A gene for a low density lipoprotein receptor-related protein in the nematode Caenorhabditis elegans.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

1991 • 3,108 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.

1988 • 947 citations

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.

1990 • 944 citations

The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins

1985 • 845 citations

THE LDL RECEPTOR LOCUS IN FAMILIAL HYPERCHOLESTEROLEMIA: Mutational Analysis of a Membrane Protein

1990 • 684 citations

The LDL–receptor–related protein, LRP, is an apolipoprotein E-binding protein

1989 • 680 citations

Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.

1990 • 666 citations

Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins.

1989 • 600 citations

The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border.

1982 • 539 citations

Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes.

1992 • 464 citations

Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein.

1990 • 451 citations

Genome linking with yeast artificial chromosomes

1988 • 438 citations

Integrative transformation of Caenorhabditis elegans

1986 • 417 citations

glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins

1989 • 345 citations

Evidence that the newly cloned low‐density‐lipoprotein receptor related protein (LRP) is the α₂‐macroglobulin receptor

1990 • 320 citations

Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator.

1992 • 318 citations

Tissue-specific synthesis of yolk proteins in Caenorhabditis elegans

1983 • 308 citations

Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins

1989 • 307 citations

Plasminogen activators in tissue remodeling and invasion: mRNA localization in mouse ovaries and implanting embryos.

1989 • 287 citations

The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch

1988 • 281 citations

Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment.

1990 • 279 citations

Autoimmune Target in Heymann Nephritis Is a Glycoprotein with Homology to the LDL Receptor

1989 • 268 citations

Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor.

1982 • 260 citations

Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.

1992 • 244 citations

Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein.

1990 • 239 citations

Transcript analysis of glp-1 and lin-12, homologous genes required for cell interactions during development of C. elegans

1989 • 201 citations

Caenorhabditis elegans expressed sequence tags identify gene families and potential disease gene homologues

1992 • 191 citations

Cassette of Eight Exons Shared by Genes for LDL Receptor and EGF Precursor

1985 • 185 citations

Sterol Requirement for Reproduction of a Free-Living Nematode

1968 • 179 citations

Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects.

1990 • 151 citations

Ultrastructural localization by monoclonal antibodies of brush border antigens expressed by glomeruli. II. Extrarenal distribution.

1986 • 131 citations

Identification of the rat Heymann nephritis autoantigen (GP330) as a receptor site for plasminogen

1991 • 119 citations

Low density lipoprotein receptor-related protein mediates endocytosis of monoclonal antibodies in cultured cells and rabbit liver.

1990 • 119 citations

The minor myosin heavy chain, mhcA, of Caenorhabditis elegans is necessary for the initiation of thick filament assembly.

1989 • 114 citations

Lipoprotein binding and endosomal itinerary of the low density lipoprotein receptor-related protein in rat liver.

1989 • 112 citations

Insertion of part of an intron into the 5' untranslated region of a Caenorhabditis elegans gene converts it into a trans-spliced gene.

1991 • 100 citations

GENETIC ORGANIZATION OF THE REGION AROUND UNC-15 (I), A GENE AFFECTING PARAMYOSIN IN CAENORHABDITIS ELEGANS

1980 • 63 citations

The laying hen expresses two different low density lipoprotein receptor-related proteins.

1991 • 62 citations

Structure and Function of a Lipoprotein: Lipovitellin

1991 • 62 citations

Structure of alpha 2-macroglobulin from the arthropod Limulus polyphemus

1991 • 36 citations

Insertion of Part of an Intron into the 5′ Untranslated Region of a Caenorhabditis elegans Gene Converts It into a Zraws-Spliced Gene

1991 • 32 citations