Adenovirus terminal protein mediates both nuclear matrix association and efficient transcription of adenovirus DNA.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

1984 • 1,088 citations

Identification of a nuclear protein matrix

1974 • 1,016 citations

Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct.

1979 • 975 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

1986 • 922 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Transcriptional regulation of hemoglobin switching in chicken embryos.

1981 • 800 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

1989 • 781 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Topoisomerase II is a structural component of mitotic chromosome scaffolds.

1985 • 751 citations

A nuclear DNA attachment element mediates elevated and position-independent gene activity

1989 • 597 citations

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster

1986 • 587 citations

Metaphase chromosome structure

1986 • 538 citations

Identification of a protein linked to the ends of adenovirus DNA

1977 • 502 citations

Localization of topoisomerase II in mitotic chromosomes.

1985 • 501 citations

In situ localization of DNA topoisomerase II, a major polypeptide component of the Drosophila nuclear matrix fraction.

1985 • 472 citations

THE ROLE OF THE NUCLEAR MATRIX IN THE ORGANIZATION AND FUNCTION OF DNA

1986 • 360 citations

The primary transcription unit of the mouse β-Major globin gene

1981 • 358 citations

A circular DNA—Protein complex from adenoviruses

1973 • 311 citations

The organisation of chromatin loops: characterization of a scaffold attachment site

1986 • 308 citations

The Adenovirus E1B-55K Transforming Polypeptide Modulates Transport or Cytoplasmic Stabilization of Viral and Host Cell mRNAs

1986 • 301 citations

The matrix attachment regions of the chicken lysozyme gene co-map with the boundaries of the chromatin domain.

1988 • 280 citations

Chromosomal ARS and CEN elements bind specifically to the yeast nuclear scaffold

1988 • 251 citations

Identification of the gene and mRNA for the adenovirus terminal protein precursor

1981 • 227 citations

A structural analysis of the role of the nuclear matrix and DNA loops in the organization of the nucleus and chromosome

1984 • 220 citations

The nuclear matrix: Structure and composition

1988 • 220 citations

Enhancement of RNA polymerase III transcription by the E1A gene product of adenovirus

1985 • 188 citations

Matrix attachment regions are positioned near replication initiation sites, genes, and an interamplicon junction in the amplified dihydrofolate reductase domain of Chinese hamster ovary cells.

1988 • 177 citations

A general method for preparing chromatin containing intact DNA.

1985 • 161 citations

Adenovirus stimulation of transcription by RNA polymerase III: evidence for an E1A-dependent increase in transcription factor IIIC concentration.

1986 • 156 citations

Dissection of overlapping functions within the adenovirus type 5 E1A gene.

1984 • 146 citations

The nucleoskeleton: Artefact, passive framework or active site?

1988 • 143 citations

Structure and Development of Viruses as Observed in the Electron Microscope

1969 • 129 citations

The replication of adenovirus DNA with purified proteins

1983 • 125 citations

The association of transcribed genes with the nuclear matrix ofDrosophilacells during heat shock

1985 • 114 citations

Adenovirus terminal protein precursor. Partial amino acid sequence and the site of covalent linkage to virus DNA.

1982 • 102 citations

Processing of the adenovirus terminal protein

1981 • 99 citations

Anchorage of the Chinese hamster dihydrofolate reductase gene to the nuclear scaffold occurs in an intragenic region

1987 • 99 citations

Sequence-Independent Autoregulation of the Adenovirus Type 5 E1A Transcription Unit

1985 • 86 citations

Early events in the interaction of adenoviruses with HeLa cells

1972 • 82 citations

Adenovirus DNA Replication

1984 • 62 citations

Regulation of Adenovirus Mrna Formation

1986 • 59 citations

In vitro cleavage specificity of the adenovirus type 2 proteinase

1983 • 58 citations

Alterations in nuclear matrix structure after adenovirus infection

1987 • 56 citations

African swine fever virus-induced polypeptides in vero cells

1986 • 49 citations

The terminal regions of adenovirus and minute virus of mice DNAs are preferentially associated with the nuclear matrix in infected cells

1989 • 42 citations

Codon insertion mutants of the adenovirus terminal protein.

1986 • 41 citations

Adenovirus DNA is associated with the nuclear matrix of infected cells

1982 • 40 citations

Concentration Dependence of Transcriptional Transactivation in Inducible E1A-Containing Human Cells

1988 • 31 citations

Adenovirus preterminal protein synthesized in COS cells from cloned DNA is active in DNA replication in vitro

1988 • 22 citations

Nuclear matrix-intermediate filament system and its alteration in adenovirus infected Hela cell

1988 • 10 citations

The Influence of a Gonadotrophin on the Seasonal Changes in the Testis and Deferent Duct of the Chaffinch (Fringilla coelebs)

1949 • 9 citations