Concentration Dependence of Transcriptional Transactivation in Inducible E1A-Containing Human Cells

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

1985 • 805 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

Identification of a cellular transcription factor involved in E1A trans-activation

1986 • 551 citations

[17] Plasmid cloning vehicles derived from plasmids ColE1, F, R6K, and RK2

1979 • 508 citations

Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids

1981 • 489 citations

A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing

1988 • 485 citations

ADENOVIRUS PROMOTERS AND E1A TRANSACTIVATION

1986 • 460 citations

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

1982 • 353 citations

Oestrogen and glucocorticoid responsive elements are closely related but distinct

1987 • 353 citations

Analysis of adenovirus transforming proteins from early regions 1A and 1B with antisera to inducible fusion antigens produced in Escherichia coli

1984 • 349 citations

The Adenovirus E1B-55K Transforming Polypeptide Modulates Transport or Cytoplasmic Stabilization of Viral and Host Cell mRNAs

1986 • 301 citations

Glucocorticoids enhance stability of human growth hormone mRNA.

1987 • 250 citations

Complete transformation by adenovirus 2 requires both E1A proteins

1984 • 243 citations

Activation of the human beta-interferon gene requires an interferon-inducible factor.

1986 • 237 citations

E1A 13S and 12S mRNA Products Made in Escherichia coli Both Function as Nucleus-Localized Transcription Activators but Do Not Directly Bind DNA

1985 • 190 citations

Enhancement of RNA polymerase III transcription by the E1A gene product of adenovirus

1985 • 188 citations

Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis

1984 • 186 citations

Cis-acting induction of adenovirus transcription

1983 • 180 citations

Transcription Control by Oncogenes

1985 • 176 citations

Adenovirus stimulation of transcription by RNA polymerase III: evidence for an E1A-dependent increase in transcription factor IIIC concentration.

1986 • 156 citations

Dissection of overlapping functions within the adenovirus type 5 E1A gene.

1984 • 146 citations

A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2.

1983 • 141 citations

Individual products of the adenovirus 12S and 13S EIa mRNAs stimulate viral EIIa and EIII expression at the transcriptional level.

1984 • 138 citations

Identification of an E1A-inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter.

1987 • 133 citations

Selective Induction of Human Heat Shock Gene Transcription by the Adenovirus E1A Gene Products, Including the 12S E1A Product

1987 • 123 citations

A Consensus Sequence for the Adenovirus-2 Genome

1986 • 92 citations

Mapping of a gene coding for a major late structural polypeptide on the vaccinia virus genome

1984 • 89 citations

Activation of the Human β-Interferon Gene Requires an Interferon-Inducible Factor

1986 • 78 citations

Expression of adenovirus E1a and E1b gene products and the Escherichia coli XGPRT gene in KB cells

1983 • 68 citations

Stimulation of the adenovirus E2 promoter by simian virus 40 T antigen or E1A occurs by different mechanisms.

1986 • 67 citations

Glucocorticoids Enhance Stability of Human Growth Hormone mRNA

1987 • 62 citations

Factors responsible for the higher transcriptional activity of extracts of adenovirus-infected cells fractionate with the TATA box transcription factor.

1988 • 60 citations

Introduction, stable integration, and controlled expression of a chimeric adenovirus gene whose product is toxic to the recipient human cell.

1984 • 59 citations

Upstream regulatory regions required to stabilize binding to the TATA sequence in an adesovirus early promoter

1987 • 57 citations

Alterations in nuclear matrix structure after adenovirus infection

1987 • 56 citations

Transcription control region within the protein-coding portion of adenovirus E1A genes.

1984 • 48 citations

Adenovirus transforming 19-kD T antigen has an enhancer-dependent trans-activation function and relieves enhancer repression mediated by viral and cellular genes.

1987 • 48 citations

Stimulation of the Adenovirus E2 Promoter by Simian Virus 40 T Antigen or E1A Occurs by Different Mechanisms

1986 • 37 citations

Progressive reorganization of the host cell cytoskeleton during adenovirus infection

1986 • 32 citations

Mapping a eukaryotic promoter: a DNA sequence required for in vivo expression of adenovirus pre-early functions.

1981 • 31 citations

Activation of adenovirus 5 E1A transcription by region E1B in transformed primary rat cells.

1987 • 30 citations

Expression of adenovirus type 12 early region 1 in KB cells transformed by recombinants containing the gene

1983 • 26 citations

Expression of transfected vimentin genes in differentiating murine erythroleukemia cells reveals divergent cis-acting regulation of avian and mammalian vimentin sequences.

1987 • 24 citations

Transcription Control Region Within the Protein-Coding Portion of Adenovirus E1A Genes

1984 • 17 citations