RAP, a novel type of ER chaperone

Protein folding in the cell

1992 • 4,138 citations

MOLECULAR CHAPERONE FUNCTIONS OF HEAT-SHOCK PROTEINS

1993 • 1,591 citations

Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

1985 • 1,585 citations

STRUCTURES AND FUNCTIONS OF MULTILIGAND LIPOPROTEIN RECEPTORS: Macrophage Scavenger Receptors and LDL Receptor-Related Protein (LRP)

1994 • 1,175 citations

The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor.

1993 • 652 citations

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.

1991 • 586 citations

Molecular Identification of a Novel Candidate Sorting Receptor Purified from Human Brain by Receptor-associated Protein Affinity Chromatography

1997 • 401 citations

A novel mechanism for controlling the activity of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein.

1992 • 341 citations

Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP).

1994 • 323 citations

Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator.

1992 • 318 citations

Inhibition of Hepatic Chylomicron Remnant Uptake by Gene Transfer of a Receptor Antagonist

1994 • 311 citations

39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein.

1995 • 305 citations

RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors.

1996 • 274 citations

Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo.

1995 • 270 citations

The human alpha 2-macroglobulin receptor: identification of a 420-kD cell surface glycoprotein specific for the activated conformation of alpha 2-macroglobulin.

1990 • 268 citations

Molecular Characterization of a Novel Human Hybrid-type Receptor That Binds the α2-Macroglobulin Receptor-associated Protein

1996 • 236 citations

Primary structure of alpha 2-macroglobulin receptor-associated protein. Human homologue of a Heymann nephritis antigen

1991 • 230 citations

Apolipoprotein E-containing High Density Lipoprotein Promotes Neurite Outgrowth and Is a Ligand for the Low Density Lipoprotein Receptor-related Protein

1996 • 226 citations

Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neurons

1994 • 217 citations

7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway

1994 • 200 citations

The 39-kDa receptor-associated protein interacts with two members of the low density lipoprotein receptor family, alpha 2-macroglobulin receptor and glycoprotein 330.

1992 • 190 citations

Analysis of ligand recognition by the purified alpha 2-macroglobulin receptor (low density lipoprotein receptor-related protein). Evidence that high affinity of alpha 2-macroglobulin-proteinase complex is achieved by binding to adjacent receptors

1991 • 186 citations

The 39-kDa receptor-associated protein regulates ligand binding by the very low density lipoprotein receptor.

1994 • 177 citations

Receptor-associated Protein Is a Folding Chaperone for Low Density Lipoprotein Receptor-related Protein

1996 • 162 citations

gp330 associates with a 44-kDa protein in the rat kidney to form the Heymann nephritis antigenic complex.

1992 • 141 citations

Subcellular localization and endocytic function of low density lipoprotein receptor-related protein in human glioblastoma cells.

1994 • 138 citations

The 39-kDa Receptor-associated Protein Modulates Lipoprotein Catabolism by Binding to LDL Receptors

1995 • 121 citations

A gene for a low density lipoprotein receptor-related protein in the nematode Caenorhabditis elegans.

1993 • 114 citations

Identification of a cell line that expresses a cell surface and a soluble form of the gp330/receptor-associated protein (RAP) Heymann nephritis antigenic complex.

1993 • 88 citations

Molecular Analysis of Ligand Binding to the Second Cluster of Complement-type Repeats of the Low Density Lipoprotein Receptor-related Protein

1997 • 86 citations

Molecular cloning of a cDNA encoding a major pathogenic domain of the Heymann nephritis antigen gp330.

1990 • 84 citations

Two receptor systems are involved in the plasma clearance of tissue-type plasminogen activator (t-PA) in vivo.

1995 • 84 citations

MHC class II antigen processing: biology of invariant chain

1994 • 83 citations

Identification of domains on the 39-kDa protein that inhibit the binding of ligands to the low density lipoprotein receptor-related protein.

1993 • 78 citations

39-kD protein inhibits tissue-type plasminogen activator clearance in vivo.

1993 • 75 citations

Interaction of a 39 kDa protein with the low-density-lipoprotein-receptor-related protein (LRP) on rat hepatoma cells

1993 • 73 citations

A Heparin Binding Protein Whose Expression Increases during Differentiation of Embryonal Carcinoma Cells to Parietal Endoderm Cells: cDNA Cloning and Sequence Analysis1

1990 • 67 citations

Differential Functions of Triplicated Repeats Suggest Two Independent Roles for the Receptor-associated Protein as a Molecular Chaperone

1997 • 65 citations

Disulfide bridges of a cysteine-rich repeat of the LDL receptor ligand-binding domain

1995 • 56 citations

The MHC class II-associated invariant chain: a molecule with multiple roles in MHC class II biosynthesis and antigen presentation to CD4+ T cells.

1996 • 54 citations

Dissection of the Domain Architecture of the α₂macroglobulin‐Receptor‐Associated Protein

1997 • 46 citations

ERD2 proteins mediate ER retention of the HNEL signal of LRP’s receptor-associated protein (RAP)

1997 • 41 citations

The solution structure of the N-terminal domain of α₂-macroglobulin receptor-associated protein

1997 • 40 citations

Sites within the 39-kDa protein important for regulating ligand binding to the low-density lipoprotein receptor-related protein

1995 • 35 citations

Binding analysis of amino-terminal and carboxyl-terminal regions of the 39-kDa protein to the low density lipoprotein receptor-related protein.

1994 • 33 citations

The receptor-associated protein (RAP) binds calmodulin and is phosphorylated by calmodulin-dependent kinase II.

1996 • 29 citations

Inhibitory Effect on the Lipolysis-stimulated Receptor of the 39-kDa Receptor-associated Protein

1995 • 26 citations