Conformational changes induced by DNA binding of NF-κB

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

Estimation of globular protein secondary structure from circular dichroism

1981 • 2,139 citations

The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

1990 • 900 citations

Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

1990 • 870 citations

Thiordoxin regulates the DNA binding activity of NF-χB by reduction of a disulphid bond involving cysteine 62

1992 • 825 citations

Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro.

1991 • 649 citations

DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

1991 • 604 citations

Structure of NF-κB p50 homodimer bound to a κB site

1995 • 564 citations

Structure of the NF-κB p50 homodimer bound to DNA

1995 • 525 citations

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

1989 • 517 citations

Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin

1993 • 490 citations

Dorsal , an Embryonic Polarity Gene in Drosophila , Is Homologous to the Vertebrate Proto-Oncogene, c- rel

1987 • 485 citations

Dif, a dorsal-related gene that mediates an immune response in Drosophila

1993 • 464 citations

Isolation of a rel -related Human cDNAThat Potentially Encodes the 65-kD Subunit of NF-κB

1991 • 448 citations

The inducible transcription factor NF-κB: structure-function relationship of its protein subunits

1993 • 429 citations

Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65

1991 • 410 citations

Folding transition in the DMA-binding domain of GCN4 on specific binding to DNA

1990 • 378 citations

RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B.

1992 • 375 citations

Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B.

1992 • 373 citations

DNA binding of purified transcription factor NF-kappa B. Affinity, specificity, Zn2+ dependence, and differential half-site recognition.

1991 • 349 citations

Nucleic acid sequences of the oncogene v-rel in reticuloendotheliosis virus strain T and its cellular homolog, the proto-oncogene c-rel

1984 • 295 citations

NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit.

1991 • 287 citations

A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site.

1992 • 281 citations

Altered protein conformation on DNA binding by Fos and Jun

1990 • 193 citations

The inhibitory ankyrin and activator Rel proteins

1992 • 185 citations

The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein.

1992 • 174 citations

A human rel proto-oncogene cDNA containing an Alu fragment as a potential coding exon.

1989 • 171 citations

I-Rel: a novel rel-related protein that inhibits NF-kappa B transcriptional activity.

1992 • 167 citations

Role of cysteine₆₂in DNA recognition by the P50 subunit of NF-_xB

1993 • 142 citations

N-terminal DNA-binding domains contribute to differential DNA-binding specificities of NF-kappa B p50 and p65.

1993 • 126 citations

RelB, a New Rel Family Transcription Activator That Can Interact with p50-NF-κB

1992 • 110 citations

Distinctive DNA conformation with enlarged major groove is found in Zn-finger-DNA and other protein-DNA complexes.

1994 • 104 citations

A Novel Mitogen-Inducible Gene Product Related to p50/pl05- NF-κB Participates in Transactivation through a κB Site

1992 • 77 citations

The RxxRxRxxC Motif Conserved in All Rel/κΒ Proteins Is Essential for the DNA-Binding Activity and Redox Regulation of the v-Rel Oncoprotein

1992 • 51 citations

Sequence requirement for specific interaction of an enhancer binding protein (EBP1) with DNA

1989 • 47 citations

Interaction of enhancer-binding protein EBP1 (NF-kappa B) with the human immunodeficiency virus type 1 enhancer

1990 • 40 citations

Interaction of the C-terminal region of p105 with the nuclear localisation signal of p50 is required for inhinition of NF-ϰB binding activity

1993 • 34 citations

Evidence for a non-alpha-helical DNA-binding motif in the Rel homology region.

1994 • 32 citations

Enhancer binding protein (EBP1) makes base and backbone contacts over one complete turn of the DNA double helix

1989 • 22 citations

Acquisition of NFKB1-Selective DNA Binding by Substitution of Four Amino Acid Residues from NFKB1 into RelA

1993 • 22 citations

The DNA recognition subunit of a DNA methyltransferase is predominantly a molten globule in the absence of DNA

1994 • 15 citations

DNA binding alters the protease susceptibility of the p50 subunit of NF-ϰB

1993 • 14 citations

Homodimer of p50 (NFκB1) does not introduce a substantial directed bend into DNA according to three different experimental assays

1995 • 14 citations