Increased levels of cyclic adenosine-3',5'-monophosphate in human polymorphonuclear leukocytes after surface stimulation.

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Isolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet Aggregation

1974 • 1,004 citations

Mechanisms of Lysosomal Enzyme Release from Human Leukocytes II. EFFECTS OF cAMP AND cGMP, AUTONOMIC AGONISTS, AND AGENTS WHICH AFFECT MICROTUBULE FUNCTION

1974 • 567 citations

Superoxide generation by digitonin-stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system.

1978 • 428 citations

MECHANISMS OF LYSOSOMAL ENZYME RELEASE FROM HUMAN LEUKOCYTES

1973 • 346 citations

beta-Adrenergic receptor agonists increase phospholipid methylation, membrane fluidity, and beta-adrenergic receptor-adenylate cyclase coupling.

1979 • 308 citations

Changes in membrane potential of human granulocytes antecede the metabolic responses to surface stimulation

1978 • 218 citations

Changes in ionic movements across rabbit polymorphonuclear leukocyte membranes during lysosomal enzyme release. Possible ionic basis for lysosomal enzyme release.

1977 • 181 citations

The ability of chemotactic factors to induce lysosomal enzyme release. II. The mechanism of release.

1974 • 154 citations

Influence of local anesthetics upon human polymorphonuclear leukocyte function in vitro. Reduction of lysosomal enzyme release and superoxide anion production.

1977 • 136 citations

The Ability of Chemotactic Factors to Induce Lysosomal Enzyme Release

1974 • 128 citations

HORMONAL CONTROL OF LYSOSOMAL ENZYME RELEASE FROM HUMAN NEUTROPHILS

1974 • 124 citations

Bioregulation of lysosomal enzyme secretion from human neutrophils: roles of guanosine 3':5'-monophosphate and calcium in stimulus-secretion coupling.

1975 • 123 citations

Changes in membrane microviscosity associated with phagocytosis: effects of colchicine.

1977 • 117 citations

Hormonal Control of Lysosomal Enzyme Release from Human Neutrophils: Elevation of Cyclic Nucleotide Levels by Autonomic Neurohormones

1974 • 102 citations

The Effects of Extracellular K+, Na+ and Ca++ on Lysosomal Enzyme Secretion from Polymorphonuclear Leukocytes

1977 • 100 citations

MEDIATION OF IMMUNOLOGIC DISCHARGE OF LYSOSOMAL ENZYMES FROM HUMAN NEUTROPHILS BY GUANOSINE 3',5'-MONOPHOSPHATE

1974 • 69 citations

The role of calcium and cyclic adenosine 3′,5′-monophosphate in the regulation of glycogen metabolism in phagocytozing human polymorphonuclear leukocytes

1978 • 56 citations

The effect of polystyrene beads on cyclic 3′,5′-adenosine monophosphate concentration in leukocytes

1971 • 54 citations

Quantitative phagocytosis by neutrophils. I. A new method with immune complexes.

1973 • 49 citations

Microtubules and cyclic amp in human leukocytes: on the order of things

1978 • 46 citations

Hormonal Control of Neutrophil Lysosomal Enzyme Release: Effect of Epinephrine on Adenosine 3′,5′-Monophosphate

1974 • 31 citations

Regulation of iodine metabolism in human leukocytes by adenosine 3′,5′-monophosphate

1972 • 23 citations

Effects of catecholamines and glucagon on glycogen metabolism in human polymorphonuclear leukocytes

1978 • 18 citations

Restrained Adenyl Cyclase in Human Neutrophils: Stimulation of Cyclic Adenosine 3':5'-Monophosphate Formation and Adenyl Cyclase Activity by Phagocytosis and Prostaglandins

1974 • 15 citations

Evidence that cyclic AMP is not the chemical mediator of the metabolic changes accompanying phagocytosis.

1974 • 9 citations

An artifact produced by boiling adenyl cyclase reaction mixtures prior to the cyclic AMP-radioimmunoassay

1978 • 6 citations