoattractant-stimulated neutrophils is inhibited by resting platelets: role of extracellular adenosine and actin polymerization

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1968 • 5,084 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides

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Adenosine, an endogenous anti-inflammatory agent

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Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.

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Superoxide generation by digitonin-stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system.

1978 • 428 citations

The adenosine/neutrophil paradox resolved: human neutrophils possess both A1 and A2 receptors that promote chemotaxis and inhibit O2 generation, respectively.

1990 • 377 citations

Cytoprotective function of nitric oxide: Inactivation of superoxide radicals produced by human leukocytes

1991 • 368 citations

Adenosine; a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils.

1985 • 345 citations

Increased levels of cyclic adenosine-3',5'-monophosphate in human polymorphonuclear leukocytes after surface stimulation.

1980 • 193 citations

P-selectin mediates Ca(2+)-dependent adhesion of activated platelets to many different types of leukocytes: detection by flow cytometry

1992 • 160 citations

Respiratory burst oxidase and three of four oxidase-related polypeptides are associated with the cytoskeleton of human neutrophils.

1991 • 148 citations

Adhesion protein GMP140 inhibits superoxide anion release by human neutrophils.

1991 • 107 citations

Analysis of the bimodal chemiluminescence pattern stimulated in human neutrophils by chemotactic factors

1983 • 99 citations

The effects of adenosine agonists on human neutrophil function.

1986 • 95 citations

ATP induces transient elevations of [Ca2+]i in human neutrophils and primes these cells for enhanced O2- generation.

1988 • 95 citations

Platelet enhancement of O2-. responses in stimulated human neutrophils. Identification of platelet factor as adenine nucleotide.

1988 • 94 citations

Biophysical properties and microfilament assembly in neutrophils: modulation by cyclic AMP.

1991 • 91 citations

Contact-induced neutrophil activation by platelets in human cell suspensions and whole blood

1992 • 82 citations

Botulinum C2 toxin ADP-ribosylates actin and enhances O2- production and secretion but inhibits migration of activated human neutrophils.

1988 • 77 citations

Chemotactic Peptide Induces cAMP Elevation in Human Neutrophils by Amplification of the Adenylate Cyclase Response to Endogenously Produced Adenosine

1989 • 74 citations

Monokines Mediate Decreased Hepatic Glucocorticoid Binding in Endotoxemia

1991 • 68 citations

The role of the cytosolic free Ca2+ transient for fMet-Leu-Phe induced actin polymerization in human neutrophils.

1986 • 60 citations

Increased breakdown of phosphatidylinositol 4,5-bisphosphate is not an initiating factor for actin assembly in human neutrophils.

1988 • 58 citations

Polymorphonuclear leukocyte chemiluminescence induced by formylmethionyl-leucyl-phenylalanine and phorbol myristate acetate: Effects of catalase and superoxide dismutase

1987 • 58 citations

Interactions between neutrophils and endothelial cells

1993 • 55 citations

Inhibition of inositol phospholipids metabolism and calcium mobilization by cyclic AMP-increasing agents and phorbol ester in neutrophils

1986 • 47 citations

The role of cyclic AMP, calcium and filamentous actin in adenosine modulation of Fc receptor-mediated phagocytosis in human neutrophils

1994 • 47 citations

Bidirectional modulation of platelet and polymorphonuclear leukocyte activities

1993 • 44 citations

Regulation of human neutrophil functions by adenine nucleotides.

1989 • 42 citations

Platelet Modulation of Neutrophil Superoxide Anion Production

1990 • 41 citations

Release of adenosine and its metabolites from activated human leucocytes

1986 • 39 citations

Effects of fibronectin on actin organization and respiratory burst activity in neutrophils, monocytes, and macrophages

1994 • 37 citations

Platelet-derived growth factor stimulates phagocytosis and blocks agonist-induced activation of the neutrophil oxidative burst: a possible cellular mechanism to protect against oxygen radical damage.

1987 • 37 citations

Botulinum C₂ toxin potentiates activation of the neutrophil oxidase Further evidence of a role for actin polymerization

1987 • 36 citations

Modulation of neutrophil functions by activated platelet release factors

1992 • 34 citations

Actin polymerization modifies stimulus-oxidase coupling in rat neutrophils

1987 • 31 citations

Platelets amplify chemotactic peptide-induced changes in F-actin and calcium in human neutrophils.

1994 • 23 citations

Erythrocyte enhancement of C3b-mediated phagocytosis by human neutrophils in vitro: a combined effect of the erythrocyte complement receptors CR1 and erythrocyte scavengers to reactive oxygen metabolites (ROM).

1985 • 10 citations

Polymorphonuclear leukocyte adhesion to endothelial cells is inhibited by resting platelets.

1992 • 8 citations

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