Acquisition of NFKB1-Selective DNA Binding by Substitution of Four Amino Acid Residues from NFKB1 into RelA

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

A general method ofin vitropreparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

1988 • 2,410 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

TRANSCRIPTION FACTORS: Structural Families and Principles of DNA Recognition

1992 • 1,411 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

The inducible transcription activator NF-κB: regulation by distinct protein subunits

1991 • 1,079 citations

The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

1990 • 900 citations

Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

1990 • 870 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B.

1991 • 805 citations

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

1991 • 746 citations

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention.

1992 • 731 citations

DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

1991 • 604 citations

Selection of Optimal κB/Rel DNA-Binding Motifs: Interaction of Both Subunits of NF-κB with DNA Is Required for Transcriptional Activation

1992 • 501 citations

Dorsal , an Embryonic Polarity Gene in Drosophila , Is Homologous to the Vertebrate Proto-Oncogene, c- rel

1987 • 485 citations

Rapid and efficient purification of native histidine-tagged protein expressed by recombinant vaccinia virus.

1991 • 464 citations

Isolation of a rel -related Human cDNAThat Potentially Encodes the 65-kD Subunit of NF-κB

1991 • 448 citations

Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA

1990 • 445 citations

Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65

1991 • 410 citations

The precursor of NF-κB p50 has IκB-like functions

1992 • 409 citations

B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κB p50

1991 • 403 citations

Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-κB subunit

1992 • 399 citations

In Vitro Activation and Nuclear Translocation of NF-κB Catalyzed by Cyclic AMP-Dependent Protein Kinase and Protein Kinase C

1989 • 389 citations

RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B.

1992 • 375 citations

Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B.

1992 • 373 citations

Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs

1990 • 330 citations

The v-rel oncogene encodes a κB enhancer binding protein that inhibits NF-κB function

1990 • 325 citations

Generation of p50 subunit of NF-kB by processing of p105 through an ATP-dependent pathway

1991 • 316 citations

Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro.

1988 • 309 citations

The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression.

1992 • 288 citations

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation.

1992 • 286 citations

IκBγ, a 70 kd protein identical to the C-terminal half of p110 NF-κB: A new member of the IκB family

1992 • 274 citations

NF-κB, KBF1, dorsal, and related matters

1990 • 267 citations

Rel-Associated pp40: an Inhibitor of the Rel Family of Transcription Factors

1991 • 255 citations

Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation.

1992 • 245 citations

The dorsal morphogen is a sequence-specific DNA-binding protein that interacts with a long-range repression element in drosophila

1991 • 229 citations

The rel-associated pp40 protein prevents DNA binding of Rel and NF-kappa B: relationship with I kappa B beta and regulation by phosphorylation.

1991 • 210 citations

Single amino acid substitutions alter helix-loop-helix protein specificity for bases flanking the core CANNTG motif.

1992 • 199 citations

Cytoplasmic retention, DNA binding and processing of the NF-kappa B p50 precursor are controlled by a small region in its C-terminus.

1991 • 182 citations

The NF-kappa B p50 precursor, p105, contains an internal I kappa B-like inhibitor that preferentially inhibits p50.

1992 • 178 citations

Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative.

1992 • 177 citations

The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein.

1992 • 174 citations

I-Rel: a novel rel-related protein that inhibits NF-kappa B transcriptional activity.

1992 • 167 citations

The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain.

1990 • 164 citations

Rapid induction in regenerating liver of RL/IF-1 (an I kappa B that inhibits NF-kappa B, RelB-p50, and c-Rel-p50) and PHF, a novel kappa B site-binding complex.

1992 • 155 citations

Acquisition of myogenic specificity by replacement of three amino acid residues from MyoD into E12

1992 • 147 citations

Transcriptional regulation of the HIV-1 promoter by NF-kappa B in vitro.

1992 • 146 citations

Inhibition of transcription factors belonging to the rel/NF-kappa B family by a transdominant negative mutant.

1991 • 138 citations

Bioassay for trans-activation using purified human immunodeficiency virus tat-encoded protein: trans-activation requires mRNA synthesis.

1989 • 132 citations

N-terminal DNA-binding domains contribute to differential DNA-binding specificities of NF-kappa B p50 and p65.

1993 • 126 citations

Conservation of Transcriptional Activation Functions of the NF-κB p50 and p65 Subunits in Mammalian Cells and Saccharomyces cerevisiae

1993 • 77 citations

Mutational analysis of the p50 subunit of NF-kappa B and inhibition of NF-kappa B activity by trans-dominant p50 mutants

1993 • 57 citations

The Mouse c-rel Protein Has an N-Terminal Regulatory Domain and a C-Terminal Transcriptional Transactivation Domain

1990 • 50 citations

Deleted Work

1955 • 0 citations